Editing DNA methylation in the mammalian genome XS Liu, H Wu, X Ji, Y Stelzer, X Wu, S Czauderna, J Shu, D Dadon, ... Cell 167 (1), 233-247. e17, 2016 | 1233 | 2016 |
Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ... Cell 172 (5), 979-992. e6, 2018 | 443 | 2018 |
PDZ domains of Par-3 as potential phosphoinositide signaling integrators H Wu, W Feng, J Chen, LN Chan, S Huang, M Zhang Molecular cell 28 (5), 886-898, 2007 | 223 | 2007 |
Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease H Wu, J Luo, H Yu, A Rattner, A Mo, Y Wang, PM Smallwood, B Erlanger, ... Neuron 81 (1), 103-119, 2014 | 213 | 2014 |
Molecular basis of Bcl-xL’s target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1 W Feng, S Huang, H Wu, M Zhang Journal of molecular biology 372 (1), 223-235, 2007 | 205 | 2007 |
Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment W Feng, H Wu, LN Chan, M Zhang Journal of biological chemistry 283 (34), 23440-23449, 2008 | 156 | 2008 |
Complete morphologies of basal forebrain cholinergic neurons in the mouse H Wu, J Williams, J Nathans elife 3, e02444, 2014 | 155 | 2014 |
Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor R Wang, Z Wei, H Jin, H Wu, C Yu, W Wen, LN Chan, Z Wen, M Zhang Molecular cell 33 (6), 692-703, 2009 | 114 | 2009 |
Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice X Tang, J Drotar, K Li, CD Clairmont, AS Brumm, AJ Sullins, H Wu, XS Liu, ... Science translational medicine 11 (503), eaau0164, 2019 | 102 | 2019 |
Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes L Pan, H Wu, C Shen, Y Shi, W Jin, J Xia, M Zhang The EMBO journal 26 (21), 4576-4587, 2007 | 87 | 2007 |
The Par‐3 NTD adopts a PB1‐like structure required for Par‐3 oligomerization and membrane localization W Feng, H Wu, LN Chan, M Zhang The EMBO journal 26 (11), 2786-2796, 2007 | 82 | 2007 |
Hypoxia‐inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E–deficient mice A Maier, H Wu, N Cordasic, P Oefner, B Dietel, C Thiele, A Weidemann, ... The FASEB Journal 31 (11), 4971-4984, 2017 | 66 | 2017 |
Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling H Wu, J Williams, J Nathans Elife 1, e00181, 2012 | 63 | 2012 |
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein W Wen, L Chen, H Wu, X Sun, M Zhang, DK Banfield Molecular biology of the cell 17 (10), 4282-4299, 2006 | 52 | 2006 |
Parent-of-origin DNA methylation dynamics during mouse development Y Stelzer, H Wu, Y Song, CS Shivalila, S Markoulaki, R Jaenisch Cell reports 16 (12), 3167-3180, 2016 | 38 | 2016 |
Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons JD Graef, H Wu, C Ng, C Sun, V Villegas, D Qadir, K Jesseman, ... European Journal of Neuroscience 51 (10), 2143-2157, 2020 | 33 | 2020 |
Flat mount imaging of mouse skin and its application to the analysis of hair follicle patterning and sensory axon morphology H Chang, Y Wang, H Wu, J Nathans JoVE (Journal of Visualized Experiments), e51749, 2014 | 20 | 2014 |
Methods of editing DNA methylation R Jaenisch, XS Liu, H Wu US Patent 11,434,476, 2022 | 6 | 2022 |
Collagenases are critical for skeletal and soft connective tissue remodeling: abnormalities in mice that express, in the germline, an engineered mutation in the Col1a1 gene … H Wu, X Liu, M Byrne, Y Harada, S Krane, R Jaenisch J Bone Miner Res 9, S141-S141, 1994 | 5 | 1994 |
An in vivo assessment ofthe contribution of type I collagen to the mechanical properties of cortical bone K Jepsen, M Mansoura, J Kuhn, H Wu, R Jaenisch, J Bonadio, ... 38th Annual Meeting, Orthopaedic Research Society, 1992 | 5 | 1992 |