Följ
Benjamin R. Sabari
Benjamin R. Sabari
Assistant Professor, UT Southwestern Medical Center
Verifierad e-postadress på utsouthwestern.edu
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Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
18482018
Transcription factors activate genes through the phase-separation capacity of their activation domains
A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ...
Cell 175 (7), 1842-1855. e16, 2018
13202018
Metabolic regulation of gene expression through histone acylations
BR Sabari, D Zhang, CD Allis, Y Zhao
Nature reviews Molecular cell biology 18 (2), 90-101, 2017
8052017
Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation
BR Sabari, Z Tang, H Huang, V Yong-Gonzalez, H Molina, HE Kong, ...
Molecular cell 58 (2), 203-215, 2015
4992015
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
YE Guo, JC Manteiga, JE Henninger, BR Sabari, A Dall’Agnese, ...
Nature 572 (7770), 543-548, 2019
4932019
SnapShot: histone modifications
H Huang, BR Sabari, BA Garcia, CD Allis, Y Zhao
Cell 159 (2), 458-458. e1, 2014
4382014
Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark
L Dai, C Peng, E Montellier, Z Lu, Y Chen, H Ishii, A Debernardi, ...
Nature chemical biology 10 (5), 365-370, 2014
3982014
Molecular coupling of histone crotonylation and active transcription by AF9 YEATS domain
Y Li, BR Sabari, T Panchenko, H Wen, D Zhao, H Guan, L Wan, H Huang, ...
Molecular cell 62 (2), 181-193, 2016
3172016
Enhancer features that drive formation of transcriptional condensates
K Shrinivas, BR Sabari, EL Coffey, IA Klein, A Boija, AV Zamudio, ...
Molecular cell 75 (3), 549-561. e7, 2019
3062019
Partitioning of cancer therapeutics in nuclear condensates
IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ...
Science 368 (6497), 1386-1392, 2020
3032020
Biomolecular condensates in the nucleus
BR Sabari, A Dall’Agnese, RA Young
Trends in biochemical sciences 45 (11), 961-977, 2020
2842020
Mediator condensates localize signaling factors to key cell identity genes
AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ...
Molecular cell 76 (5), 753-766. e6, 2019
2002019
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas
J Bayliss, P Mukherjee, C Lu, SU Jain, C Chung, D Martinez, B Sabari, ...
Science translational medicine 8 (366), 366ra161-366ra161, 2016
1712016
Functional partitioning of transcriptional regulators by patterned charge blocks
H Lyons, RT Veettil, P Pradhan, C Fornero, N De La Cruz, K Ito, M Eppert, ...
Cell 186 (2), 327-345. e28, 2023
812023
Biomolecular condensates and gene activation in development and disease
BR Sabari
Developmental cell 55 (1), 84-96, 2020
482020
Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells
FR Melo, O Wallerman, A Paivandy, G Calounova, AM Gustafson, ...
Journal of Allergy and Clinical Immunology 140 (2), 474-485, 2017
472017
Is transcriptional regulation just going through a phase?
GJ Narlikar, S Myong, D Larson, K Maeshima, N Francis, K Rippe, ...
Molecular cell 81 (8), 1579-1585, 2021
322021
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ...
Science translational medicine 13 (614), eabc0497, 2021
282021
Phase separation in biology and disease; current perspectives and open questions
S Boeynaems, S Chong, J Gsponer, L Holt, D Milovanovic, DM Mitrea, ...
Journal of molecular biology 435 (5), 167971, 2023
132023
Charles David Allis (1951–2023)
P Chi, PW Lewis, C Lu, J Lu, AJ Ruthenburg, BR Sabari, D Shechter, ...
Nature genetics 55 (4), 522-523, 2023
12023
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Artiklar 1–20