How insulin receptor substrate proteins regulate the metabolic capacity of the liver-implications for health and disease L Fritsche, C Weigert, HU Haring, R Lehmann Current medicinal chemistry 15 (13), 1316-1329, 2008 | 195 | 2008 |
Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease C Baumeier, L Schlüter, S Saussenthaler, T Laeger, M Rödiger, SA Alaze, ... Molecular metabolism 6 (10), 1254-1263, 2017 | 131 | 2017 |
Effects of resveratrol supplementation on liver fat content in overweight and insulin‐resistant subjects: A randomized, double‐blind, placebo‐controlled clinical trial K Kantartzis, L Fritsche, M Bombrich, J Machann, F Schick, H Staiger, ... Diabetes, Obesity and Metabolism 20 (7), 1793-1797, 2018 | 76 | 2018 |
Gestational diabetes impairs human fetal postprandial brain activity K Linder, F Schleger, I Kiefer-Schmidt, L Fritsche, S Kümmel, M Heni, ... The Journal of Clinical Endocrinology & Metabolism 100 (11), 4029-4036, 2015 | 68 | 2015 |
Maternal insulin sensitivity is associated with oral glucose-induced changes in fetal brain activity K Linder, F Schleger, C Ketterer, L Fritsche, I Kiefer-Schmidt, A Hennige, ... Diabetologia 57, 1192-1198, 2014 | 60 | 2014 |
Empagliflozin improves insulin sensitivity of the hypothalamus in humans with prediabetes: a randomized, double-blind, placebo-controlled, phase 2 trial S Kullmann, J Hummel, R Wagner, C Dannecker, A Vosseler, L Fritsche, ... Diabetes Care 45 (2), 398-406, 2022 | 56 | 2022 |
Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin L Stirm, P Huypens, S Sass, R Batra, L Fritsche, S Brucker, H Abele, ... Scientific reports 8 (1), 1366, 2018 | 53 | 2018 |
Insulin-induced serine phosphorylation of IRS-2 via ERK1/2 and mTOR: studies on the function of Ser675 and Ser907 L Fritsche, SS Neukamm, R Lehmann, E Kremmer, AM Hennige, ... American Journal of Physiology-Endocrinology and Metabolism 300 (5), E824-E836, 2011 | 53 | 2011 |
Activation of the mitogen-activated protein kinase (MAPK) signalling pathway in the liver of mice is related to plasma glucose levels after acute exercise M Hoene, H Franken, L Fritsche, R Lehmann, AK Pohl, HU Häring, A Zell, ... Diabetologia 53, 1131-1141, 2010 | 51 | 2010 |
Different effects of lifestyle intervention in high-and low-risk prediabetes: results of the randomized controlled prediabetes lifestyle intervention study (PLIS) A Fritsche, R Wagner, M Heni, K Kantartzis, J Machann, F Schick, ... Diabetes 70 (12), 2785-2795, 2021 | 50 | 2021 |
Gestational diabetes alters the fetal heart rate variability during an oral glucose tolerance test: a fetal magnetocardiography study E Fehlert, K Willmann, L Fritsche, K Linder, H Mat‐Husin, F Schleger, ... BJOG: An International Journal of Obstetrics & Gynaecology 124 (12), 1891-1898, 2017 | 43 | 2017 |
IL-6 deficiency in mice neither impairs induction of metabolic genes in the liver nor affects blood glucose levels during fasting and moderately intense exercise L Fritsche, M Hoene, R Lehmann, H Ellingsgaard, AM Hennige, AK Pohl, ... Diabetologia 53, 1732-1742, 2010 | 43 | 2010 |
Quality control of serum and plasma by quantification of (4E, 14Z)-sphingadienine-C18-1-phosphate uncovers common preanalytical errors during handling of whole blood X Liu, M Hoene, P Yin, L Fritsche, P Plomgaard, JS Hansen, CT Nakas, ... Clinical chemistry 64 (5), 810-819, 2018 | 38 | 2018 |
A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation R Wagner, L Fritsche, M Heni, E Fehlert, N Stefan, H Staiger, HU Häring, ... Acta diabetologica 53, 1037-1044, 2016 | 37 | 2016 |
Androgen receptor overexpression in prostate cancer in type 2 diabetes SZ Lutz, J Hennenlotter, MO Scharpf, C Sailer, L Fritsche, V Schmid, ... Molecular metabolism 8, 158-166, 2018 | 36 | 2018 |
BMI-independent effects of gestational diabetes on human placenta L Stirm, M Kovářová, S Perschbacher, R Michlmaier, L Fritsche, ... The Journal of Clinical Endocrinology & Metabolism 103 (9), 3299-3309, 2018 | 35 | 2018 |
Non-alcoholic fatty liver disease and impaired proinsulin conversion as newly identified predictors of the long-term non-response to a lifestyle intervention for diabetes … V Schmid, R Wagner, C Sailer, L Fritsche, K Kantartzis, A Peter, M Heni, ... Diabetologia 60, 2341-2351, 2017 | 31 | 2017 |
Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin M Keuper, L Berti, B Raedle, S Sachs, A Böhm, L Fritsche, A Fritsche, ... Molecular Metabolism 20, 28-37, 2019 | 19 | 2019 |
Olive oil aroma extract modulates cerebral blood flow in gustatory brain areas in humans S Frank, K Linder, L Fritsche, MA Hege, S Kullmann, A Krzeminski, ... The American journal of clinical nutrition 98 (5), 1360-1366, 2013 | 19 | 2013 |
Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese S Kullmann, T Goj, R Veit, L Fritsche, L Wagner, P Schneeweiss, ... JCI insight 7 (18), 2022 | 18 | 2022 |