Asparagine bioavailability governs metastasis in a model of breast cancer SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ... Nature 554 (7692), 378-381, 2018 | 451 | 2018 |
A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis E Wagenblast, M Soto, S Gutiérrez-Ángel, CA Hartl, AL Gable, AR Maceli, ... Nature 520 (7547), 358-362, 2015 | 424 | 2015 |
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis JJ Ipsaro, AD Haase, SR Knott, L Joshua-Tor, GJ Hannon Nature 491 (7423), 279-283, 2012 | 357 | 2012 |
Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans CWY Ha, A Martin, GD Sepich-Poore, B Shi, Y Wang, K Gouin, ... Cell 183 (3), 666-683. e17, 2020 | 249 | 2020 |
Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae SRV Knott, JM Peace, AZ Ostrow, Y Gan, AE Rex, CJ Viggiani, S Tavaré, ... Cell 148 (1), 99-111, 2012 | 231 | 2012 |
Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in … SRV Knott, CJ Viggiani, S Tavaré, OM Aparicio Genes & development 23 (9), 1077-1090, 2009 | 171 | 2009 |
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth AS Krall, PJ Mullen, F Surjono, M Momcilovic, EW Schmid, CJ Halbrook, ... Cell metabolism 33 (5), 1013-1026. e6, 2021 | 157 | 2021 |
The level of origin firing inversely affects the rate of replication fork progression Y Zhong, T Nellimoottil, JM Peace, SRV Knott, SK Villwock, JM Yee, ... Journal of Cell Biology 201 (3), 373-383, 2013 | 124 | 2013 |
A computational algorithm to predict shRNA potency SRV Knott, AR Maceli, N Erard, K Chang, K Marran, X Zhou, A Gordon, ... Molecular cell 56 (6), 796-807, 2014 | 117 | 2014 |
Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae SJ Szyjka, JG Aparicio, CJ Viggiani, S Knott, W Xu, S Tavaré, OM Aparicio Genes & development 22 (14), 1906-1920, 2008 | 109 | 2008 |
Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases JG Reiter, WT Hung, IH Lee, S Nagpal, P Giunta, S Degner, G Liu, ... Nature genetics 52 (7), 692-700, 2020 | 90 | 2020 |
Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors EJ Crosby, J Wei, XY Yang, G Lei, T Wang, CX Liu, P Agarwal, AJ Korman, ... Oncoimmunology 7 (5), e1421891, 2018 | 86 | 2018 |
An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer KH Gouin III, N Ing, JT Plummer, CJ Rosser, B Ben Cheikh, C Oh, ... Nature communications 12 (1), 4906, 2021 | 79 | 2021 |
Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains JE Dalton, JM Fear, S Knott, BS Baker, LM McIntyre, MN Arbeitman Bmc Genomics 14, 1-15, 2013 | 66 | 2013 |
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain J Dai, PJ Cimino, KH Gouin III, CA Grzelak, A Barrett, AR Lim, A Long, ... Nature cancer 3 (1), 25-42, 2022 | 64 | 2022 |
lncRNA requirements for mouse acute myeloid leukemia and normal differentiation MJ Delas, LR Sabin, E Dolzhenko, SRV Knott, E Munera Maravilla, ... Elife 6, e25607, 2017 | 62 | 2017 |
Dynamic, mating-induced gene expression changes in female head and brain tissues of Drosophila melanogaster JE Dalton, TS Kacheria, SRV Knott, MS Lebo, A Nishitani, LE Sanders, ... Bmc Genomics 11, 1-13, 2010 | 59 | 2010 |
A CRISPR resource for individual, combinatorial, or multiplexed gene knockout N Erard, SRV Knott, GJ Hannon Molecular cell 67 (2), 348-354. e4, 2017 | 54 | 2017 |
Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics AZ Ostrow, T Nellimoottil, SRV Knott, CA Fox, S Tavare, OM Aparicio PLoS One 9 (2), e87647, 2014 | 54 | 2014 |
Genome-wide network analysis reveals the global properties of IFN-β immediate transcriptional effects in humans GH Fernald, S Knott, A Pachner, SJ Caillier, K Narayan, JR Oksenberg, ... The Journal of Immunology 178 (8), 5076-5085, 2007 | 53 | 2007 |