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Hassan Jumaa
Hassan Jumaa
Professor of Immunology, Ulm University
Verifierad e-postadress på uni-ulm.de - Startsida
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Testing gene function early in the B cell lineage in mb1-cre mice
E Hobeika, S Thiemann, B Storch, H Jumaa, PJ Nielsen, R Pelanda, ...
Proceedings of the National Academy of Sciences 103 (37), 13789-13794, 2006
6282006
Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
MD Minden, R Übelhart, D Schneider, T Wossning, MP Bach, M Buchner, ...
Nature 489 (7415), 309-312, 2012
6192012
Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling
S Herzog, M Reth, H Jumaa
Nature Reviews Immunology 9 (3), 195-205, 2009
4502009
Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65
H Jumaa, B Wollscheid, M Mitterer, J Wienands, M Reth, PJ Nielsen
Immunity 11 (5), 547-554, 1999
3591999
SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation
J Wienands, J Schweikert, B Wollscheid, H Jumaa, PJ Nielsen, M Reth
The Journal of experimental medicine 188 (4), 791-795, 1998
3561998
The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation
H Jumaa, PJ Nielsen
The EMBO journal 16 (16), 5077-5085, 1997
3261997
Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation
K Huck, O Feyen, T Niehues, F Rüschendorf, N Hübner, HJ Laws, ...
The Journal of clinical investigation 119 (5), 1350-1358, 2009
3192009
Yin Yang 1 is a critical regulator of B-cell development
H Liu, M Schmidt-Supprian, Y Shi, E Hobeika, N Barteneva, H Jumaa, ...
Genes & development 21 (10), 1179-1189, 2007
2782007
Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits
EC Thompson, BS Cobb, P Sabbattini, S Meixlsperger, V Parelho, ...
Immunity 26 (3), 335-344, 2007
2302007
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion
A Flemming, T Brummer, M Reth, H Jumaa
Nature immunology 4 (1), 38-43, 2003
2252003
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition
C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ...
Nature 473 (7347), 384-388, 2011
2182011
Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia
M Buchner, S Fuchs, G Prinz, D Pfeifer, K Bartholomé, M Burger, ...
Cancer research 69 (13), 5424-5432, 2009
2162009
Spleen tyrosine kinase inhibition prevents chemokine-and integrin-mediated stromal protective effects in chronic lymphocytic leukemia
M Buchner, C Baer, G Prinz, C Dierks, M Burger, T Zenz, S Stilgenbauer, ...
Blood, The Journal of the American Society of Hematology 115 (22), 4497-4506, 2010
2142010
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia
L Klemm, C Duy, I Iacobucci, S Kuchen, G von Levetzow, N Feldhahn, ...
Cancer cell 16 (3), 232-245, 2009
1972009
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
C Hurtz, K Hatzi, L Cerchietti, M Braig, E Park, Y Kim, S Herzog, ...
Journal of Experimental Medicine 208 (11), 2163-2174, 2011
1942011
Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20
H Jumaa, G Wei, PJ Nielsen
Current Biology 9 (16), 899-902, 1999
1911999
SLP-65 regulates immunoglobulin light chain gene recombination through the PI (3) K-PKB-Foxo pathway
S Herzog, E Hug, S Meixlsperger, JH Paik, RA DePinho, M Reth, ...
Nature immunology 9 (6), 623-631, 2008
1882008
Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia
H Jumaa, L Bossaller, K Portugal, B Storch, M Lotz, A Flemming, ...
Nature 423 (6938), 452-456, 2003
1602003
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia
Z Chen, S Shojaee, M Buchner, H Geng, JW Lee, L Klemm, B Titz, ...
Nature 521 (7552), 357-361, 2015
1512015
Role of PI3K in the generation and survival of B cells
M Werner, E Hobeika, H Jumaa
Immunological reviews 237 (1), 55-71, 2010
1512010
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Artiklar 1–20