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Jim Mulloy
Jim Mulloy
Adjunct Professor of Pediatrics, CCHMC
Verified email at cchmc.org
Title
Cited by
Cited by
Year
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ...
Nature 478 (7370), 524-528, 2011
20952011
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling
R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ...
Cell 172 (1), 90-105. e23, 2018
8572018
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification
H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ...
Cell stem cell 22 (2), 191-205. e9, 2018
8222018
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I
TS Migone, JX Lin, A Cereseto, JC Mulloy, JJ O'Shea, G Franchini, ...
Science 269 (5220), 79-81, 1995
6611995
Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia
Y Huang, R Su, Y Sheng, L Dong, Z Dong, H Xu, T Ni, ZS Zhang, T Zhang, ...
Cancer cell 35 (4), 677-691. e10, 2019
5862019
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer cell 38 (1), 79-96. e11, 2020
4452020
AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3
M Wunderlich, FS Chou, KA Link, B Mizukawa, RL Perry, M Carroll, ...
Leukemia 24 (10), 1785-1788, 2010
4442010
Rac1 GTPase: a “Rac” of all trades
EE Bosco, JC Mulloy, Y Zheng
Cellular and molecular life sciences 66, 370-374, 2009
4052009
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia
J Wei, M Wunderlich, C Fox, S Alvarez, JC Cigudosa, JS Wilhelm, ...
Cancer cell 13 (6), 483-495, 2008
3832008
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins
S Takemoto, JC Mulloy, A Cereseto, TS Migone, BKR Patel, M Matsuoka, ...
Proceedings of the National Academy of Sciences 94 (25), 13897-13902, 1997
3521997
The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells
JC Mulloy, J Cammenga, KL MacKenzie, FJ Berguido, MAS Moore, ...
Blood, The Journal of the American Society of Hematology 99 (1), 15-23, 2002
2762002
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ...
The Journal of clinical investigation 123 (10), 4144-4157, 2013
2592013
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia
S Mi, Z Li, P Chen, C He, D Cao, A Elkahloun, J Lu, LA Pelloso, ...
Proceedings of the National Academy of Sciences 107 (8), 3710-3715, 2010
249*2010
TET1 plays an essential oncogenic role in MLL-rearranged leukemia
H Huang, X Jiang, Z Li, Y Li, CX Song, C He, M Sun, P Chen, S Gurbuxani, ...
Proceedings of the National Academy of Sciences 110 (29), 11994-11999, 2013
2312013
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
S Goyama, J Schibler, L Cunningham, Y Zhang, Y Rao, N Nishimoto, ...
The Journal of clinical investigation 123 (9), 3876-3888, 2013
2202013
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome
GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ...
Cancer cell 24 (1), 90-104, 2013
2102013
Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain
JC Mulloy, T Kislyakova, A Cereseto, L Casareto, A LoMonico, J Fullen, ...
Journal of virology 72 (11), 8852-8860, 1998
2071998
Rho GTPases in hematopoiesis and hemopathies
JC Mulloy, JA Cancelas, MD Filippi, TA Kalfa, F Guo, Y Zheng
Blood, The Journal of the American Society of Hematology 115 (5), 936-947, 2010
1852010
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia
Z Li, H Huang, P Chen, M He, Y Li, S Arnovitz, X Jiang, C He, E Hyjek, ...
Nature communications 3 (1), 1-12, 2012
1832012
p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells
A Cereseto, F Diella, JC Mulloy, A Cara, P Michieli, R Grassmann, ...
1701996
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