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Pau Creixell
Pau Creixell
Koch Institute for Integrative Cancer Research at MIT
Verifierad e-postadress på mit.edu
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Pathway and network analysis of cancer genomes
Nature methods 12 (7), 615-621, 2015
3752015
Computational approaches to identify functional genetic variants in cancer genomes
Nature methods 10 (8), 723-729, 2013
1892013
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling
P Creixell, EM Schoof, CD Simpson, J Longden, CJ Miller, HJ Lou, ...
Cell 163 (1), 202-217, 2015
1832015
Navigating cancer network attractors for tumor-specific therapy
P Creixell, EM Schoof, JT Erler, R Linding
Nature biotechnology 30 (9), 842-848, 2012
1532012
Exploiting temporal collateral sensitivity in tumor clonal evolution
B Zhao, JC Sedlak, R Srinivas, P Creixell, JR Pritchard, B Tidor, ...
Cell 165 (1), 234-246, 2016
1422016
Unmasking determinants of specificity in the human kinome
P Creixell, A Palmeri, CJ Miller, HJ Lou, CC Santini, M Nielsen, BE Turk, ...
Cell 163 (1), 187-201, 2015
902015
Mutational properties of amino acid residues: implications for evolvability of phosphorylatable residues
P Creixell, EM Schoof, CSH Tan, R Linding
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
592012
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
J So, A Pasculescu, AY Dai, K Williton, A James, V Nguyen, P Creixell, ...
Science signaling 8 (371), rs3-rs3, 2015
462015
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
B Van de Kooij, P Creixell, A van Vlimmeren, BA Joughin, CJ Miller, ...
Elife 8, e44635, 2019
432019
Cells, shared memory and breaking the PTM code
P Creixell, R Linding
Molecular systems biology 8 (1), 598, 2012
332012
Engineering allosteric regulation in protein kinases
D Pincus, JP Pandey, ZA Feder, P Creixell, O Resnekov, KA Reynolds
Science signaling 11 (555), eaar3250, 2018
252018
Personalized network‐based treatments in oncology
X Robin, P Creixell, O Radetskaya, CC Santini, J Longden, R Linding
Clinical Pharmacology & Therapeutics 94 (6), 646-650, 2013
252013
Hierarchical organization endows the kinase domain with regulatory plasticity
P Creixell, JP Pandey, A Palmeri, M Bhattacharyya, M Creixell, ...
Cell systems 7 (4), 371-383. e4, 2018
202018
Response to comment on “Positive selection of tyrosine loss in metazoan evolution”
CSH Tan, EM Schoof, P Creixell, A Pasculescu, WA Lim, T Pawson, ...
science 332 (6032), 917-917, 2011
192011
Global view of the RAF-MEK-ERK module and its immediate downstream effectors
CC Santini, J Longden, EM Schoof, CD Simpson, GR Jeschke, P Creixell, ...
Scientific Reports 9 (1), 10865, 2019
142019
CoreFlow: a computational platform for integration, analysis and modeling of complex biological data
A Pasculescu, EM Schoof, P Creixell, Y Zheng, M Olhovsky, R Tian, J So, ...
Journal of proteomics 100, 167-173, 2014
122014
The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks
B van de Kooij, FJ van der Wal, MB Rother, P Creixell, M Stout, ...
bioRxiv, 2023
22023
A dual histone code specifies the binding of heterochromatin protein Rhino to a subset of piRNA source loci
A Akkouche, E Kneuss, S Bornelöv, Y Renaud, EL Eastwood, J van Lopik, ...
bioRxiv, 2024.01. 11.575256, 2024
12024
Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations
M Creixell, SD Taylor, J Gerritsen, SY Bae, M Jiang, T Augustin, M Loui, ...
bioRxiv, 2023
2023
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Artiklar 1–19