Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ... The Journal of Clinical Investigation 130 (2), 981-997, 2020 | 164 | 2020 |
Property focused structure-based optimization of small molecule inhibitors of the protein–protein interaction between menin and mixed lineage leukemia (MLL) D Borkin, J Pollock, K Kempinska, T Purohit, X Li, B Wen, T Zhao, H Miao, ... Journal of medicinal chemistry 59 (3), 892-913, 2016 | 75 | 2016 |
Albumin Nanoparticle of Paclitaxel (Abraxane) Decreases while Taxol Increases Breast Cancer Stem Cells in Treatment of Triple Negative Breast Cancer H Yuan, H Guo, X Luan, M He, F Li, J Burnett, N Truchan, D Sun Molecular Pharmaceutics, 2020 | 64 | 2020 |
Distinct biodistribution of doxorubicin and the altered dispositions mediated by different liposomal formulations R Luo, Y Li, M He, H Zhang, H Yuan, M Johnson, M Palmisano, S Zhou, ... International journal of pharmaceutics 519 (1-2), 1-10, 2017 | 61 | 2017 |
Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase JT Madak, CR Cuthbertson, Y Miyata, S Tamura, EM Petrunak, ... Journal of medicinal chemistry 61 (12), 5162-5186, 2018 | 54 | 2018 |
Complexity of Blocking Bivalent Protein–Protein Interactions: Development of a Highly Potent Inhibitor of the Menin–Mixed-Lineage Leukemia Interaction D Borkin, S Klossowski, J Pollock, H Miao, BM Linhares, K Kempinska, ... Journal of medicinal chemistry 61 (11), 4832-4850, 2018 | 51 | 2018 |
Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy HJ Paholak, NO Stevers, H Chen, JP Burnett, M He, H Korkaya, ... Biomaterials 104, 145-157, 2016 | 50 | 2016 |
Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy H Chen, X Luan, HJ Paholak, JP Burnett, NO Stevers, ... Nanomedicine 15 (1), 77-92, 2020 | 41 | 2020 |
Therapeutic targeting of TP53-mutated acute myeloid leukemia by inhibiting HIF-1α with echinomycin Y Wang, Y Liu, C Bailey, H Zhang, M He, D Sun, P Zhang, B Parkin, ... Oncogene 39 (14), 3015-3027, 2020 | 29 | 2020 |
Different nanoformulations alter the tissue distribution of paclitaxel, which aligns with reported distinct efficacy and safety profiles F Li, H Zhang, M He, J Liao, N Chen, Y Li, S Zhou, M Palmisano, A Yu, ... Molecular pharmaceutics 15 (10), 4505-4516, 2018 | 18 | 2018 |
Anti-infective activity of 2-cyano-3-acrylamide inhibitors with improved drug-like properties against two intracellular pathogens KD Passalacqua, ME Charbonneau, NJ Donato, HD Showalter, D Sun, ... Antimicrobial agents and chemotherapy 60 (7), 4183-4196, 2016 | 13 | 2016 |
Neonatal Fc Receptor (FcRn) Enhances Tissue Distribution and Prevents Excretion of nab-Paclitaxel F Li, H Yuan, H Zhang, M He, J Liao, N Chen, Y Li, S Zhou, M Palmisano, ... Molecular pharmaceutics 16 (6), 2385-2393, 2019 | 9 | 2019 |
Species difference in paclitaxel disposition correlated with poor pharmacological efficacy translation from mice to humans YF Li, C Zhang, S Zhou, M He, H Zhang, N Chen, F Li, X Luan, M Pai, ... Clinical pharmacology: advances and applications 10, 165, 2018 | 7 | 2018 |
Abraxane eliminates cancer stem cells in triple-negative breast cancers H Yuan, H Guo, F Li, J Burnett, M He, N Truchan, I Myers, D Sun Cancer Research 77 (13 Supplement), 4788-4788, 2017 | 1 | 2017 |
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Investigate Current Anticancer Nanomedicine Design Principles and Identify New Criteria to Improve Clinical Efficacy and Safety X Luan, H Yuan, B Wen, W Gao, H Zhang, MHY Li, F Li, JP Burnett, ... | | 2019 |
Structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and mixed lineage leukemia (MLL) J Pollock, D Borkin, K Kempinska, T Purohit, X Li, B Wen, T Zhao, H Miao, ... Cancer Research 76 (14 Supplement), 3898-3898, 2016 | | 2016 |
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