Ramona Curpan
Ramona Curpan
Researcher, Coriolan Dragulescu Institute of Chemistry
Verifierad e-postadress på acad-icht.tm.edu.ro
Citeras av
Citeras av
WOMBAT: world of molecular bioactivity
M Olah, M Mracec, L Ostopovici, R Rad, A Bora, N Hadaruga, I Olah, ...
Chemoinformatics in drug discovery 223239, 2004
DrugCentral 2021 supports drug discovery and repositioning
S Avram, CG Bologa, J Holmes, G Bocci, TB Wilson, DT Nguyen, ...
Nucleic acids research 49 (D1), D1160-D1169, 2021
A crowdsourcing evaluation of the NIH chemical probes
TI Oprea, CG Bologa, S Boyer, RF Curpan, RC Glen, AL Hopkins, ...
Nature chemical biology 5 (7), 441-447, 2009
Lead-like, drug-like or “Pub-like”: how different are they?
TI Oprea, TK Allu, DC Fara, RF Rad, L Ostopovici, CG Bologa
Journal of Computer-Aided Molecular Design 21, 113-119, 2007
The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1
JS Lewis-Wambi, H Kim, R Curpan, R Grigg, MA Sarker, VC Jordan
Molecular pharmacology 80 (4), 610-620, 2011
ChemProt: a disease chemical biology database
O Taboureau, SK Nielsen, K Audouze, N Weinhold, D Edsgärd, FS Roque, ...
Nucleic acids research 39 (suppl_1), D367-D372, 2010
WOMBAT and WOMBAT‐PK: bioactivity databases for lead and drug discovery
M Olah, R Rad, L Ostopovici, A Bora, N Hadaruga, D Hadaruga, ...
Chemical biology: from small molecules to systems biology and drug design 1 …, 2007
Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells
S Sengupta, I Obiorah, PY Maximov, R Curpan, VC Jordan
British journal of pharmacology 169 (1), 167-178, 2013
Structure− function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen
PY Maximov, CB Myers, RF Curpan, JS Lewis-Wambi, VC Jordan
Journal of medicinal chemistry 53 (8), 3273-3283, 2010
Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs
R Burai, C Ramesh, M Shorty, R Curpan, C Bologa, LA Sklar, T Oprea, ...
Organic & biomolecular chemistry 8 (9), 2252-2259, 2010
Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators
VC Jordan, R Curpan, PY Maximov
Journal of the National Cancer Institute 107 (6), djv075, 2015
Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt® high-throughput flow cytometry system
MK Haynes, JJ Strouse, A Waller, A Leitao, RF Curpan, C Bologa, ...
SLAS Discovery 14 (6), 596-609, 2009
The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy
P Fan, PY Maximov, RF Curpan, B Abderrahman, VC Jordan
Molecular and cellular endocrinology 418, 245-263, 2015
Endoxifen, 4-hydroxytamoxifen and an estrogenic derivative modulate estrogen receptor complex mediated apoptosis in breast cancer
PY Maximov, B Abderrahman, SW Fanning, S Sengupta, P Fan, ...
Molecular pharmacology 94 (2), 812-822, 2018
Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer
I Obiorah, S Sengupta, R Curpan, VC Jordan
Molecular pharmacology 85 (5), 789-799, 2014
Structural determinants of the alpha2 adrenoceptor subtype selectivity
L Ostopovici-Halip, R Curpăn, M Mracec, CG Bologa
Journal of Molecular Graphics and Modelling 29 (8), 1030-1038, 2011
Origin of uterine fibroids: conversion of myometrial stem cells to tumor-initiating cells
H Elkafas, Y Qiwei, A Al-Hendy
Seminars in reproductive medicine 35 (06), 481-486, 2017
High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry
RF Curpan, PC Simons, D Zhai, SM Young, MB Carter, CG Bologa, ...
Assay and drug development technologies 9 (5), 465-474, 2011
Pharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients
PY Maximov, RE McDaniel, DJ Fernandes, P Bhatta, VR Korostyshevskiy, ...
Journal of the National Cancer Institute 106 (10), dju283, 2014
A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers
PY Maximov, B Abderrahman, RF Curpan, YM Hawsawi, P Fan, ...
Endocrine-related cancer 25 (2), R83-R113, 2018
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