Sylvie Alonso
Sylvie Alonso
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The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination
K Pethe, S Alonso, F Biet, G Delogu, MJ Brennan, C Locht, FD Menozzi
Nature 412 (6843), 190-194, 2001
The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis
SPS Rao, S Alonso, L Rand, T Dick, K Pethe
Proceedings of the National Academy of Sciences 105 (33), 11945-11950, 2008
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
K Pethe, P Bifani, J Jang, S Kang, S Park, S Ahn, J Jiricek, J Jung, ...
Nature medicine 19 (9), 1157-1160, 2013
Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy
S Alonso, K Pethe, DG Russell, GE Purdy
Proceedings of the National Academy of Sciences 104 (14), 6031-6036, 2007
Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation
K Pethe, DL Swenson, S Alonso, J Anderson, C Wang, DG Russell
Proceedings of the National Academy of Sciences 101 (37), 13642-13647, 2004
Identification of neutralizing linear epitopes from the VP1 capsid protein of Enterovirus 71 using synthetic peptides
DGW Foo, S Alonso, MC Phoon, NP Ramachandran, VTK Chow, CL Poh
Virus research 125 (1), 61-68, 2007
The structural basis for serotype-specific neutralization of dengue virus by a human antibody
EP Teoh, P Kukkaro, EW Teo, APC Lim, TT Tan, A Yip, W Schul, M Aung, ...
Science translational medicine 4 (139), 139ra83-139ra83, 2012
Passive protection against lethal enterovirus 71 infection in newborn mice by neutralizing antibodies elicited by a synthetic peptide
DGW Foo, S Alonso, VTK Chow, CL Poh
Microbes and infection 9 (11), 1299-1306, 2007
Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin
S Temmerman, K Pethe, M Parra, S Alonso, C Rouanet, T Pickett, ...
Nature medicine 10 (9), 935-941, 2004
Sustained high levels of interleukin-6 contribute to the pathogenesis of enterovirus 71 in a neonate mouse model
WX Khong, DGW Foo, SL Trasti, EL Tan, S Alonso
Journal of virology 85 (7), 3067-3076, 2011
A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection
WX Khong, B Yan, H Yeo, EL Tan, JJ Lee, JKW Ng, VT Chow, S Alonso
Journal of virology 86 (4), 2121-2131, 2012
Role of adhesin release for mucosal colonization by a bacterial pathogen
L Coutte, S Alonso, N Reveneau, E Willery, B Quatannens, C Locht, ...
The Journal of experimental medicine 197 (6), 735-742, 2003
A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice
GK Tan, JKW Ng, SL Trasti, W Schul, G Yip, S Alonso
PLoS Negl Trop Dis 4 (4), e672, 2010
New virulence-activated and virulence-repressed genes identified by systematic gene inactivation and generation of transcriptional fusions in Bordetella pertussis
R Antoine, S Alonso, D Raze, L Coutte, S Lesjean, E Willery, C Locht, ...
Journal of Bacteriology 182 (20), 5902-5905, 2000
Upconversion nanoparticles for sensitive and in-depth detection of Cu 2+ ions
C Li, J Liu, S Alonso, F Li, Y Zhang
Nanoscale 4 (19), 6065-6071, 2012
First experimental in vivo model of enhanced dengue disease severity through maternally acquired heterotypic dengue antibodies
JKW Ng, SL Zhang, HC Tan, B Yan, JMM Gomez, WY Tan, JH Lam, ...
PLoS Pathog 10 (4), e1004031, 2014
Structure-guided design of an anti-dengue antibody directed to a non-immunodominant epitope
LN Robinson, K Tharakaraman, KJ Rowley, VV Costa, KR Chan, ...
Cell 162 (3), 493-504, 2015
Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid-and reactive nitrogen species stresses
MP Tan, P Sequeira, WW Lin, WY Phong, P Cliff, SH Ng, BH Lee, ...
PLoS One 5 (10), e13356, 2010
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection
NP Kalia, EJ Hasenoehrl, NB Ab Rahman, VH Koh, MLT Ang, DR Sajorda, ...
Proceedings of the National Academy of Sciences 114 (28), 7426-7431, 2017
Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria
KS Tan, KO Lee, KC Low, AM Gamage, Y Liu, GYG Tan, HQV Koh, ...
The Journal of clinical investigation 122 (6), 2289-2300, 2012
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