| Enhanced nonenzymatic RNA copying with 2-aminoimidazole activated nucleotides L Li, N Prywes, CP Tam, DK O’flaherty, VS Lelyveld, EC Izgu, A Pal, ... Journal of the American Chemical Society 139 (5), 1810-1813, 2017 | 158 | 2017 |
| Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites L Li, MT Boniecki, JD Jaffe, BS Imai, PM Yau, ZA Luthey-Schulten, ... Proceedings of the National Academy of Sciences 108 (23), 9378-9383, 2011 | 135 | 2011 |
| Copying of mixed-sequence RNA templates inside model protocells DK O’Flaherty, NP Kamat, FN Mirza, L Li, N Prywes, JW Szostak Journal of the American Chemical Society 140 (15), 5171-5178, 2018 | 87 | 2018 |
| Common and potentially prebiotic origin for precursors of nucleotide synthesis and activation AC Fahrenbach, C Giurgiu, CP Tam, L Li, Y Hongo, M Aono, JW Szostak Journal of the American Chemical Society 139 (26), 8780-8783, 2017 | 85 | 2017 |
| The mechanism of nonenzymatic template copying with imidazole‐activated nucleotides T Walton, W Zhang, L Li, CP Tam, JW Szostak Angewandte Chemie International Edition 58 (32), 10812-10819, 2019 | 67 | 2019 |
| Structural insights into the effects of 2′-5′ linkages on the RNA duplex J Sheng, L Li, AE Engelhart, J Gan, J Wang, JW Szostak Proceedings of the National Academy of Sciences 111 (8), 3050-3055, 2014 | 56 | 2014 |
| The free energy landscape of pseudorotation in 3′–5′ and 2′–5′ linked nucleic acids L Li, JW Szostak Journal of the American Chemical Society 136 (7), 2858-2865, 2014 | 43 | 2014 |
| Uncovering the thermodynamics of monomer binding for RNA replication EC Izgu, AC Fahrenbach, N Zhang, L Li, W Zhang, AT Larsen, JC Blain, ... Journal of the American Chemical Society 137 (19), 6373-6382, 2015 | 32 | 2015 |
| Crystallographic observation of nonenzymatic RNA primer extension W Zhang, T Walton, L Li, JW Szostak Elife 7, e36422, 2018 | 31 | 2018 |
| A mechanistic explanation for the regioselectivity of nonenzymatic RNA primer extension C Giurgiu, L Li, DK O’Flaherty, CP Tam, JW Szostak Journal of the American Chemical Society 139 (46), 16741-16747, 2017 | 23 | 2017 |
| Experimental and computational evidence for a loose transition state in phosphoroimidazolide hydrolysis L Li, VS Lelyveld, N Prywes, JW Szostak Journal of the American Chemical Society 138 (12), 3986-3989, 2016 | 18 | 2016 |
| Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogens L Li, A Palencia, T Lukk, Z Li, ZA Luthey-Schulten, S Cusack, SA Martinis, ... Proceedings of the National Academy of Sciences 110 (10), 3817-3822, 2013 | 17 | 2013 |
| Duplication of leucyl-tRNA synthetase in an archaeal extremophile may play a role in adaptation to variable environmental conditions CS Weitzel, L Li, C Zhang, KK Eilts, NM Bretz, AL Gatten, RJ Whitaker, ... Journal of Biological Chemistry 295 (14), 4563-4576, 2020 | 8 | 2020 |
| Capture and Quality Control Mechanisms for Adenosine-5′-triphosphate Binding L Li, SA Martinis, Z Luthey-Schulten Journal of the American Chemical Society 135 (16), 6047-6055, 2013 | 7 | 2013 |
| Molecular trigger for pre-transfer editing pathway in Valyl-tRNA synthetase: A molecular dynamics simulation study L Li, L Yu, Q Huang Journal of Molecular Modeling 17, 555-564, 2011 | 5 | 2011 |
| 6 Crystal structure studies of RNA molecules containing 2′–5′-linkages J Sheng, L Li, AE Engelhart, JW Szostak Journal of Biomolecular Structure and Dynamics 31 (sup1), 4-4, 2013 | | 2013 |
| 8 Using pseudorotation as a reaction coordinate in free energy simulations of nucleic acids L Li, JW Szostak Journal of Biomolecular Structure and Dynamics 31 (sup1), 5-5, 2013 | | 2013 |
Jack W. SzostakMassachusetts General Hospital, Harvard, HHMIVerified email at molbio.mgh.harvard.edu
