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Doug W. Chan
Doug W. Chan
Assistant Professor, Baylor College of Medicine
Verifierad e-postadress på bcm.edu
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ATM associates with and phosphorylates p53: mapping the region of interaction
KE Keating, S Kozlov, S Scott, M Gatei, K Hobson, Y Taya, B Gabrielli, ...
Nature genetics 20 (4), 398-400, 1998
6541998
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line
SP Lees-Miller, R Godbout, DW Chan, M Weinfeld, RS Day III, GM Barron, ...
Science 267 (5201), 1183-1185, 1995
6431995
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
DW Chan, BPC Chen, S Prithivirajsingh, A Kurimasa, MD Story, J Qin, ...
Genes & development 16 (18), 2333-2338, 2002
6162002
PTOP interacts with POT1 and regulates its localization to telomeres
D Liu, A Safari, MS O'Connor, DW Chan, A Laegeler, J Qin, Z Songyang
Nature cell biology 6 (7), 673-680, 2004
5832004
Purification and functional characterization of the human N‐CoR complex: the roles of HDAC3, TBL1 and TBLR1
HG Yoon, DW Chan, ZQ Huang, J Li, JD Fondell, J Qin, J Wong
The EMBO journal, 2003
5322003
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso
HG Yoon, DW Chan, AB Reynolds, J Qin, J Wong
Molecular cell 12 (3), 723-734, 2003
5062003
Analysis of the human endogenous coregulator complexome
A Malovannaya, RB Lanz, SY Jung, Y Bulynko, NT Le, DW Chan, C Ding, ...
Cell 145 (5), 787-799, 2011
4892011
DNA‐dependent protein kinase catalytic subunit: a target for an ICE‐like protease in apoptosis.
Q Song, SP Lees‐Miller, S Kumar, Z Zhang, DW Chan, GC Smith, ...
The EMBO journal 15 (13), 3238-3246, 1996
4761996
Integrated proteogenomic characterization of clear cell renal cell carcinoma
DJ Clark, SM Dhanasekaran, F Petralia, J Pan, X Song, Y Hu, ...
Cell 179 (4), 964-983. e31, 2019
4392019
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks
BPC Chen, DW Chan, J Kobayashi, S Burma, A Asaithamby, ...
Journal of Biological Chemistry 280 (15), 14709-14715, 2005
3942005
The DNA-dependent Protein Kinase Is Inactivated by Autophosphorylation of the Catalytic Subunit (∗)
DW Chan, SP Lees-Miller
Journal of Biological Chemistry 271 (15), 8936-8941, 1996
3741996
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks
JI Loizou, SF El-Khamisy, A Zlatanou, DJ Moore, DW Chan, J Qin, ...
Cell 117 (1), 17-28, 2004
3722004
Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation
J McCready, JD Sims, D Chan, DG Jay
BMC cancer 10, 1-10, 2010
3512010
Proteogenomic characterization of endometrial carcinoma
Y Dou, EA Kawaler, DC Zhou, MA Gritsenko, C Huang, L Blumenberg, ...
Cell 180 (4), 729-748. e26, 2020
3212020
Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
SM Yannone, S Roy, DW Chan, MB Murphy, S Huang, J Campisi, ...
Journal of Biological Chemistry 276 (41), 38242-38248, 2001
2772001
Utilization of oriented peptide libraries to identify substrate motifs selected by ATM
T O'Neill, AJ Dwyer, Y Ziv, DW Chan, SP Lees-Miller, RH Abraham, JH Lai, ...
Journal of Biological Chemistry 275 (30), 22719-22727, 2000
2522000
DNA‐PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation‐dependent manner
EJ Park, DW Chan, JH Park, MA Oettinger, J Kwon
Nucleic acids research 31 (23), 6819-6827, 2003
1932003
DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer
DW Chan, R Ye, CJ Veillette, SP Lees-Miller
Biochemistry 38 (6), 1819-1828, 1999
1791999
A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment
H Luo, DW Chan, T Yang, M Rodriguez, BPC Chen, M Leng, JJ Mu, ...
Molecular and cellular biology 24 (19), 8356-8365, 2004
1642004
Purification and characterization of ATM from human placenta: a manganese-dependent, wortmannin-sensitive serine/threonine protein kinase
DW Chan, SC Son, W Block, R Ye, KK Khanna, MS Wold, P Douglas, ...
Journal of Biological Chemistry 275 (11), 7803-7810, 2000
1602000
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