| Constitutively active mutants of the alpha 1B‐adrenergic receptor: role of highly conserved polar amino acids in receptor activation. A Scheer, F Fanelli, T Costa, PG De Benedetti, S Cotecchia The EMBO Journal 15 (14), 3566-3578, 1996 | 476 | 1996 |
| The activation process of the α1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate A Scheer, F Fanelli, T Costa, PG De Benedetti, S Cotecchia Proceedings of the National Academy of Sciences 94 (3), 808-813, 1997 | 271 | 1997 |
| Pharmacology of synthetic organic selenium compounds MJ Parnham, E Graf, VM Kolb, R Seth, S Sinha, RR Ruffolo, JP Hieble, ... Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des …, 1991 | 231 | 1991 |
| Computational modeling approaches to structure− function analysis of G protein-coupled receptors F Fanelli, PG De Benedetti Chemical reviews 105 (9), 3297-3351, 2005 | 180 | 2005 |
| Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the α1b-adrenergic receptor: effects on receptor isomerization and activation A Scheer, T Costa, F Fanelli, PG De Benedetti, S Mhaouty-Kodja, L Abuin, ... Molecular pharmacology 57 (2), 219-231, 2000 | 148 | 2000 |
| Activation mechanism of human oxytocin receptor: a combined study of experimental and computer-simulated mutagenesis F Fanelli, P Barbier, D Zanchetta, PG de Benedetti, B Chini Molecular Pharmacology 56 (1), 214-225, 1999 | 125 | 1999 |
| Electrostatic analysis and Brownian dynamics simulation of the association of plastocyanin and cytochrome f F De Rienzo, RR Gabdoulline, MC Menziani, PG De Benedetti, RC Wade Biophysical journal 81 (6), 3090-3104, 2001 | 110 | 2001 |
| Theoretical investigation of substrate specificity for cytochromes P450 IA2, P450 IID6 and P450 IIIA4 F De Rienzo, F Fanelli, MC Menziani, PG De Benedetti Journal of computer-aided molecular design 14, 93-116, 2000 | 103 | 2000 |
| Design, Synthesis, Structural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the … A Cappelli, G Pericot Mohr, A Gallelli, M Rizzo, M Anzini, S Vomero, ... Journal of medicinal chemistry 47 (10), 2574-2586, 2004 | 102 | 2004 |
| Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT3 Receptor Binding Site by … A Cappelli, M Anzini, S Vomero, L Mennuni, F Makovec, E Doucet, ... Journal of medicinal chemistry 41 (5), 728-741, 1998 | 97 | 1998 |
| Update 1 of: computational modeling approaches to structure–function analysis of G protein-coupled receptors F Fanelli, PG De Benedetti Chemical Reviews-Columbus 111 (12), PR438, 2011 | 95 | 2011 |
| Amino acids of the α 1B‐adrenergic receptor involved in agonist binding: differences in docking catecholamines to receptor subtypes A Cavalli, F Fanelli, C Taddei, PG De Benedetti, S Cotecchia FEBS letters 399 (1-2), 9-13, 1996 | 93 | 1996 |
| Development of Quantitative Structure−Property Relationships Using Calculated Descriptors for the Prediction of the Physicochemical Properties (nD, ρ, bp, ε, η) of … M Cocchi, PG De Benedetti, R Seeber, L Tassi, A Ulrici Journal of chemical information and computer sciences 39 (6), 1190-1203, 1999 | 71 | 1999 |
| Synthesis, Screening, and Molecular Modeling of New Potent and Selective Antagonists at the α1d Adrenergic Receptor A Leonardi, D Barlocco, F Montesano, G Cignarella, G Motta, R Testa, ... Journal of medicinal chemistry 47 (8), 1900-1918, 2004 | 67 | 2004 |
| The binding of benzenesulfonamides to carbonic anhydrase enzyme. A molecular mechanics study and quantitative structure-activity relationships MC Menziani, PG De Benedetti, F Gago, WG Richards Journal of medicinal chemistry 32 (5), 951-956, 1989 | 64 | 1989 |
| Mapping the Peripheral Benzodiazepine Receptor Binding Site by Conformationally Restrained Derivatives of 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3 … A Cappelli, M Anzini, S Vomero, PG De Benedetti, MC Menziani, G Giorgi, ... Journal of medicinal chemistry 40 (18), 2910-2921, 1997 | 63 | 1997 |
| Computational quantum chemistry and adaptive ligand modeling in mechanistic QSAR PG De Benedetti, F Fanelli Drug discovery today 15 (19-20), 859-866, 2010 | 50 | 2010 |
| Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 2. Molecular Basis of the Intrinsic Efficacy of Arylpiperazine Derivatives at … A Cappelli, M Anzini, S Vomero, L Canullo, L Mennuni, F Makovec, ... Journal of medicinal chemistry 42 (9), 1556-1575, 1999 | 48 | 1999 |
| Ab InitioModeling and Molecular Dynamics Simulation of the α1b-Adrenergic Receptor Activation F Fanelli, C Menziani, A Scheer, S Cotecchia, PG De Benedetti Methods 14 (3), 302-317, 1998 | 46 | 1998 |
| Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino) ethyl]-1, 4-benzodiazepines as novel tifluadom-like ligands with high affinity … A Cappelli, M Anzini, S Vomero, MC Menziani, PG De Benedetti, ... Journal of medicinal chemistry 39 (4), 860-872, 1996 | 46 | 1996 |
