| Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion SE Golding, E Rosenberg, N Valerie, I Hussaini, M Frigerio, XF Cockcroft, ... Molecular cancer therapeutics, 1535-7163. MCT-09-0519, 2009 | 274 | 2009 |
| ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation L Biddlestone-Thorpe, M Sajjad, E Rosenberg, JM Beckta, NCK Valerie, ... Clinical Cancer Research 19 (12), 3189-3200, 2013 | 145 | 2013 |
| Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2 M Carter, AS Jemth, A Hagenkort, BDG Page, R Gustafsson, JJ Griese, ... Nature communications 6 (1), 1-10, 2015 | 75 | 2015 |
| Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells NCK Valerie, B Dziegielewska, AS Hosing, E Augustin, LS Gray, ... Biochemical pharmacology 85 (7), 888-897, 2013 | 63 | 2013 |
| Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies N Herold, SG Rudd, L Ljungblad, K Sanjiv, IH Myrberg, CBJ Paulin, ... Nature medicine 23 (2), 256-263, 2017 | 61 | 2017 |
| NUDT15 hydrolyzes 6-thio-deoxyGTP to mediate the anticancer efficacy of 6-thioguanine NCK Valerie, A Hagenkort, BDG Page, G Masuyer, D Rehling, M Carter, ... Cancer research 76 (18), 5501-5511, 2016 | 49 | 2016 |
| Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation NCK Valerie, EV Casarez, JO DaSilva, ME Dunlap-Brown, SJ Parsons, ... Cancer research 71 (21), 6817-6826, 2011 | 48 | 2011 |
| Mutations in the BRCT binding site of BRCA1 result in hyper-recombination SM Dever, SE Golding, E Rosenberg, BR Adams, MO Idowu, JM Quillin, ... Aging (Albany NY) 3 (5), 515, 2011 | 41 | 2011 |
| Pathways controlling dNTP pools to maintain genome stability SG Rudd, NCK Valerie, T Helleday DNA Repair 44, 193-204, 2016 | 38 | 2016 |
| PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinase AS Hosing, NCK Valerie, J Dziegielewski, DL Brautigan, JM Larner Journal of Biological Chemistry 287 (12), 9230-9239, 2012 | 32 | 2012 |
| Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1 S Llona-Minguez, A Hoglund, SA Jacques, L Johansson, ... Journal of medicinal chemistry 59 (3), 1140-1148, 2016 | 26 | 2016 |
| Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells BDG Page, NCK Valerie, RHG Wright, O Wallner, R Isaksson, M Carter, ... Nature communications 9 (1), 1-14, 2018 | 19 | 2018 |
| Orally bioavailable and blood–brain barrier-penetrating ATM inhibitor (AZ32) radiosensitizes intracranial gliomas in mice J Karlin, J Allen, SF Ahmad, G Hughes, V Sheridan, R Odedra, ... Molecular cancer therapeutics 17 (8), 1637-1647, 2018 | 15 | 2018 |
| Piperazin-1-ylpyridazine derivatives are a novel class of human dCTP pyrophosphatase 1 inhibitors S Llona-Minguez, A Hoglund, A Ghassemian, M Desroses, ... Journal of medicinal chemistry 60 (10), 4279-4292, 2017 | 11 | 2017 |
| Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells BDG Page, NCK Valerie, RHG Wright, O Wallner, R Isaksson, M Carter, ... Nature communications 10 (1), 1-1, 2019 | 1 | 2019 |
| Abstract LB-262: Targeting T-type calcium channels induces the extrinsic apoptotic pathway and sensitizes glioblastoma cancer cells to radio-and chemotherapy J Dziegielewski, NCK Valerie, B Dziegielewska, AS Hosing, LS Gray, ... Cancer Research 72 (8 Supplement), LB-262-LB-262, 2012 | 1 | 2012 |
| Development of a chemical probe against NUDT15 SM Zhang, M Desroses, A Hagenkort, NCK Valerie, D Rehling, M Carter, ... Nature Chemical Biology, 1-9, 2020 | | 2020 |
| NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE B Page, NCK Valerie, T Helleday, O Wallner, M Scobie, S Llona-Minguez WO Patent App. WO2019020828A9, 2019 | | 2019 |
| Roles of NUDT5 and NUDT15 beyond oxidized nucleotide sanitation and their potential as therapeutic targets NCK Valerie Inst för medicinsk biokemi och biofysik/Dept of Medical Biochemistry and …, 2018 | | 2018 |
| Abstract A239: T-type calcium channels as a novel molecular target for tumor therapy. B Dziegielewska, NCK Valerie, AS Hosing, JM Larner, DL Brautigan, ... Molecular Cancer Therapeutics 12 (11 Supplement), A239-A239, 2013 | | 2013 |
Kristoffer ValerieVerified email at vcu.edu
