Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7 V Hornung, M Guenthner-Biller, C Bourquin, A Ablasser, M Schlee, ... Nature medicine 11 (3), 263-270, 2005 | 1756 | 2005 |
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation Y Yan, W Jiang, T Spinetti, A Tardivel, R Castillo, C Bourquin, G Guarda, ... Immunity 38 (6), 1154-1163, 2013 | 768 | 2013 |
Cellular immunostimulation by CpG-sequence-coated DNA origami structures VJ Schuller, S Heidegger, N Sandholzer, PC Nickels, NA Suhartha, ... ACS nano 5 (12), 9696-9702, 2011 | 518 | 2011 |
5′-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma H Poeck, R Besch, C Maihoefer, M Renn, D Tormo, SS Morskaya, ... Nature medicine 14 (11), 1256-1263, 2008 | 496 | 2008 |
CpG blocks immunosuppression by myeloid-derived suppressor cells in tumor-bearing mice C Zoglmeier, H Bauer, D Nörenberg, G Wedekind, P Bittner, ... Clinical Cancer Research 17 (7), 1765-1775, 2011 | 293 | 2011 |
Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing F Haasters, WC Prall, D Anz, C Bourquin, C Pautke, S Endres, ... Journal of anatomy 214 (5), 759-767, 2009 | 207 | 2009 |
CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes M Rapp, MWM Wintergerst, WG Kunz, VK Vetter, MML Knott, D Lisowski, ... Journal of Experimental Medicine 216 (5), 1170-1181, 2019 | 188 | 2019 |
Myelin oligodendrocyte glycoprotein induces experimental autoimmune encephalomyelitis in the “resistant” Brown Norway rat: disease susceptibility is determined by MHC and MHC … A Stefferl, U Brehm, M Storch, D Lambracht-Washington, C Bourquin, ... The Journal of Immunology 163 (1), 40-49, 1999 | 185 | 1999 |
Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells T Vollbrecht, R Stirner, A Tufman, J Roider, RM Huber, JR Bogner, ... Aids 26 (12), F31-F37, 2012 | 176 | 2012 |
Targeting CpG oligonucleotides to the lymph node by nanoparticles elicits efficient antitumoral immunity C Bourquin, D Anz, K Zwiorek, AL Lanz, S Fuchs, S Weigel, ... The Journal of Immunology 181 (5), 2990-2998, 2008 | 174 | 2008 |
Delivery by cationic gelatin nanoparticles strongly increases the immunostimulatory effects of CpG oligonucleotides K Zwiorek, C Bourquin, J Battiany, G Winter, S Endres, G Hartmann, ... Pharmaceutical research 25, 551-562, 2008 | 170 | 2008 |
ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells P Duewell, U Kisser, K Heckelsmiller, S Hoves, P Stoitzner, S Koernig, ... The Journal of Immunology 187 (1), 55-63, 2011 | 141 | 2011 |
CD103 is a hallmark of tumor‐infiltrating regulatory T cells D Anz, W Mueller, M Golic, WG Kunz, M Rapp, VH Koelzer, J Ellermeier, ... International journal of cancer 129 (10), 2417-2426, 2011 | 133 | 2011 |
Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes A Ablasser, H Poeck, D Anz, M Berger, M Schlee, S Kim, C Bourquin, ... The Journal of Immunology 182 (11), 6824-6833, 2009 | 133 | 2009 |
Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis KB Abdul‐Majid, A Stefferl, C Bourquin, H Lassmann, C Linington, ... Scandinavian journal of immunology 55 (1), 70-81, 2002 | 130 | 2002 |
Mesoporous silica nanoparticles as pH-responsive carrier for the immune-activating drug resiquimod enhance the local immune response in mice J Wagner, D Gößl, N Ustyanovska, M Xiong, D Hauser, O Zhuzhgova, ... ACS nano 15 (3), 4450-4466, 2021 | 123 | 2021 |
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery S Heidegger, D Gößl, A Schmidt, S Niedermayer, C Argyo, S Endres, ... Nanoscale 8 (2), 938-948, 2016 | 115 | 2016 |
Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance C Bourquin, C Hotz, D Noerenberg, A Voelkl, S Heidegger, LC Roetzer, ... Cancer research 71 (15), 5123-5133, 2011 | 99 | 2011 |
Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytotoxic T-cell and IgG2a response C Bourquin, L Schmidt, V Hornung, C Wurzenberger, D Anz, ... Blood 109 (7), 2953-2960, 2007 | 99 | 2007 |
TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function T Spinetti, L Spagnuolo, I Mottas, C Secondini, M Treinies, C Rüegg, ... Oncoimmunology 5 (11), e1230578, 2016 | 94 | 2016 |