| Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein AJ Firestone, JS Weinger, M Maldonado, K Barlan, LD Langston, ... Nature 484 (7392), 125-129, 2012 | 398 | 2012 |
| Principles and concepts of DNA replication in bacteria, archaea, and eukarya M O’Donnell, L Langston, B Stillman Cold Spring Harbor perspectives in biology 5 (7), a010108, 2013 | 397 | 2013 |
| Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork RE Georgescu, L Langston, NY Yao, O Yurieva, D Zhang, J Finkelstein, ... Nature structural & molecular biology 21 (8), 664-670, 2014 | 220 | 2014 |
| CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication LD Langston, D Zhang, O Yurieva, RE Georgescu, J Finkelstein, NY Yao, ... Proceedings of the National Academy of Sciences 111 (43), 15390-15395, 2014 | 187 | 2014 |
| Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation RE Georgescu, GD Schauer, NY Yao, LD Langston, O Yurieva, D Zhang, ... Elife 4, e04988, 2015 | 154 | 2015 |
| Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase C Indiani, LD Langston, O Yurieva, MF Goodman, M O'Donnell Proceedings of the National Academy of Sciences 106 (15), 6031-6038, 2009 | 132 | 2009 |
| DNA replication: keep moving and don't mind the gap LD Langston, M O'Donnell Molecular cell 23 (2), 155-160, 2006 | 104 | 2006 |
| DNA Polymerase δ Is Highly Processive with Proliferating Cell Nuclear Antigen and Undergoes Collision Release upon Completing DNA∗ LD Langston, M O'Donnell Journal of biological chemistry 283 (43), 29522-29531, 2008 | 94 | 2008 |
| The top3+ gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activity M Maftahi, CS Han, LD Langston, JC Hope, N Zigouras, GA Freyer Nucleic acids research 27 (24), 4715-4724, 1999 | 89 | 1999 |
| Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery LD Langston, C Indiani, M O'Donnell Cell Cycle 8 (17), 2686-2691, 2009 | 87 | 2009 |
| Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks LD Langston, R Mayle, GD Schauer, O Yurieva, D Zhang, NY Yao, ... Elife 6, e29118, 2017 | 78 | 2017 |
| Gene targeting in yeast is initiated by two independent strand invasions LD Langston, LS Symington Proceedings of the National Academy of Sciences 101 (43), 15392-15397, 2004 | 66 | 2004 |
| A proposal: Evolution of PCNA's role as a marker of newly replicated DNA R Georgescu, L Langston, M O’Donnell DNA repair 29, 4-15, 2015 | 54 | 2015 |
| Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase L Langston, M O’Donnell Elife 6, e23449, 2017 | 52 | 2017 |
| Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression R Mayle, L Langston, KR Molloy, D Zhang, BT Chait, ME O’Donnell Proceedings of the National Academy of Sciences 116 (3), 798-803, 2019 | 37 | 2019 |
| Opposing roles for DNA structure‐specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting LD Langston, LS Symington The EMBO journal 24 (12), 2214-2223, 2005 | 35 | 2005 |
| Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest D Bastia, P Srivastava, S Zaman, M Choudhury, BK Mohanty, J Bacal, ... Proceedings of the National Academy of Sciences 113 (26), E3639-E3648, 2016 | 34 | 2016 |
| Intrachromosomal tandem duplication and repeat expansion during attempts to inactivate the subtelomeric essential gene GSH1 in Leishmania A Mukherjee, LD Langston, M Ouellette Nucleic acids research 39 (17), 7499-7511, 2011 | 33 | 2011 |
| An explanation for origin unwinding in eukaryotes LD Langston, ME O'Donnell Elife 8, e46515, 2019 | 30 | 2019 |
| Subunit sharing among high-and low-fidelity DNA polymerases LD Langston, M O’Donnell Proceedings of the National Academy of Sciences 109 (31), 12268-12269, 2012 | 7 | 2012 |
Bruce StillmanCold Spring Harbor LaboratoryVerified email at cshl.edu
