| MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A AG Rocha, A Franco, AM Krezel, JM Rumsey, JM Alberti, WC Knight, ... Science 360 (6386), 336-341, 2018 | 231 | 2018 |
| The Discovery of a Highly Selective 5,6,7,8‐Tetrahydrobenzo[4,5]thieno[2,3‐d]pyrimidin‐4(3H)‐one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson … P Di Fruscia, E Zacharioudakis, C Liu, S Moniot, S Laohasinnarong, ... ChemMedChem 10 (1), 69-82, 2015 | 79 | 2015 |
| Inhibitors of BRAF dimers using an allosteric site XM Cotto-Rios, B Agianian, N Gitego, E Zacharioudakis, O Giricz, Y Wu, ... Nature communications 11 (1), 4370, 2020 | 61 | 2020 |
| Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 622 (7983), 627-636, 2023 | 59 | 2023 |
| Modulating mitofusins to control mitochondrial function and signaling E Zacharioudakis, B Agianian, V Kumar MV, N Biris, TP Garner, ... Nature communications 13 (1), 3775, 2022 | 38 | 2022 |
| Eltrombopag directly inhibits BAX and prevents cell death AZ Spitz, E Zacharioudakis, DE Reyna, TP Garner, E Gavathiotis Nature communications 12 (1), 1134, 2021 | 30 | 2021 |
| Chromatin regulates genome targeting with cisplatin E Zacharioudakis, P Agarwal, A Bartoli, N Abell, L Kunalingam, ... Angewandte Chemie 129 (23), 6583-6587, 2017 | 30 | 2017 |
| Mitochondrial dynamics proteins as emerging drug targets E Zacharioudakis, E Gavathiotis Trends in pharmacological sciences 44 (2), 112-127, 2023 | 28 | 2023 |
| Quinolizinium as a new fluorescent lysosomotropic probe E Zacharioudakis, T Cañeque, R Custodio, S Müller, AM Cuadro, ... Bioorganic & Medicinal Chemistry Letters 27 (2), 203-207, 2017 | 24 | 2017 |
| BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells V Azzoni, J Wicinski, M Macario, M Castagné, P Finetti, K Ambrosova, ... Cell Death & Disease 13 (2), 96, 2022 | 15 | 2022 |
| Iron-dependent lysosomal dysfunction mediated by a natural product hybrid RR A Mariani, TT Mai, E Zacharioudakis, A Heinzsch, A Bartoli, T Caneque CHEMICAL COMMUNICATIONS, 1358-1360, 2016 | 11 | 2016 |
| Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia C Glytsou, X Chen, E Zacharioudakis, W Al-Santli, H Zhou, B Nadorp, ... Cancer discovery 13 (7), 1656-1677, 2023 | 6 | 2023 |
| Direct small molecule activation of mitofusins E Zacharioudakis, N Biris, TP Garner, Y Chen, R Pekson, R Dhingra, ... BioRxiv, 301713, 2018 | 6 | 2018 |
| Targeting protein conformations with small molecules to control protein complexes E Zacharioudakis, E Gavathiotis Trends in biochemical sciences 47 (12), 1023-1037, 2022 | 4 | 2022 |
| Apoptotic stress causes mtDNA release during senescence and drives the SASP (vol 622, pg 627, 2023) S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 625 (7995), E15-E15, 2024 | 1 | 2024 |
| Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature, 1-1, 2024 | | 2024 |
| Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model GK Carling, L Fan, NR Foxe, K Norman, P Ye, MY Wong, D Zhu, F Yu, ... bioRxiv, 2024.01. 24.577107, 2024 | | 2024 |
| Mitofusin activators and uses thereof E Gavathiotis, RN Kitsis, N Biris, E Zacharioudakis US Patent 11,813,268, 2023 | | 2023 |
| Repurposing Platinum (IV) Prodrugs to Modulate Mitochondrial Metabolism E Zacharioudakis, R Rodriguez ACS Central Science 9 (7), 1257-1259, 2023 | | 2023 |
| Modulating Copper Reactivity: A New Approach to Reprogram Mitochondrial Retrograde Signaling E Zacharioudakis ACS Chemical Biology 18 (6), 1256-1258, 2023 | | 2023 |
