Chi Zhang
Chi Zhang
MIT Media Lab, McGovern Institute for Brain Research
Verifierad e-postadress på mit.edu - Startsida
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Organometallic palladium reagents for cysteine bioconjugation
EV Vinogradova, C Zhang, AM Spokoyny, BL Pentelute, SL Buchwald
Nature 526 (7575), 687-691, 2015
2682015
π-Clamp-mediated cysteine conjugation
C Zhang, M Welborn, T Zhu, NJ Yang, MS Santos, T Van Voorhis, ...
Nature chemistry 8 (2), 120-128, 2016
1542016
Rapid flow‐based peptide synthesis
MD Simon, PL Heider, A Adamo, AA Vinogradov, SK Mong, X Li, T Berger, ...
ChemBioChem 15 (5), 713-720, 2014
1022014
Convergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides
Y Zou, AM Spokoyny, C Zhang, MD Simon, H Yu, YS Lin, BL Pentelute
Organic & biomolecular chemistry 12 (4), 566-573, 2014
672014
Divergent unprotected peptide macrocyclisation by palladium-mediated cysteine arylation
AJ Rojas, C Zhang, EV Vinogradova, NH Buchwald, J Reilly, BL Pentelute, ...
Chemical science 8 (6), 4257-4263, 2017
662017
Arylation chemistry for bioconjugation
C Zhang, EV Vinogradova, AM Spokoyny, SL Buchwald, BL Pentelute
Angewandte Chemie International Edition 58 (15), 4810-4839, 2019
612019
Enzymatic “click” ligation: selective cysteine modification in polypeptides enabled by promiscuous glutathione S‐transferase
C Zhang, AM Spokoyny, Y Zou, MD Simon, BL Pentelute
Angewandte Chemie International Edition 52 (52), 14001-14005, 2013
532013
An umpolung approach for the chemoselective arylation of selenocysteine in unprotected peptides
DT Cohen, C Zhang, BL Pentelute, SL Buchwald
Journal of the American Chemical Society 137 (31), 9784-9787, 2015
462015
Enzyme-catalyzed macrocyclization of long unprotected peptides
C Zhang, P Dai, AM Spokoyny, BL Pentelute
Organic letters 16 (14), 3652-3655, 2014
462014
A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins
DT Cohen, C Zhang, CM Fadzen, AJ Mijalis, L Hie, KD Johnson, Z Shriver, ...
Nature chemistry 11 (1), 78-85, 2019
422019
Site‐Selective Cysteine–Cyclooctyne Conjugation
C Zhang, P Dai, AA Vinogradov, ZP Gates, BL Pentelute
Angewandte Chemie 130 (22), 6569-6573, 2018
332018
d-Amino Acid Scan of Two Small Proteins
MD Simon, Y Maki, AA Vinogradov, C Zhang, H Yu, YS Lin, Y Kajihara, ...
Journal of the American Chemical Society 138 (37), 12099-12111, 2016
272016
Salt effect accelerates site-selective cysteine bioconjugation
P Dai, C Zhang, M Welborn, JJ Shepherd, T Zhu, T Van Voorhis, ...
ACS central science 2 (9), 637-646, 2016
262016
Library design-facilitated high-throughput sequencing of synthetic peptide libraries
AA Vinogradov, ZP Gates, C Zhang, AJ Quartararo, KH Halloran, ...
ACS combinatorial science 19 (11), 694-701, 2017
222017
Amide-forming chemical ligation via O-acyl hydroxamic acids
DL Dunkelmann, Y Hirata, KA Totaro, DT Cohen, C Zhang, ZP Gates, ...
Proceedings of the National Academy of Sciences 115 (15), 3752-3757, 2018
162018
Expansion microscopy of C. elegans
CCJ Yu, NC Barry, AT Wassie, A Sinha, A Bhattacharya, S Asano, ...
Elife 9, e46249, 2020
142020
A structural and mechanistic study of π-clamp-mediated cysteine perfluoroarylation
P Dai, JK Williams, C Zhang, M Welborn, JJ Shepherd, T Zhu, ...
Scientific reports 7 (1), 1-11, 2017
102017
Modification of peptides via SNAr reactions of thiols with fluorinated aromatics
BL Pentelute, AM Spokoyny, Y Zou, C Zhang
US Patent 9,018,172, 2015
72015
DNA-directed formation of peptide bond: a model study toward DNA-programmed peptide ligation
C Zhang, Y Li, M Zhang, X Li
Tetrahedron 68 (26), 5152-5156, 2012
52012
Detection of bond formations by DNA-programmed chemical reactions and PCR amplification
Y Li, M Zhang, C Zhang, X Li
Chemical Communications 48 (76), 9513-9515, 2012
52012
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Artiklar 1–20