Paul A. Spagnuolo
Paul A. Spagnuolo
University of Guelph
Verified email at uwaterloo.ca - Homepage
TitleCited byYear
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia
M Škrtić, S Sriskanthadevan, B Jhas, M Gebbia, X Wang, Z Wang, ...
Cancer cell 20 (5), 674-688, 2011
3412011
A possible structure of the casein micelle based on high-resolution field-emission scanning electron microscopy
DG Dalgleish, PA Spagnuolo, HD Goff
International Dairy Journal 14 (12), 1025-1031, 2004
2192004
Kappa-carrageenan interactions in systems containing casein micelles and polysaccharide stabilizers
PA Spagnuolo, DG Dalgleish, HD Goff, ER Morris
Food Hydrocolloids 19 (3), 371-377, 2005
1762005
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RPS Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
1592014
The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma
PA Spagnuolo, J Hu, R Hurren, X Wang, M Gronda, MA Sukhai, A Di Meo, ...
Blood 115 (23), 4824-4833, 2010
982010
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors
MA Sukhai, S Prabha, R Hurren, AC Rutledge, AY Lee, ...
The Journal of clinical investigation 123 (1), 2012
812012
Targeting mitochondria with avocatin B induces selective leukemia cell death
EA Lee, L Angka, SG Rota, T Hanlon, A Mitchell, R Hurren, XM Wang, ...
Cancer research 75 (12), 2478-2488, 2015
662015
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway
X Mao, B Cao, TE Wood, R Hurren, J Tong, X Wang, W Wang, J Li, Y Jin, ...
Blood 117 (6), 1986-1997, 2011
562011
Repeated exercise in mice alters expression of IL-10 and TNF-α in intestinal lymphocytes
L Hoffman-Goetz, PA Spagnuolo, J Guan
Brain, behavior, and immunity 22 (2), 195-199, 2008
512008
New sources of drugs for hematologic malignancies
MA Sukhai, PA Spagnuolo, S Weir, J Kasper, L Patton, AD Schimmer
Blood 117 (25), 6747-6755, 2011
392011
Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide’s anti-leukemic activity
PA Spagnuolo, R Hurren, M Gronda, N MacLean, A Datti, A Basheer, ...
Leukemia 27 (6), 1236, 2013
352013
Effect of repeated exercise stress on caspase 3, Bcl-2, HSP 70 and CuZn-SOD protein expression in mouse intestinal lymphocytes
L Hoffman-Goetz, PA Spagnuolo
Journal of neuroimmunology 187 (1-2), 94-101, 2007
332007
Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against …
BDG Page, DC Croucher, ZH Li, S Haftchenary, VH Jimenez-Zepeda, ...
Journal of medicinal chemistry 56 (18), 7190-7200, 2013
292013
DNA ministrings: highly safe and effective gene delivery vectors
N Nafissi, S Alqawlaq, EA Lee, M Foldvari, PA Spagnuolo, RA Slavcev
Molecular Therapy-Nucleic Acids 3, e165, 2014
212014
Effect of short-term dietary intake of bovine lactoferrin on intestinal lymphocyte apoptosis in healthy mice
PA Spagnuolo, RP Bird, L Hoffman-Goetz
Nutrition 23 (11-12), 812-817, 2007
202007
ORIGINAL PAPERS-Effect of stabilizers on fat destabilization measurements in ice cream
HD Goff, P Spagnuolo
Milchwissenschaft 56 (8), 450-453, 2001
202001
Glucopsychosine increases cytosolic calcium to induce calpain-mediated apoptosis of acute myeloid leukemia cells
L Angka, EA Lee, SG Rota, T Hanlon, M Sukhai, M Minden, EM McMillan, ...
Cancer letters 348 (1-2), 29-37, 2014
192014
Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26
MJ Cutler, EL Lowthers, CL Richard, DM Hajducek, PA Spagnuolo, J Blay
BMC cancer 15 (1), 882, 2015
152015
Mitochondrial DNA damage by bleomycin induces AML cell death
MT Yeung, R Hurren, C Nemr, X Wang, S Hershenfeld, M Gronda, ...
Apoptosis 20 (6), 811-820, 2015
142015
Estrogen receptor β is a novel target in acute myeloid leukemia
SG Rota, A Roma, I Dude, C Ma, R Stevens, J MacEachern, J Graczyk, ...
Molecular cancer therapeutics 16 (11), 2618-2626, 2017
132017
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