| Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation A Abelein, A Gräslund, J Danielsson Proceedings of the National Academy of Sciences 112 (17), 5407-5412, 2015 | 118 | 2015 |
| Biophysical Studies of the Amyloid β‐Peptide: Interactions with Metal Ions and Small Molecules S Wärmländer, A Tiiman, A Abelein, J Luo, J Jarvet, KL Söderberg, ... ChemBioChem 14 (14), 1692-1704, 2013 | 98 | 2013 |
| The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway A Abelein, JP Abrahams, J Danielsson, A Gräslund, J Jarvet, J Luo, ... JBIC Journal of Biological Inorganic Chemistry 19, 623-634, 2014 | 88 | 2014 |
| Ionic Strength Modulation of the Free Energy Landscape of Aβ40 Peptide Fibril Formation A Abelein, J Jarvet, A Barth, A Graslund, J Danielsson Journal of the American Chemical Society 138 (21), 6893-6902, 2016 | 72 | 2016 |
| Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state G Chen, A Abelein, HE Nilsson, A Leppert, Y Andrade-Talavera, ... Nature Communications 8 (1), 2081, 2017 | 69 | 2017 |
| Characterization of Mn (II) ion binding to the amyloid-β peptide in Alzheimer⿿ s disease C Wallin, YS Kulkarni, A Abelein, J Jarvet, Q Liao, B Strodel, L Olsson, ... Journal of trace elements in medicine and biology 38, 183-193, 2016 | 58 | 2016 |
| Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid β self-assembly A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel Biochemistry 51 (1), 126-137, 2012 | 58 | 2012 |
| Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in Drosophila H Poska, M Haslbeck, FR Kurudenkandy, E Hermansson, G Chen, ... Biochemical Journal 473 (20), 3683-3704, 2016 | 47 | 2016 |
| Formation of dynamic soluble surfactant-induced amyloid β peptide aggregation intermediates A Abelein, JD Kaspersen, SB Nielsen, GV Jensen, G Christiansen, ... Journal of Biological Chemistry 288 (32), 23518-23528, 2013 | 45 | 2013 |
| High-yield production of amyloid-β peptide enabled by a customized spider silk domain A Abelein, G Chen, K Kitoka, R Aleksis, F Oleskovs, M Sarr, M Landreh, ... Scientific Reports 10 (1), 235, 2020 | 43 | 2020 |
| Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro G Chen, Y Andrade-Talavera, S Tambaro, A Leppert, HE Nilsson, ... Communications Biology 3 (1), 32, 2020 | 31 | 2020 |
| Transient small molecule interactions kinetically modulate amyloid β peptide self-assembly A Abelein, L Lang, C Lendel, A Gräslund, J Danielsson FEBS letters 586 (22), 3991-3995, 2012 | 30 | 2012 |
| Metal ion coordination delays amyloid-β peptide self-assembly by forming an aggregation–inert complex C Wallin, J Jarvet, H Biverstål, S Wärmländer, J Danielsson, A Gräslund, ... Journal of Biological Chemistry 295 (21), 7224-7234, 2020 | 21 | 2020 |
| High intracellular stability of the spidroin N‐terminal domain in spite of abundant amyloidogenic segments revealed by in‐cell hydrogen/deuterium exchange mass spectrometry M Kaldmäe, A Leppert, G Chen, M Sarr, C Sahin, K Nordling, N Kronqvist, ... The FEBS Journal 287 (13), 2823-2833, 2020 | 14 | 2020 |
| Functionalization of amyloid fibrils via the Bri2 BRICHOS domain H Biverstål, R Kumar, AK Schellhaus, M Sarr, NP Dantuma, A Abelein, ... Scientific Reports 10 (1), 21765, 2020 | 12 | 2020 |
| Smallest secondary nucleation competent Aβ aggregates probed by an ATP-independent molecular chaperone domain A Leppert, A Tiiman, N Kronqvist, M Landreh, A Abelein, V Vukojević, ... Biochemistry 60 (9), 678-688, 2021 | 11 | 2021 |
| Intravenous treatment with a molecular chaperone designed against β-amyloid toxicity improves Alzheimer’s disease pathology in mouse models S Manchanda, L Galan-Acosta, A Abelein, S Tambaro, G Chen, P Nilsson, ... Molecular Therapy, 2022 | 6 | 2022 |
| Amyloid fibril formation of Arctic amyloid-β 1–42 peptide is efficiently inhibited by the BRICHOS domain X Zhong, R Kumar, Y Wang, H Biverstål, C Ingeborg Jegerschöld, ... ACS Chemical Biology 17 (8), 2201-2211, 2022 | 5 | 2022 |
| Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration M Brackhan, G Calza, K Lundgren, P Bascunana, T Brüning, R Soliymani, ... EMBO reports 23 (7), e54405, 2022 | 4 | 2022 |
| A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder M Kaldmäe, T Vosselman, X Zhong, D Lama, G Chen, M Saluri, ... Structure 30 (5), 733-742. e7, 2022 | 4 | 2022 |
