Robert A Grassucci
Robert A Grassucci
Research Specialist Columbia/HHMI
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Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation
RK Agrawal, P Penczek, RA Grassucci, J Frank
Proceedings of the National Academy of Sciences 95 (11), 6134-6138, 1998
Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit
CMT Spahn, JS Kieft, RA Grassucci, PA Penczek, K Zhou, JA Doudna, ...
Science 291 (5510), 1959-1962, 2001
Solution structure of the E. coli 70S ribosome at 11.5 Å resolution
IS Gabashvili, RK Agrawal, CMT Spahn, RA Grassucci, DI Svergun, ...
Cell 100 (5), 537-549, 2000
A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome
J Frank, J Zhu, P Penczek, Y Li, S Srivastava, A Verschoor, ...
Nature 376 (6539), 441-444, 1995
The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles
PA Penczek, RA Grassucci, J Frank
Ultramicroscopy 53 (3), 251-270, 1994
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
M Halic, T Becker, MR Pool, CMT Spahn, RA Grassucci, J Frank, ...
Nature 427 (6977), 808-814, 2004
Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex
R Beckmann, D Bubeck, R Grassucci, P Penczek, A Verschoor, G Blobel, ...
Science 278 (5346), 2123-2126, 1997
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation
CMT Spahn, MG Gomez‐Lorenzo, RA Grassucci, R Jørgensen, ...
The EMBO journal 23 (5), 1008-1019, 2004
EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome
RK Agrawal, AB Heagle, P Penczek, RA Grassucci, J Frank
Nature structural biology 6 (7), 643-647, 1999
Cryo‐EM reveals an active role for aminoacyl‐tRNA in the accommodation process
M Valle, J Sengupta, NK Swami, RA Grassucci, N Burkhardt, KH Nierhaus, ...
The EMBO journal 21 (13), 3557-3567, 2002
A 9 Å resolution X-ray crystallographic map of the large ribosomal subunit
N Ban, B Freeborn, P Nissen, P Penczek, RA Grassucci, R Sweet, J Frank, ...
Cell 93 (7), 1105-1115, 1998
Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum
T Wagenknecht, R Grassucci, J Frank, A Saito, M Inui, S Fleischer
Nature 338 (6211), 167-170, 1989
Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle.
M Radermacher, V Rao, R Grassucci, J Frank, AP Timerman, S Fleischer, ...
The Journal of cell biology 127 (2), 411-423, 1994
Structure of a mammalian ryanodine receptor
R Zalk, OB Clarke, A Des Georges, RA Grassucci, S Reiken, F Mancia, ...
Nature 517 (7532), 44-49, 2015
Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor
CMT Spahn, E Jan, A Mulder, RA Grassucci, P Sarnow, J Frank
Cell 118 (4), 465-475, 2004
Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
E Villa, J Sengupta, LG Trabuco, J LeBarron, WT Baxter, TR Shaikh, ...
Proceedings of the National Academy of Sciences 106 (4), 1063-1068, 2009
Direct visualization of A-, P-, and E-site transfer RNAs in the Escherichia coli ribosome
RK Agrawal, P Penczek, RA Grassucci, Y Li, AD Leith, KH Nierhaus, ...
Science 271 (5251), 1000-1002, 1996
The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22
IS Gabashvili, ST Gregory, M Valle, R Grassucci, M Worbs, MC Wahl, ...
Molecular cell 8 (1), 181-188, 2001
Escherichia coli 70 S ribosome at 15 Å resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein
A Malhotra, P Penczek, RK Agrawal, IS Gabashvili, RA Grassucci, ...
Journal of molecular biology 280 (1), 103-116, 1998
Visualization of Trna Movements on the Escherichia coli 70s Ribosome during the Elongation Cycle
RK Agrawal, CMT Spahn, P Penczek, RA Grassucci, KH Nierhaus, ...
The Journal of Cell Biology 150 (3), 447-460, 2000
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