| DNA-binding specificities of human transcription factors A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ... Cell 152 (1), 327-339, 2013 | 1406 | 2013 |
| A survey of human brain transcriptome diversity at the single cell level S Darmanis, SA Sloan, Y Zhang, M Enge, C Caneda, LM Shuer, ... Proceedings of the National Academy of Sciences 112 (23), 7285-7290, 2015 | 1355 | 2015 |
| Counting absolute numbers of molecules using unique molecular identifiers T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ... Nature methods 9 (1), 72-74, 2012 | 1297 | 2012 |
| Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors N Issaeva, P Bozko, M Enge, M Protopopova, LGGC Verhoef, M Masucci, ... Nature medicine 10 (12), 1321-1328, 2004 | 969 | 2004 |
| MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011 | 758 | 2011 |
| Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ... The EMBO journal 29 (13), 2147-2160, 2010 | 675 | 2010 |
| DNA-dependent formation of transcription factor pairs alters their binding specificity A Jolma, Y Yin, KR Nitta, K Dave, A Popov, M Taipale, M Enge, T Kivioja, ... Nature 527 (7578), 384-388, 2015 | 578 | 2015 |
| Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities A Jolma, T Kivioja, J Toivonen, L Cheng, G Wei, M Enge, M Taipale, ... Genome research 20 (6), 861-873, 2010 | 534 | 2010 |
| Single-cell analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns M Enge, HE Arda, M Mignardi, J Beausang, R Bottino, SK Kim, SR Quake Cell 171 (2), 321-330. e14, 2017 | 526 | 2017 |
| CTCF/cohesin-binding sites are frequently mutated in cancer R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ... Nature genetics 47 (7), 818-821, 2015 | 469 | 2015 |
| Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ... Cell 154 (4), 801-813, 2013 | 395 | 2013 |
| Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci R Jäger, G Migliorini, M Henrion, R Kandaswamy, HE Speedy, A Heindl, ... Nature communications 6 (1), 6178, 2015 | 250 | 2015 |
| Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ... Science 338 (6112), 1360-1363, 2012 | 238 | 2012 |
| Converting adult pancreatic islet α cells into β cells by targeting both Dnmt1 and Arx H Chakravarthy, X Gu, M Enge, X Dai, Y Wang, N Damond, C Downie, ... Cell metabolism 25 (3), 622-634, 2017 | 219 | 2017 |
| MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53 M Enge, W Bao, E Hedström, SP Jackson, A Moumen, G Selivanova Cancer cell 15 (3), 171-183, 2009 | 194 | 2009 |
| Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer J Zawacka-Pankau, VV Grinkevich, S Hünten, F Nikulenkov, A Gluch, H Li, ... Journal of Biological Chemistry 286 (48), 41600-41615, 2011 | 147 | 2011 |
| Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis VV Grinkevich, F Nikulenkov, Y Shi, M Enge, W Bao, A Maljukova, ... Cancer cell 15 (5), 441-453, 2009 | 140 | 2009 |
| Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2 H Li, T Lakshmikanth, C Garofalo, M Enge, C Spinnler, A Anichini, ... Cell cycle 10 (19), 3346-3358, 2011 | 117 | 2011 |
| A highly scalable method for joint whole-genome sequencing and gene-expression profiling of single cells V Zachariadis, H Cheng, N Andrews, M Enge Molecular Cell 80 (3), 541-553. e5, 2020 | 67 | 2020 |
| Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors L Cui, I Moraga, T Lerbs, C Van Neste, S Wilmes, N Tsutsumi, ... Proceedings of the National Academy of Sciences 118 (2), e2017849118, 2021 | 35 | 2021 |
Jussi TaipaleUniversity of Cambridge, Department of BiochemistryVerified email at cam.ac.uk
