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Arthur V. Hauenstein
Arthur V. Hauenstein
Janssen Biopharma
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
H Sharif, L Wang, WL Wang, VG Magupalli, L Andreeva, Q Qiao, ...
Nature 570 (7761), 338-343, 2019
5472019
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ...
Science 369 (6510), eaas8995, 2020
2462020
The NLRP3 inflammasome: Mechanism of action, role in disease and therapies
L Wang, AV Hauenstein
Molecular aspects of medicine 76, 100889, 2020
2422020
A Structural Basis for IκB Kinase 2 Activation Via Oligomerization-Dependent Trans Auto-Phosphorylation
S Polley, DB Huang, AV Hauenstein, AJ Fusco, X Zhong, D Vu, ...
PLoS biology 11 (6), e1001581, 2013
1192013
K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair
P Liu, W Gan, S Su, AV Hauenstein, T Fu, B Brasher, C Schwerdtfeger, ...
Science signaling 11 (533), eaar8133, 2018
982018
The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines
AV Hauenstein, L Zhang, H Wu
Current opinion in structural biology 31, 75-83, 2015
702015
X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster
CF Lee, AV Hauenstein, JK Fleming, WC Gasper, V Engelke, B Sankaran, ...
Structure 19 (3), 397-408, 2011
442011
Evidence for M1-linked polyubiquitin-mediated conformational change in NEMO
AV Hauenstein, G Xu, V Kabaleeswaran, H Wu
Journal of molecular biology 429 (24), 3793-3800, 2017
362017
Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics
J Sadek, MG Wuo, D Rooklin, A Hauenstein, SH Hong, A Gautam, H Wu, ...
Nature communications 11 (1), 1786, 2020
312020
Probing kinase activation and substrate specificity with an engineered monomeric IKK2
AV Hauenstein, WE Rogers, JD Shaul, DB Huang, G Ghosh, T Huxford
Biochemistry 53 (12), 2064-2073, 2014
112014
Full wwPDB X-ray Structure Validation Report i
H Wang, E Gouaux
Word wide protein data bank, 2009
22009
Crystal Structure of Drosophila Unc-45, a Putative Myosin Chaperone
CF Lee, AV Hauenstein, WC Gasper, B Sankaran, SI Bernstein, T Huxford
Biophysical Journal 98 (3), 34a, 2010
12010
Monomeric IKK: Probing activation and specificty
WE Rogers, A Hauenstein, T Huxford
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
A Structural Basis for IkB Kinase 2 Activation Via Oligomerization-Dependent Trans
S Polley, DB Huang, AV Hauenstein, AJ Fusco, X Zhong
2013
The Role of Oligomerization in Human IKK2 Activation as Revealed by Structural and Biophysical Studies
A Van Hauenstein
University of California, San Diego, 2013
2013
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