Följ
Danchen Wu
Danchen Wu
Andra namn吴 丹辰, Dan-Chen Wu
Verifierad e-postadress på queensu.ca
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Hypoxic pulmonary vasoconstriction: from molecular mechanisms to medicine
KJ Dunham-Snary, D Wu, EA Sykes, A Thakrar, LRG Parlow, JD Mewburn, ...
Chest 151 (1), 181-192, 2017
4152017
MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype
Z Hong, KH Chen, A DasGupta, F Potus, K Dunham-Snary, S Bonnet, ...
American journal of respiratory and critical care medicine 195 (4), 515-529, 2017
1452017
Epigenetic dysregulation of the dynamin-related protein 1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension …
KH Chen, A Dasgupta, J Lin, F Potus, S Bonnet, J Iremonger, J Fu, ...
Circulation 138 (3), 287-304, 2018
1232018
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension
L Tian, M Neuber-Hess, J Mewburn, A Dasgupta, K Dunham-Snary, D Wu, ...
Journal of molecular medicine 95, 381-393, 2017
992017
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial …
L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ...
Circulation research 126 (12), 1723-1745, 2020
902020
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
P Romani, N Nirchio, M Arboit, V Barbieri, A Tosi, F Michielin, S Shibuya, ...
Nature cell biology 24 (2), 168-180, 2022
842022
Ndufs2, a core subunit of mitochondrial complex I, is essential for acute oxygen-sensing and hypoxic pulmonary vasoconstriction
KJ Dunham-Snary, D Wu, F Potus, EA Sykes, JD Mewburn, RL Charles, ...
Circulation research 124 (12), 1727-1746, 2019
782019
Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
D Wu, A Dasgupta, KH Chen, M Neuber‐Hess, J Patel, TE Hurst, ...
The FASEB Journal 34 (1), 1447-1464, 2020
742020
Increased Drp1-mediated mitochondrial fission promotes proliferation and collagen production by right ventricular fibroblasts in experimental pulmonary arterial hypertension
L Tian, F Potus, D Wu, A Dasgupta, KH Chen, J Mewburn, P Lima, ...
Frontiers in physiology 9, 369543, 2018
712018
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension
YF Fan, R Zhang, X Jiang, L Wen, DC Wu, D Liu, P Yuan, YL Wang, ...
Cardiovascular research 99 (3), 395-403, 2013
652013
Colchicine depolymerizes microtubules, increases junctophilin‐2, and improves right ventricular function in experimental pulmonary arterial hypertension
KW Prins, L Tian, D Wu, T Thenappan, JM Metzger, SL Archer
Journal of the American Heart Association 6 (6), e006195, 2017
582017
Mitochondria in the pulmonary vasculature in health and disease: oxygen-sensing, metabolism, and dynamics
A Dasgupta, D Wu, L Tian, PY Xiong, KJ Dunham-Snary, KH Chen, ...
Comprehensive physiology 10 (2), 713-765, 2020
472020
Identifying microRNAs targeting Wnt/β-catenin pathway in end-stage idiopathic pulmonary arterial hypertension
D Wu, CCJ Talbot, Q Liu, ZC Jing, RL Damico, R Tuder, KC Barnes, ...
J Mol Med (Berl), 2016
472016
Effects of Pinus massoniana bark extract on the adhesion and migration capabilities of HeLa cells
DC Wu, S Li, DQ Yang, YY Cui
Fitoterapia 82 (8), 1202-1205, 2011
462011
Macrophage–NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension
R Al-Qazazi, PDA Lima, SZ Prisco, F Potus, A Dasgupta, KH Chen, L Tian, ...
American journal of respiratory and critical care medicine 206 (5), 608-624, 2022
402022
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer
D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ...
Free Radical Biology and Medicine 170, 150-178, 2021
372021
Clinical value of non-coding RNAs in cardiovascular, pulmonary, and muscle diseases
S Bonnet, O Boucherat, R Paulin, D Wu, CCT Hindmarch, SL Archer, ...
American Journal of Physiology-Cell Physiology 318 (1), C1-C28, 2020
352020
PINK1 induced phosphorylation of mitofusin 2 (Mfn2) at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial …
A Dasgupta, KH Chen, PDA Lima, J Mewburn, D Wu, R Al-Qazazi, ...
FASEB journal: official publication of the Federation of American Societies …, 2021
282021
SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia
SL Archer, A Dasgupta, KH Chen, D Wu, K Baid, JE Mamatis, V Gonzalez, ...
Redox Biology 58, 102508, 2022
202022
An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications
A Dasgupta, KH Chen, D Wu, V Hoskin, J Mewburn, PDA Lima, ...
The FASEB Journal 34 (4), 5106-5127, 2020
202020
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