| Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis EA Bard-Chapeau, S Li, J Ding, SS Zhang, HH Zhu, F Princen, DD Fang, ... Cancer cell 19 (5), 629-639, 2011 | 347 | 2011 |
| TRIM59 is up-regulated in gastric tumors, promoting ubiquitination and degradation of p53 Z Zhou, Z Ji, Y Wang, J Li, H Cao, HH Zhu, WQ Gao Gastroenterology 147 (5), 1043-1054, 2014 | 178 | 2014 |
| Integrative pathway enrichment analysis of multivariate omics data M Paczkowska, J Barenboim, N Sintupisut, NS Fox, H Zhu, D Abd-Rabbo, ... Nature communications 11 (1), 735, 2020 | 136 | 2020 |
| WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells K Zhang, Y Guo, X Wang, H Zhao, Z Ji, C Cheng, L Li, Y Fang, D Xu, ... Cancer research 77 (9), 2534-2547, 2017 | 132 | 2017 |
| Tyrosine phosphatase SHP-2 mediates C-type lectin receptor–induced activation of the kinase Syk and anti-fungal TH17 responses Z Deng, S Ma, H Zhou, A Zang, Y Fang, T Li, H Shi, M Liu, M Du, ... Nature immunology 16 (6), 642-652, 2015 | 113 | 2015 |
| Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool HH Zhu, K Ji, N Alderson, Z He, S Li, W Liu, DE Zhang, L Li, GS Feng Blood, The Journal of the American Society of Hematology 117 (20), 5350-5361, 2011 | 100 | 2011 |
| Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth W Li, Y He, J Yang, G Hu, Y Lin, T Ran, B Peng, B Xie, M Huang, X Gao, ... Nature communications 12 (1), 1946, 2021 | 95 | 2021 |
| Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesis S Li, DDF Hsu, B Li, X Luo, N Alderson, L Qiao, L Ma, HH Zhu, Z He, ... Cell metabolism 20 (2), 320-332, 2014 | 94 | 2014 |
| Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer B Dong, J Miao, Y Wang, W Luo, Z Ji, H Lai, M Zhang, X Cheng, J Wang, ... Communications biology 3 (1), 778, 2020 | 93 | 2020 |
| T lymphocyte membrane-decorated epigenetic nanoinducer of interferons for cancer immunotherapy Y Zhai, J Wang, T Lang, Y Kong, R Rong, Y Cai, W Ran, F Xiong, C Zheng, ... Nature Nanotechnology 16 (11), 1271-1280, 2021 | 83 | 2021 |
| Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages J Wang, HH Zhu, M Chu, Y Liu, C Zhang, G Liu, X Yang, R Yang, WQ Gao Nature communications 5 (1), 4758, 2014 | 83 | 2014 |
| Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals Z He, SS Zhang, Q Meng, S Li, HH Zhu, MA Raquil, N Alderson, H Zhang, ... Molecular and cellular biology 32 (10), 1867-1878, 2012 | 71 | 2012 |
| Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition K Zhang, H Zhao, Z Ji, C Zhang, P Zhou, L Wang, Q Chen, J Wang, ... Oncogene 35 (10), 1271-1282, 2016 | 69 | 2016 |
| Candidate cancer driver mutations in distal regulatory elements and long-range chromatin interaction networks H Zhu, L Uusküla-Reimand, K Isaev, L Wadi, A Alizada, S Shuai, V Huang, ... Molecular cell 77 (6), 1307-1321. e10, 2020 | 66 | 2020 |
| A Src family kinase–Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation H Huang, AJ Woo, Z Waldon, Y Schindler, TB Moran, HH Zhu, GS Feng, ... Genes & development 26 (14), 1587-1601, 2012 | 64 | 2012 |
| Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration Y Shao, XB Wang, JJ Zhang, ML Li, SS Wu, XY Ma, X Wang, HF Zhao, ... Nature communications 11 (1), 1-15, 2020 | 62 | 2020 |
| The transcriptional landscape of Shh medulloblastoma P Skowron, H Farooq, FMG Cavalli, AS Morrissy, M Ly, LD Hendrikse, ... Nature communications 12 (1), 1749, 2021 | 61 | 2021 |
| E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo X Wang, B Dong, K Zhang, Z Ji, C Cheng, H Zhao, Y Sheng, X Li, L Fan, ... PLoS genetics 14 (8), e1007609, 2018 | 61 | 2018 |
| Nonreceptor tyrosine phosphatase Shp2 promotes adipogenesis through inhibition of p38 MAP kinase Z He, HH Zhu, TJ Bauler, J Wang, T Ciaraldi, N Alderson, S Li, MA Raquil, ... Proceedings of the National Academy of Sciences 110 (1), E79-E88, 2013 | 59 | 2013 |
| miR-302/367/LATS2/YAP pathway is essential for prostate tumor-propagating cells and promotes the development of castration resistance Y Guo, J Cui, Z Ji, C Cheng, K Zhang, C Zhang, M Chu, Q Zhao, Z Yu, ... Oncogene 36 (45), 6336-6347, 2017 | 54 | 2017 |
