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Itay Koren
Itay Koren
Senior Lecturer, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University
Verifierad e-postadress på biu.ac.il - Startsida
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DAP‐kinase‐mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl‐XL and induction of autophagy
E Zalckvar, H Berissi, L Mizrachy, Y Idelchuk, I Koren, M Eisenstein, ...
EMBO reports 10 (3), 285-292, 2009
7222009
Quantitative proteomic atlas of ubiquitination and acetylation in the DNA damage response
AEH Elia, AP Boardman, DC Wang, EL Huttlin, RA Everley, N Dephoure, ...
Molecular cell 59 (5), 867-881, 2015
3592015
The eukaryotic proteome is shaped by E3 ubiquitin ligases targeting C-terminal degrons
I Koren, RT Timms, T Kula, Q Xu, MZ Li, SJ Elledge
Cell 173 (7), 1622-1635. e14, 2018
2182018
DAP1, a novel substrate of mTOR, negatively regulates autophagy
I Koren, E Reem, A Kimchi
Current biology 20 (12), 1093-1098, 2010
1952010
A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation
RT Timms, Z Zhang, DY Rhee, JW Harper, I Koren, SJ Elledge
Science 365 (6448), eaaw4912, 2019
1412019
Tying up loose ends: the N-degron and C-degron pathways of protein degradation
RT Timms, I Koren
Biochemical Society Transactions 48 (4), 1557-1567, 2020
552020
Promoting tumorigenesis by suppressing autophagy
I Koren, A Kimchi
Science 338 (6109), 889-890, 2012
512012
Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process
I Koren, E Reem, A Kimchi
Autophagy 6 (8), 1179-1180, 2010
462010
Molecular basis for arginine C-terminal degron recognition by Cul2FEM1 E3 ligase
X Chen, S Liao, Y Makaros, Q Guo, Z Zhu, R Krizelman, K Dahan, X Tu, ...
Nature Chemical Biology 17 (3), 254-262, 2021
322021
A model-driven methodology for exploring complex disease comorbidities applied to autism spectrum disorder and inflammatory bowel disease
J Somekh, M Peleg, A Eran, I Koren, A Feiglin, A Demishtein, R Shiloh, ...
Journal of biomedical informatics 63, 366-378, 2016
162016
Ubiquitin-independent proteasomal degradation driven by C-degron pathways
Y Makaros, A Raiff, RT Timms, AR Wagh, MI Gueta, A Bekturova, ...
Molecular Cell 83 (11), 1921-1935. e7, 2023
122023
Defining E3 ligase–substrate relationships through multiplex CRISPR screening
RT Timms, EL Mena, Y Leng, MZ Li, IA Tchasovnikarova, I Koren, ...
Nature Cell Biology 25 (10), 1535-1545, 2023
72023
Molecular basis for C-degron recognition by CRL2APPBP2 ubiquitin ligase
S Zhao, D Olmayev-Yaakobov, W Ru, S Li, X Chen, J Zhang, X Yao, ...
Proceedings of the National Academy of Sciences 120 (43), e2308870120, 2023
2023
Meet the author: Itay Koren
I Koren
Molecular Cell 83 (11), 1761-1762, 2023
2023
The hidden (degron) truth behind the degradation of DHFR disease-associated variants
I Koren
Structure 30 (9), 1219-1221, 2022
2022
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Artiklar 1–15