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Jordan Jarjour
Jordan Jarjour
CSO
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Title
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Cited by
Year
Tracking genome engineering outcome at individual DNA breakpoints
MT Certo, BY Ryu, JE Annis, M Garibov, J Jarjour, DJ Rawlings, ...
Nature methods 8 (8), 671-676, 2011
3802011
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template
BD Sather, GS Romano Ibarra, K Sommer, G Curinga, M Hale, IF Khan, ...
Science translational medicine 7 (307), 307ra156-307ra156, 2015
2722015
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
S Boissel, J Jarjour, A Astrakhan, A Adey, A Gouble, P Duchateau, ...
Nucleic acids research 42 (4), 2591-2601, 2014
2472014
Fanconi anemia gene editing by the CRISPR/Cas9 system
MJ Osborn, R Gabriel, BR Webber, AP DeFeo, AN McElroy, J Jarjour, ...
Human gene therapy 26 (2), 114-126, 2015
1272015
Exploitation of binding energy for catalysis and design
SB Thyme, J Jarjour, R Takeuchi, JJ Havranek, J Ashworth, ...
Nature 461 (7268), 1300-1304, 2009
1092009
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display
J Jarjour, H West-Foyle, MT Certo, CG Hubert, L Doyle, MM Getz, ...
Nucleic acids research 37 (20), 6871-6880, 2009
692009
Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization
WH Leung, J Gay, U Martin, TE Garrett, HM Horton, MT Certo, BR Blazar, ...
JCI insight 4 (11), 2019
602019
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
S Baxter, AR Lambert, R Kuhar, J Jarjour, N Kulshina, F Parmeggiani, ...
Nucleic acids research 40 (16), 7985-8000, 2012
572012
LAHEDES: the LAGLIDADG homing endonuclease database and engineering server
GK Taylor, LH Petrucci, AR Lambert, SK Baxter, J Jarjour, BL Stoddard
Nucleic acids research 40 (W1), W110-W116, 2012
562012
Multipartite signaling proteins and uses thereof
J Jarjour, A Astrakhan, M Certo
US Patent 10,428,142, 2019
472019
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
YS Chan, R Takeuchi, J Jarjour, DS Huen, BL Stoddard, S Russell
PloS one 8 (9), e74254, 2013
442013
Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space
K Jacoby, M Metzger, BW Shen, MT Certo, J Jarjour, BL Stoddard, ...
Nucleic acids research 40 (11), 4954-4964, 2012
392012
Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases
P Volna, J Jarjour, S Baxter, SR Roffler, RJ Monnat, BL Stoddard, ...
Nucleic acids research 35 (8), 2748-2758, 2007
382007
Indirect DNA sequence recognition and its impact on nuclease cleavage activity
AR Lambert, JP Hallinan, BW Shen, JK Chik, JM Bolduc, N Kulshina, ...
Structure 24 (6), 862-873, 2016
272016
A laglidadg homing endonuclease cleaving the cc chemokine receptor type-5 (ccr5) gene and uses thereof
J Jarjour, A Astrakhan
232014
Efficient modification of the CCR5 locus in primary human T cells with megaTAL nuclease establishes HIV-1 resistance
GSR Ibarra, B Paul, BD Sather, PM Younan, K Sommer, JP Kowalski, ...
Molecular Therapy-Nucleic Acids 5, 2016
222016
Multipartite signaling proteins and uses thereof
J Jarjour, A Astrakhan, M Certo
172015
Flow cytometric assays for interrogating LAGLIDADG homing endonuclease DNA-binding and cleavage properties
SK Baxter, AR Lambert, AM Scharenberg, J Jarjour
Enzyme Engineering: Methods and Protocols, 45-61, 2013
172013
LAGLIDADG homing endonuclease cleaving the T cell receptor alpha gene and uses thereof
J Jarjour, A Astrakhan
US Patent 10,000,746, 2018
122018
Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity
R Werther, JP Hallinan, AR Lambert, K Havens, M Pogson, J Jarjour, ...
Nucleic Acids Research 45 (14), 8621-8634, 2017
122017
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