Följ
Dina ElHarouni
Dina ElHarouni
Dana Farber Cancer Institute, Harvard Medical School
Verifierad e-postadress på dfci.harvard.edu
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Functional therapeutic target validation using pediatric zebrafish xenograft models
C Gatzweiler, J Ridinger, S Herter, XF Gerloff, D ElHarouni, Y Berker, ...
Cancers 14 (3), 849, 2022
162022
Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM
H Peterziel, N Jamaladdin, D ElHarouni, XF Gerloff, S Herter, P Fiesel, ...
NPJ precision oncology 6 (1), 94, 2022
132022
iTReX: Interactive exploration of mono-and combination therapy dose response profiling data
D ElHarouni, Y Berker, H Peterziel, A Gopisetty, L Turunen, S Kreth, ...
Pharmacological research 175, 105996, 2022
132022
Patient-by-Patient deep transfer learning for drug-response profiling using confocal fluorescence microscopy of pediatric patient-derived tumor-cell spheroids
Y Berker, D ElHarouni, H Peterziel, P Fiesel, O Witt, I Oehme, M Schlesner, ...
IEEE Transactions on Medical Imaging 41 (12), 3981-3999, 2022
62022
A pharmacogenetic study of VDR fok1 and TYMS polymorphisms and their association with glucocorticoid-induced osteonecrosis in Egyptian children with acute lymphoblastic leukemia
D ElHarouni, D Yassin, N Ali, S Gohar, I Zaky, H Adwan, I Sidhom
Frontiers in Oncology 8, 541, 2018
52018
Early Metastasis in Colorectal Cancer Poses an Option for New Diagnostic and Treatment Strategies
H Adwan, D Elharouni, D Habashy, N Banna, R Georges, A Pervaiz, ...
Cancer Metastasis, 2018
32018
Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells
S Zeuner, J Vollmer, R Sigaud, S Oppermann, H Peterziel, D ElHarouni, ...
Journal of Neuro-oncology, 1-14, 2024
12024
Synergistic drug combinations for the treatment of MYC amplified medulloblastoma
S Zeuner, J Vollmer, S Oppermann, I Oehme, H Peterziel, D ElHarouni, ...
Klinische Pädiatrie 235 (06), 2023
2023
OTHR-04. DEVELOPMENT OF A FUNCTIONAL PLATFORM FOR REAL-TIME PERSONALIZED DRUG SENSITIVITY PROFILING OF PATIENT-DERIVED 3D FRESH TUMOR TISSUE CULTURES IN THE PEDIATRIC PRECISION …
H Peterziel, N Jamaladdin, D ElHarouni, XF Gerloff, S Herter, P Fiesel, ...
Neuro-Oncology 25 (Supplement_1), i74-i75, 2023
2023
Radiosensitivity in pediatric solid tumors
C Gade, R Imle, D ElHarouni, I Oehme, A Banito, KW Pajtler
Klinische Pädiatrie 235 (03), 0016, 2023
2023
Predicting response to PARP inhibitors in pediatric cancer via synthetic lethal networks
M Nagy, F Schischlik, K Wang, NU Nair, EM Gertz, LR Pal, N Jaeger, ...
Cancer Research 83 (7_Supplement), 3118-3118, 2023
2023
The role of key pharmacodynamic and pharmacokinetic parameters in drug response prediction of pediatric tumors in the precision oncology study INFORM
N Jamaladdin
2023
THE ROLE OF KEY PHARMACODYNAMIC AND PHARMACOKINETIC PARAMETERS IN DRUG RESPONSE PREDICTION OF PEDIATRIC TUMORS IN THE PRECISION ONCOLOGY STUDY INFORM
N Jamaladdin, H Peterziel, D ElHarouni, N Jaeger, T Holland-Letz, ...
NEURO-ONCOLOGY 24, 33-34, 2022
2022
Multiomics analysis of pediatric solid tumors within the INFORM precision oncology study: From functional drug profiling to biomarker identification.
D ElHarouni, H Peterziel, K Schramm, T Milde, S Oppermann, I Oehme, ...
Journal of Clinical Oncology 40 (16_suppl), 10036-10036, 2022
2022
Therapy Response Scoring and Multi-omics Biomarker Identification for Precision Treatments in Pediatric Solid Tumors
D ElHarouni
Ruprecht-Karls-University Heidelberg, 2022
2022
IMAGE-BASED DRUG RESPONSE PROFILING FROM PEDIATRIC TUMOR CELL SPHEROIDS USING PATIENT-BY-PATIENT DEEP TRANSFER LEARNING
Y Berker, D ElHarouni, H Peterziel, I Oehme, M Schlesner, O Witt, ...
NEURO-ONCOLOGY 23, 36-36, 2021
2021
EMBR-11. SYNERGISTIC DRUG COMBINATIONS FOR THE TREATMENT OF MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA
S Zeuner, J Vollmer, H Peterziel, R Sigaud, S Oppermann, D ElHarouni, ...
Neuro-Oncology 23 (Supplement_1), i7-i8, 2021
2021
Enhancing the effect of class I HDAC inhibition in MYC amplified group 3 medulloblastoma with novel drug combinations
S Zeuner, J Ecker, J Vollmer, S Oppermann, I Oehme, H Peterziel, ...
Klinische Pädiatrie 232 (03), 2020
2020
An integrated bioinformatics pipeline for functional drug response profiling in pediatric precision oncology
D ElHarouni, O Witt, M Schlesner, S Oppermann
PEMED 2020, 2020
2020
Bridging the Gap in Personalized Oncology using Omics Data and Epidemiology
D El Harouni, H Adwan, F Nabil
Novel Approaches in Cancer Study, 2018
2018
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Artiklar 1–20