Alexander D Gitlin, MD, PhD
Alexander D Gitlin, MD, PhD
Assistant Member, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center
Verified email at - Homepage
Cited by
Cited by
Clonal selection in the germinal centre by regulated proliferation and hypermutation
AD Gitlin, Z Shulman, MC Nussenzweig
Nature 509 (7502), 637-640, 2014
A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center
TA Schwickert, GD Victora, DR Fooksman, AO Kamphorst, MR Mugnier, ...
Journal of Experimental Medicine 208 (6), 1243-1252, 2011
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching
M Di Virgilio, E Callen, A Yamane, W Zhang, M Jankovic, AD Gitlin, ...
Science 339 (6120), 711-715, 2013
Dynamic signaling by T follicular helper cells during germinal center B cell selection
Z Shulman, AD Gitlin, JS Weinstein, B Lainez, E Esplugues, RA Flavell, ...
Science 345 (6200), 1058-1062, 2014
T follicular helper cell dynamics in germinal centers
Z Shulman, AD Gitlin, S Targ, M Jankovic, G Pasqual, MC Nussenzweig, ...
Science 341 (6146), 673-677, 2013
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies
JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ...
Immunity 45 (3), 483-496, 2016
Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice
A Escolano, JM Steichen, P Dosenovic, DW Kulp, J Golijanin, D Sok, ...
Cell 166 (6), 1445-1458. e12, 2016
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
JA Horwitz, A Halper-Stromberg, H Mouquet, AD Gitlin, A Tretiakova, ...
Proceedings of the National Academy of Sciences 110 (41), 16538-16543, 2013
Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice
P Dosenovic, L von Boehmer, A Escolano, J Jardine, NT Freund, AD Gitlin, ...
Cell 161 (7), 1505-1515, 2015
T cell help controls the speed of the cell cycle in germinal center B cells
AD Gitlin, CT Mayer, TY Oliveira, Z Shulman, MJK Jones, A Koren, ...
Science 349 (6248), 643-646, 2015
The microanatomic segregation of selection by apoptosis in the germinal center
CT Mayer, A Gazumyan, EE Kara, AD Gitlin, J Golijanin, C Viant, J Pai, ...
Science 358 (6360), eaao2602, 2017
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine
C Li, A Lee, L Grigoryan, PS Arunachalam, MKD Scott, M Trisal, ...
Nature immunology 23 (4), 543-555, 2022
Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
AT McGuire, MD Gray, P Dosenovic, AD Gitlin, NT Freund, J Petersen, ...
Nature communications 7 (1), 10618, 2016
Sequencing and cloning of antigen-specific antibodies from mouse memory B cells
L Von Boehmer, C Liu, S Ackerman, AD Gitlin, Q Wang, A Gazumyan, ...
Nature protocols 11 (10), 1908-1923, 2016
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
M Medina-Ramírez, F Garces, A Escolano, P Skog, SW de Taeye, ...
Journal of Experimental Medicine 214 (9), 2573-2590, 2017
Independent roles of switching and hypermutation in the development and persistence of B lymphocyte memory
AD Gitlin, L von Boehmer, A Gazumyan, Z Shulman, TY Oliveira, ...
Immunity 44 (4), 769-781, 2016
ICAMs support B cell interactions with T follicular helper cells and promote clonal selection
I Zaretsky, O Atrakchi, RD Mazor, L Stoler-Barak, A Biram, SW Feigelson, ...
Journal of Experimental Medicine 214 (11), 3435-3448, 2017
Integration of innate immune signalling by caspase-8 cleavage of N4BP1
AD Gitlin, K Heger, AF Schubert, R Reja, D Yan, VC Pham, E Suto, ...
Nature 587 (7833), 275-280, 2020
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway
EH Kim, MC Woodruff, L Grigoryan, B Maier, SH Lee, P Mandal, ...
Elife 9, e52687, 2020
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells
S Kubicek, JC Gilbert, D Fomina-Yadlin, AD Gitlin, Y Yuan, FF Wagner, ...
Proceedings of the National Academy of Sciences 109 (14), 5364-5369, 2012
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