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Oliv Eidam
Oliv Eidam
CADD and Data Science expert
Verified email at cadd-consulting.com
Title
Cited by
Cited by
Year
Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors
RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ...
Journal of medicinal chemistry 53 (13), 4891-4905, 2010
2682010
Covalent docking of large libraries for the discovery of chemical probes
N London, RM Miller, S Krishnan, K Uchida, JJ Irwin, O Eidam, L Gibold, ...
Nature Chemical Biology 10 (12), 1066–1072, 2014
2572014
Structural basis of chaperone–subunit complex recognition by the type 1 pilus assembly platform FimD
M Nishiyama, R Horst, O Eidam, T Herrmann, O Ignatov, M Vetsch, ...
The EMBO journal 24 (12), 2075-2086, 2005
1412005
Anguinomycins and derivatives: total syntheses, modeling, and biological evaluation of the inhibition of nucleocytoplasmic transport
S Bonazzi, O Eidam, S Güttinger, JY Wach, I Zemp, U Kutay, ...
Journal of the American Chemical Society 132 (4), 1432-1442, 2010
1262010
Structural and functional insights into the assembly of type 1 pili from Escherichia coli
G Capitani, O Eidam, R Glockshuber, MG Grütter
Microbes and infection 8 (8), 2284-2290, 2006
982006
Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids as β-lactamase inhibitors
O Eidam, C Romagnoli, E Caselli, K Babaoglu, DT Pohlhaus, J Karpiak, ...
Journal of medicinal chemistry 53 (21), 7852-7863, 2010
912010
Fragment-guided design of subnanomolar β-lactamase inhibitors active in vivo
O Eidam, C Romagnoli, G Dalmasso, S Barelier, E Caselli, R Bonnet, ...
Proceedings of the National Academy of Sciences 109 (43), 17448-17453, 2012
842012
Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation
C Puorger, O Eidam, G Capitani, D Erilov, MG Grütter, R Glockshuber
Structure 16 (4), 631-642, 2008
842008
Increasing chemical space coverage by combining empirical and computational fragment screens
S Barelier, O Eidam, I Fish, J Hollander, F Figaroa, R Nachane, JJ Irwin, ...
ACS chemical biology 9 (7), 1528-1535, 2014
632014
Quality control of disulfide bond formation in pilus subunits by the chaperone FimC
MD Crespo, C Puorger, MA Schärer, O Eidam, MG Grütter, G Capitani, ...
Nature chemical biology 8 (8), 707-713, 2012
612012
Analysis of the productivity of DNA encoded libraries
O Eidam, AL Satz
MedChemComm 7 (7), 1323-1331, 2016
532016
Crystal structure of the ternary FimC–FimFt–FimDN complex indicates conserved pilus chaperone–subunit complex recognition by the usher FimD
O Eidam, FSN Dworkowski, R Glockshuber, MG Grütter, G Capitani
FEBS letters 582 (5), 651-655, 2008
512008
Homologous ligands accommodated by discrete conformations of a buried cavity
M Merski, M Fischer, TE Balius, O Eidam, BK Shoichet
Proceedings of the National Academy of Sciences 112 (16), 5039-5044, 2015
492015
Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells
F Roudnicky, JD Zhang, BK Kim, NJ Pandya, Y Lan, L Sach-Peltason, ...
Proceedings of the National Academy of Sciences 117 (33), 19854-19865, 2020
422020
Evidence for a novel domain of bacterial outer membrane ushers
G Capitani, O Eidam, MG Grütter
Proteins: Structure, Function, and Bioinformatics 65 (4), 816-823, 2006
262006
Development and Binding Mode Assessment of N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ …
A Tochowicz, S Dalziel, O Eidam, JD O’Connell III, S Griner, ...
Journal of medicinal chemistry 56 (13), 5446-5455, 2013
172013
Abstract LBA004: Identification of GSPT1-directed molecular glue degrader (MGD) for the treatment of Myc-driven breast cancer
G Gavory, B Fasching, D Bonenfant, A Sadok, A Singh, M Schillo, ...
Molecular Cancer Therapeutics 20 (12_Supplement), LBA004-LBA004, 2021
32021
Erratum: Covalent docking of large libraries for the discovery of chemical probes
N London, RM Miller, S Krishnan, K Uchida, JJ Irwin, O Eidam, L Gibold, ...
Nature Chemical Biology 11 (3), 235-235, 2015
22015
Isoindolinone compounds
A Flohr, O Eidam, B Fasching, M Meniconi, A Sadok, R Chopra, ...
US Patent App. 17/716,169, 2022
2022
ISOINDOLINONE COMPOUNDS
A FLOHR, O EIDAM, B FASCHING, M MENICONI, A SADOK, R CHOPRA, ...
WO Patent WO2,021,069,705, 2021
2021
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