Crystal structure of the Src family tyrosine kinase Hck F Sicheri, I Moarefi, J Kuriyan Nature 385 (6617), 602-609, 1997 | 1348 | 1997 |
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication P Nash, X Tang, S Orlicky, Q Chen, FB Gertler, MD Mendenhall, F Sicheri, ... Nature 414 (6863), 514-521, 2001 | 831 | 2001 |
Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement I Moarefi, M LaFevre-Bernt, F Sicheri, M Huse, CH Lee, J Kuriyan, ... Nature 385 (6617), 650-653, 1997 | 713 | 1997 |
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase S Orlicky, X Tang, A Willems, M Tyers, F Sicheri Cell 112 (2), 243-256, 2003 | 536 | 2003 |
Bone recognition mechanism of porcine osteocalcin from crystal structure QQ Hoang, F Sicheri, AJ Howard, DSC Yang Nature 425 (6961), 977-980, 2003 | 524 | 2003 |
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark A Fradet-Turcotte, MD Canny, C Escribano-Díaz, A Orthwein, CCY Leung, ... Nature 499 (7456), 50-54, 2013 | 497 | 2013 |
Crystal structure of Hck in complex with a Src family–selective tyrosine kinase inhibitor T Schindler, F Sicheri, A Pico, A Gazit, A Levitzki, J Kuriyan Molecular cell 3 (5), 639-648, 1999 | 480 | 1999 |
Structures of Src-family tyrosine kinases F Sicheri, J Kuriyan Current opinion in structural biology 7 (6), 777-785, 1997 | 462 | 1997 |
Ice-binding structure and mechanism of an antifreeze protein from winter flounder F Sicheri, DSC Yang Nature 375 (6530), 427-431, 1995 | 441 | 1995 |
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region LE Wybenga-Groot, B Baskin, SH Ong, J Tong, T Pawson, F Sicheri Cell 106 (6), 745-757, 2001 | 402 | 2001 |
A dimerization-dependent mechanism drives RAF catalytic activation T Rajakulendran, M Sahmi, M Lefrançois, F Sicheri, M Therrien Nature 461 (7263), 542-545, 2009 | 398 | 2009 |
Higher-order substrate recognition of eIF2α by the RNA-dependent protein kinase PKR AC Dar, TE Dever, F Sicheri Cell 122 (6), 887-900, 2005 | 376 | 2005 |
Mechanistic link between PKR dimerization, autophosphorylation, and eIF2α substrate recognition M Dey, C Cao, AC Dar, T Tamura, K Ozato, F Sicheri, TE Dever Cell 122 (6), 901-913, 2005 | 341 | 2005 |
Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing KPK Lee, M Dey, D Neculai, C Cao, TE Dever, F Sicheri Cell 132 (1), 89-100, 2008 | 321 | 2008 |
Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions AL Couzens, JDR Knight, MJ Kean, G Teo, A Weiss, WH Dunham, ZY Lin, ... Science signaling 6 (302), rs15-rs15, 2013 | 311 | 2013 |
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 S Nakada, I Tai, S Panier, A Al-Hakim, S Iemura, YC Juang, L O’Donnell, ... Nature 466 (7309), 941-946, 2010 | 305 | 2010 |
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain AA Ogunjimi, DJ Briant, N Pece-Barbara, C Le Roy, GM Di Guglielmo, ... Molecular cell 19 (3), 297-308, 2005 | 300 | 2005 |
Formin leaky cap allows elongation in the presence of tight capping proteins SH Zigmond, M Evangelista, C Boone, C Yang, AC Dar, F Sicheri, ... Current Biology 13 (20), 1820-1823, 2003 | 299 | 2003 |
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3 … M Goudreault, LM D'Ambrosio, MJ Kean, MJ Mullin, BG Larsen, ... Molecular & Cellular Proteomics 8 (1), 157-171, 2009 | 297 | 2009 |
The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization D Stapleton, I Balan, T Pawson, F Sicheri Nature structural biology 6 (1), 44-49, 1999 | 294 | 1999 |