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J. Agustin Cruz
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IL-17 receptor signaling in oral epithelial cells is critical for protection against oropharyngeal candidiasis
HR Conti, VM Bruno, EE Childs, S Daugherty, JP Hunter, BG Mengesha, ...
Cell host & microbe 20 (5), 606-617, 2016
1702016
MCPIP1 endoribonuclease activity negatively regulates interleukin-17-mediated signaling and inflammation
AV Garg, N Amatya, K Chen, JA Cruz, P Grover, N Whibley, HR Conti, ...
Immunity 43 (3), 475-487, 2015
1502015
IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a
N Amatya, EE Childs, JA Cruz, FEY Aggor, AV Garg, AJ Berman, ...
Science Signaling 11 (551), eaat4617, 2018
612018
Chronic hypoxia induces right heart failure in caveolin-1−/− mice
JA Cruz, EM Bauer, AI Rodriguez, A Gangopadhyay, NS Zeineh, Y Wang, ...
American Journal of Physiology-Heart and Circulatory Physiology 302 (12 …, 2012
452012
Sex-, stress-, and sympathetic post-ganglionic-dependent changes in identity and proportions of immune cells in the dura
LA McIlvried, JA Cruz, LA Borghesi, MS Gold
Cephalalgia 37 (1), 36-48, 2017
342017
CCAAT/Enhancer-binding protein β promotes pathogenesis of EAE
MR Simpson-Abelson, G Hernandez-Mir, EE Childs, JA Cruz, AC Poholek, ...
Cytokine 92, 24-32, 2017
302017
A network-centric approach to drugging TNF-induced NF-κB signaling
NA Pabon, Q Zhang, JA Cruz, DL Schipper, CJ Camacho, REC Lee
Nature communications 10 (1), 860, 2019
282019
IL-17 signaling triggers degradation of the constitutive NF-κB inhibitor ABIN-1
JA Cruz, EE Childs, N Amatya, AV Garg, R Beyaert, LP Kane, ...
Immunohorizons 1 (7), 133-141, 2017
242017
A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB
JA Cruz, CS Mokashi, GJ Kowalczyk, Y Guo, Q Zhang, S Gupta, ...
Science Advances 7 (30), eabi9410, 2021
132021
dNEMO: a tool for quantification of mRNA and punctate structures in time-lapse images of single cells
GJ Kowalczyk, JA Cruz, Y Guo, Q Zhang, N Sauerwald, REC Lee
Bioinformatics 37 (5), 677-683, 2021
62021
Stochastic pooling of IKK/NEMO complexes describes information transmission in the NF-KB pathway in response to IL-1 and TNF stimulation.
JA Cruz, C Mokashi, REC Lee
The Journal of Immunology 206 (1_Supplement), 106.07-106.07, 2021
12021
Arid5a orchestrates IL-17-mediated inflammation through post-transcriptional control of mRNA
N Amatya, JA Cruz, F Aggor, A Garg, AJ Berman, U Atasoy, SL Gaffen
The Journal of Immunology 200 (1_Supplement), 164.4-164.4, 2018
12018
MCPIP1/Regnase is a negative feedback inhibitor of IL-17-mediated signaling and inflammation (CCR3P. 200)
S Gaffen, A Garg, N Amatya, K Chen, J Cruz, P Grover, N Whibley, ...
The Journal of Immunology 194 (1_Supplement), 49.1-49.1, 2015
12015
Decoding patterns of macrophage TNF production to model NF-κB dynamics and cell-cell communication
JA Cruz, RA Gottschalk, REC Lee
The Journal of Immunology 204 (1_Supplement), 60.20-60.20, 2020
2020
IL-17 signaling inducibly degrades ABIN1, a constitutive inhibitor of inflammatory signaling
JA Cruz, E Childs, N Amatya, M Simpson-Abelson, A Garg, R Beyaert, ...
The Journal of Immunology 198 (1_Supplement), 61.3-61.3, 2017
2017
Functional Regulation of Interleukin-17 Receptor Signaling
JA Cruz
University of Pittsburgh, 2017
2017
Abin1 Inhibits Il-17r Signaling In An A20-independent Manner
JA Cruz, MR Simpson-Abelson, A Garg, N Amatya, A Ma, R Beyaert, ...
Cytokine 87, 106, 2016
2016
ID: 36: MCPIP1/Regnase-1 is a negative feedback inhibitor regulating IL-17 signaling and inflammation
A Garg, N Amatya, K Chen, JA Cruz, P Grover, N Whibley, HR Conti, ...
Cytokine 76 (1), 70, 2015
2015
ID: 179: ABIN1 inhibits IL-17 signaling in a feedback manner
JA Cruz, AV Garg, N Amatya, A Ma, SL Gaffen
Cytokine 76 (1), 97, 2015
2015
DNA damage in hematopoietic stem cells as a mechanism for lymphoid progenitor exhaustion in E47 deficient mice (111.20)
JA Cruz, L Borghesi
The Journal of Immunology 188 (1_Supplement), 111.20-111.20, 2012
2012
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Artiklar 1–20