Biswaranjan Pani
Biswaranjan Pani
Duke University Medical Center
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Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx Evidence for similarities in store-operated and calcium release-activated …
HL Ong, KT Cheng, X Liu, BC Bandyopadhyay, BC Paria, J Soboloff, ...
Journal of Biological Chemistry 282 (12), 9105-9116, 2007
GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling
ARB Thomsen, B Plouffe, TJ Cahill III, AK Shukla, JT Tarrasch, AM Dosey, ...
Cell 166 (4), 907-919, 2016
Lipid rafts/caveolae as microdomains of calcium signaling
B Pani, BB Singh
Cell calcium 45 (6), 625-633, 2009
Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1 (−/−) mice
X Liu, KT Cheng, BC Bandyopadhyay, B Pani, A Dietrich, BC Paria, ...
Proceedings of the National Academy of Sciences 104 (44), 17542-17547, 2007
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE)
B Pani, HL Ong, X Liu, K Rauser, IS Ambudkar, BB Singh
Journal of Biological Chemistry 283 (25), 17333-17340, 2008
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1
B Pani, HL Ong, WB So-ching, X Liu, K Rauser, BB Singh, IS Ambudkar
Proceedings of the National Academy of Sciences 106 (47), 20087-20092, 2009
Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9
LM Luttrell, J Wang, B Plouffe, JS Smith, L Yamani, S Kaur, ...
Sci. Signal. 11 (549), eaat7650, 2018
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
X Liu, S Ahn, AW Kahsai, KC Meng, NR Latorraca, B Pani, ...
Nature 548 (7668), 480-484, 2017
Up-Regulation of Transient Receptor Potential Canonical 1 (TRPC1) following Sarco(endo)plasmic Reticulum Ca2+ ATPase 2 Gene Silencing Promotes Cell …
B Pani, E Cornatzer, W Cornatzer, DM Shin, MR Pittelkow, A Hovnanian, ...
Molecular biology of the cell 17 (10), 4446-4458, 2006
Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library
S Ahn, AW Kahsai, B Pani, QT Wang, S Zhao, AL Wall, RT Strachan, ...
Proceedings of the National Academy of Sciences 114 (7), 1708-1713, 2017
Impairment of TRPC1–STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1
B Pani, X Liu, S Bollimuntha, KT Cheng, IR Niesman, C Zheng, VR Achen, ...
Journal of cell science 126 (2), 667-675, 2013
Conformationally selective RNA aptamers allosterically modulate the β 2-Adrenoceptor
AW Kahsai, JW Wisler, J Lee, S Ahn, TJ Cahill III, SM Dennison, DP Staus, ...
Nature chemical biology 12 (9), 709-716, 2016
The TR (i) P to Ca2+ signaling just got STIMy: an update on STIM1 activated TRPC channels
B Pani, S Bollimuntha, BB Singh
Frontiers in bioscience: a journal and virtual library 17, 805, 2012
Darier’s disease: a calcium-signaling perspective
B Pani, BB Singh
Cellular and Molecular Life Sciences 65 (2), 205-211, 2008
Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling
DP Staus, LM Wingler, M Choi, B Pani, A Manglik, AC Kruse, RJ Lefkowitz
Proceedings of the National Academy of Sciences 115 (15), 3834-3839, 2018
G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor
M Choi, DP Staus, LM Wingler, S Ahn, B Pani, WD Capel, RJ Lefkowitz
Science signaling 11 (544), 2018
Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity
A Chauhan, Y Sun, B Pani, F Quenumzangbe, J Sharma, BB Singh, ...
PLoS One 9 (7), e101023, 2014
Small-molecule positive allosteric modulators of the β2-adrenoceptor isolated from DNA-encoded libraries
S Ahn, B Pani, AW Kahsai, EK Olsen, G Husemoen, M Vestergaard, L Jin, ...
Molecular Pharmacology 94 (2), 850-861, 2018
Mechanism of β2AR regulation by an intracellular positive allosteric modulator
X Liu, A Masoudi, AW Kahsai, LY Huang, B Pani, DP Staus, PJ Shim, ...
Science 364 (6447), 1283-1287, 2019
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