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Teun P. de Boer
Teun P. de Boer
Associate Professor, Department of Medical Physiology, University Medical Center Utrecht
Verifierad e-postadress på umcutrecht.nl - Startsida
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TGF-β1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro
MJ Goumans, TP de Boer, AM Smits, LW van Laake, P van Vliet, ...
Stem cell research 1 (2), 138-149, 2008
2862008
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ...
Journal of molecular and cellular cardiology 96, 49-62, 2016
1622016
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
MKB Jonsson, MA Vos, GR Mirams, G Duker, P Sartipy, TP De Boer, ...
Journal of molecular and cellular cardiology 52 (5), 998-1008, 2012
1622012
The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on IK1
B Goversen, MAG van der Heyden, TAB van Veen, TP de Boer
Pharmacology & therapeutics 183, 127-136, 2018
1502018
The mammalian KIR2.x inward rectifier ion channel family: expression pattern and pathophysiology
TP De Boer, MJC Houtman, M Compier, MAG Van der Heyden
Acta physiologica 199 (3), 243-256, 2010
782010
High-throughput approaches for screening and analysis of cell behaviors
J Seo, JY Shin, J Leijten, O Jeon, G Camci-Unal, AD Dikina, K Brinegar, ...
Biomaterials 153, 85-101, 2018
742018
Comparison of the IKr blockers moxifloxacin, dofetilide and E‐4031 in five screening models of pro‐arrhythmia reveals lack of specificity of isolated cardiomyocytes
L Nalos, R Varkevisser, MKB Jonsson, MJC Houtman, JD Beekman, ...
British journal of pharmacology 165 (2), 467-478, 2012
742012
Sensing cardiac electrical activity with a cardiac myocyte–targeted optogenetic voltage indicator
ML Chang Liao, TP de Boer, H Mutoh, N Raad, C Richter, E Wagner, ...
Circulation research 117 (5), 401-412, 2015
732015
GNB5 mutations cause an autosomal-recessive multisystem syndrome with sinus bradycardia and cognitive disability
EM Lodder, P De Nittis, CD Koopman, W Wiszniewski, CFM de Souza, ...
The American Journal of Human Genetics 99 (3), 704-710, 2016
722016
Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics
KA Beattie, AP Hill, R Bardenet, Y Cui, JI Vandenberg, DJ Gavaghan, ...
Biophysical Journal 114 (3), 293a-294a, 2018
612018
Hyperpolarization induces differentiation in human cardiomyocyte progenitor cells
P van Vliet, TP de Boer, MAG van der Heyden, MK El Tamer, JPG Sluijter, ...
Stem cell reviews and reports 6, 178-185, 2010
602010
Perpetuation of torsade de pointes in heterogeneous hearts: competing foci or re‐entry?
N Vandersickel, TP de Boer, MA Vos, AV Panfilov
The Journal of physiology 594 (23), 6865-6878, 2016
562016
A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells.
JC Moore, R Spijker, AC Martens, T de Boer, MB Rook, ...
The International Journal of Developmental Biology 48 (1), 47-55, 2004
522004
Lysosome mediated Kir2. 1 breakdown directly influences inward rectifier current density
JA Jansen, TP de Boer, R Wolswinkel, TAB van Veen, MA Vos, ...
Biochemical and biophysical research communications 367 (3), 687-692, 2008
502008
A hybrid model for safety pharmacology on an automated patch clamp platform: Using dynamic clamp to join iPSC-derived cardiomyocytes and simulations of Ik1 ion channels in real …
B Goversen, TAB van Veen, N Fertig, TP de Boer
Frontiers in Physiology 8, 291010, 2018
492018
Optogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis
CJM van Opbergen, CD Koopman, BJM Kok, T Knöpfel, SL Renninger, ...
Theranostics 8 (17), 4750, 2018
482018
Connexin43 repression following epithelium-to-mesenchyme transition in embryonal carcinoma cells requires Snail1 transcription factor
TP De Boer, TAB Van Veen, MFA Bierhuizen, B Kok, MB Rook, ...
Differentiation 75 (3), 208-218, 2007
482007
The anti‐protozoal drug pentamidine blocks KIR2.x‐mediated inward rectifier current by entering the cytoplasmic pore region of the channel
TP De Boer, L Nalos, A Stary, B Kok, MJC Houtman, G Antoons, ...
British journal of pharmacology 159 (7), 1532-1541, 2010
472010
Myocardial tissue slices: organotypic pseudo-2D models for cardiac research & development
TP De Boer, P Camelliti, U Ravens, P Kohl
Future cardiology 5 (5), 425-430, 2009
462009
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments
CL Lei, M Clerx, DG Whittaker, DJ Gavaghan, TP de Boer, GR Mirams
Philosophical Transactions of the Royal Society A 378 (2173), 20190348, 2020
452020
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