Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice SP Heximer, RH Knutsen, X Sun, KM Kaltenbronn, MH Rhee, N Peng, ... The Journal of clinical investigation 111 (4), 445-452, 2003 | 409 | 2003 |
Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency G Faury, M Pezet, RH Knutsen, WA Boyle, SP Heximer, SE McLean, ... The Journal of clinical investigation 112 (9), 1419-1428, 2003 | 298 | 2003 |
Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor–null mice C Bernal-Mizrachi, S Weng, C Feng, BN Finck, RH Knutsen, TC Leone, ... Nature medicine 9 (8), 1069-1075, 2003 | 266 | 2003 |
Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries JE Wagenseil, NL Nerurkar, RH Knutsen, RJ Okamoto, DY Li, ... American Journal of Physiology-Heart and Circulatory Physiology 289 (3 …, 2005 | 232 | 2005 |
Elastic fiber formation: a dynamic view of extracellular matrix assembly using timer reporters BA Kozel, BJ Rongish, A Czirok, J Zach, CD Little, EC Davis, RH Knutsen, ... Journal of cellular physiology 207 (1), 87-96, 2006 | 207 | 2006 |
Vascular respiratory uncoupling increases blood pressure and atherosclerosis C Bernal-Mizrachi, AC Gates, S Weng, T Imamura, RH Knutsen, ... Nature 435 (7041), 502-506, 2005 | 198 | 2005 |
Reduced vessel elasticity alters cardiovascular structure and function in newborn mice JE Wagenseil, CH Ciliberto, RH Knutsen, MA Levy, A Kovacs, ... Circulation research 104 (10), 1217-1224, 2009 | 132 | 2009 |
An afferent vagal nerve pathway links hepatic PPARα activation to glucocorticoid-induced insulin resistance and hypertension C Bernal-Mizrachi, L Xiaozhong, L Yin, RH Knutsen, MJ Howard, ... Cell metabolism 5 (2), 91-102, 2007 | 131 | 2007 |
Functional rescue of elastin insufficiency in mice by the human elastin gene: implications for mouse models of human disease E Hirano, RH Knutsen, H Sugitani, CH Ciliberto, RP Mecham Circulation research 101 (5), 523-531, 2007 | 115 | 2007 |
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension SL Merklinger, RA Wagner, E Spiekerkoetter, A Hinek, RH Knutsen, ... Circulation research 97 (6), 596-604, 2005 | 111 | 2005 |
Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems JS Weinbaum, TJ Broekelmann, RA Pierce, CC Werneck, F Segade, ... Journal of biological chemistry 283 (37), 25533-25543, 2008 | 110 | 2008 |
Elastin protein levels are a vital modifier affecting normal lung development and susceptibility to emphysema A Shifren, AG Durmowicz, RH Knutsen, E Hirano, RP Mecham American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (3 …, 2007 | 109 | 2007 |
Discrete contributions of elastic fiber components to arterial development and mechanical compliance L Carta, JE Wagenseil, RH Knutsen, B Mariko, G Faury, EC Davis, ... Arteriosclerosis, thrombosis, and vascular biology 29 (12), 2083-2089, 2009 | 99 | 2009 |
Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice VP Le, RH Knutsen, RP Mecham, JE Wagenseil American Journal of Physiology-Heart and Circulatory Physiology 301 (1 …, 2011 | 96 | 2011 |
The importance of elastin to aortic development in mice JE Wagenseil, CH Ciliberto, RH Knutsen, MA Levy, A Kovacs, ... American Journal of Physiology-Heart and Circulatory Physiology 299 (2 …, 2010 | 87 | 2010 |
Williams Syndrome Predisposes to Vascular Stiffness Modified by Antihypertensive Use and Copy Number Changes in NCF1 BA Kozel, JR Danback, JL Waxler, RH Knutsen, L de Las Fuentes, ... Hypertension 63 (1), 74-79, 2014 | 83 | 2014 |
Hypotension due to Kir6. 1 gain‐of‐function in vascular smooth muscle A Li, RH Knutsen, H Zhang, P Osei‐Owusu, A Moreno‐Dominguez, ... Journal of the American Heart Association 2 (4), e000365, 2013 | 76 | 2013 |
Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo MD Combs, RH Knutsen, TJ Broekelmann, HM Toennies, TJ Brett, ... Journal of Biological Chemistry 288 (40), 28869-28880, 2013 | 72 | 2013 |
Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice X Ma, M Tittiger, RH Knutsen, A Kovacs, L Schaller, RP Mecham, ... Molecular genetics and metabolism 94 (3), 298-304, 2008 | 63 | 2008 |
Albumin contributes to kidney disease progression in Alport syndrome G Jarad, RH Knutsen, RP Mecham, JH Miner American Journal of Physiology-Renal Physiology 311 (1), F120-F130, 2016 | 55 | 2016 |