Tissue factor-factor VIIa–specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration GM Hjortoe, LC Petersen, T Albrektsen, BB Sorensen, PL Norby, ... Blood 103 (8), 3029-3037, 2004 | 335 | 2004 |
Transcriptional program induced by factor VIIa‐tissue factor, PAR1 and PAR2 in MDA‐MB‐231 cells T Albrektsen, BB Sørensen, GM Hjortø, J Fleckner, LVM Rao, LC Petersen Journal of thrombosis and haemostasis 5 (8), 1588-1597, 2007 | 134 | 2007 |
Differential CCR7 targeting in dendritic cells by three naturally occurring CC-chemokines GM Hjortø, O Larsen, A Steen, V Daugvilaite, C Berg, S Fares, M Hansen, ... Frontiers in Immunology 7, 218657, 2016 | 71 | 2016 |
In-chip fabrication of free-form 3D constructs for directed cell migration analysis MH Olsen, GM Hjortø, M Hansen, Ö Met, IM Svane, NB Larsen Lab on a Chip 13 (24), 4800-4809, 2013 | 69 | 2013 |
Regulation of chemotaxis by the cytoplasmic domain of tissue factor A Siegbahn, M Johnell, BB Sorensen, LC Petersen, CH Heldin Thrombosis and haemostasis 93 (01), 27-34, 2005 | 57 | 2005 |
Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo K Spiess, MG Jeppesen, M Malmgaard-Clausen, K Krzywkowski, K Dulal, ... Proceedings of the National Academy of Sciences 112 (27), 8427-8432, 2015 | 54 | 2015 |
Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells X Jiang, S Zhu, TS Panetti, ME Bromberg Thrombosis and haemostasis 100 (07), 127-133, 2008 | 52 | 2008 |
Dendritic cells and CCR7 expression: an important factor for autoimmune diseases, chronic inflammation, and cancer EP Brandum, AS Jørgensen, MM Rosenkilde, GM Hjortø International journal of molecular sciences 22 (15), 8340, 2021 | 48 | 2021 |
Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy M Hansen, GM Hjortø, M Donia, Ö Met, NB Larsen, MH Andersen, ... Vaccine 31 (4), 639-646, 2013 | 45 | 2013 |
Biased signaling of G protein-coupled receptors–From a chemokine receptor CCR7 perspective AS Jørgensen, MM Rosenkilde, GM Hjortø General and comparative endocrinology 258, 4-14, 2018 | 39 | 2018 |
Probing biased signaling in chemokine receptors RM Amarandi, GM Hjortø, MM Rosenkilde, S Karlshøj Methods in enzymology 570, 155-186, 2016 | 32 | 2016 |
Factor VIIa binding and internalization in hepatocytes G Hjortoe, BB Sorensen, LC Petersen, LVM Rao Journal of Thrombosis and Haemostasis 3 (10), 2264-2273, 2005 | 31 | 2005 |
Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface GM Hjortø, K Kiilerich-Pedersen, D Selmeczi, TN Kledal, NB Larsen Journal of General Virology 94 (5), 1111-1120, 2013 | 29 | 2013 |
CCL19 with CCL21-tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells AS Jørgensen, PE Adogamhe, JM Laufer, DF Legler, CT Veldkamp, ... Journal of leukocyte biology 104 (2), 401-411, 2018 | 28 | 2018 |
GLP-1 Val8: a biased GLP-1R agonist with altered binding kinetics and impaired release of pancreatic hormones in rats WJC van der Velden, FX Smit, CB Christiansen, TC Møller, GM Hjortø, ... ACS Pharmacology & Translational Science 4 (1), 296-313, 2021 | 27 | 2021 |
Functional identification and monitoring of individual α and β cells in cultured mouse islets of Langerhans GM Hjortø, GM Hagel, BR Terry, O Thastrup, POG Arkhammar Acta Diabetologica 41, 185-193, 2004 | 27 | 2004 |
Signaling via G proteins mediates tumorigenic effects of GPR87 KN Arfelt, S Fares, AH Sparre-Ulrich, GM Hjortø, LS Gasbjerg, ... Cellular Signalling 30, 9-18, 2017 | 24 | 2017 |
Biased action of the CXCR4-targeting drug plerixafor is essential for its superior hematopoietic stem cell mobilization AS Jørgensen, V Daugvilaite, K De Filippo, C Berg, M Mavri, ... Communications biology 4 (1), 569, 2021 | 23 | 2021 |
Arrestin‐independent constitutive endocytosis of GPR125/ADGRA3 K Spiess, SO Bagger, LJ Torz, KHR Jensen, AL Walser, JM Kvam, ... Annals of the New York Academy of Sciences 1456 (1), 186-199, 2019 | 23 | 2019 |
Biased signaling of CCL21 and CCL19 does not rely on N-terminal differences, but markedly on the chemokine core domains and extracellular loop 2 of CCR7 AS Jørgensen, O Larsen, E Uetz-von Allmen, M Lückmann, DF Legler, ... Frontiers in immunology 10, 2156, 2019 | 23 | 2019 |