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Ângelo José Ribeiro Tomé
Ângelo José Ribeiro Tomé
Assistant Professor, Dept. Life Sciences, Fac. Sciences and Technology, University of Coimbra
Verifierad e-postadress på ci.uc.pt
Titel
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Adenosine receptors and brain diseases: neuroprotection and neurodegeneration
CV Gomes, MP Kaster, AR Tomé, PM Agostinho, RA Cunha
Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (5), 1380-1399, 2011
4982011
Morphological field emission-SEM study of the effect of six phosphoric acid etching agents on human dentin
J Perdigão, P Lambrechts, B Van Meerbeek, ÂR Tomé, G Vanherle, ...
Dental Materials 12 (4), 262-271, 1996
3061996
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress
MP Kaster, NJ Machado, HB Silva, A Nunes, AP Ardais, M Santana, ...
Proceedings of the National Academy of Sciences 112 (25), 7833-7838, 2015
3042015
ATP as a multi-target danger signal in the brain
RJ Rodrigues, AR Tomé, RA Cunha
Frontiers in neuroscience 9, 138219, 2015
2532015
Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction
N Rebola, AP Simões, PM Canas, AR Tomé, GM Andrade, CE Barry, ...
Journal of neurochemistry 117 (1), 100-111, 2011
2092011
Adenosine receptor antagonists including caffeine alter fetal brain development in mice
CG Silva, C Métin, W Fazeli, NJ Machado, S Darmopil, PS Launay, ...
Science translational medicine 5 (197), 197ra104-197ra104, 2013
1832013
Control of pulsatile 5‐HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics
RM Barbosa, AM Silva, AR Tomé, JA Stamford, RM Santos, LM Rosário
The Journal of physiology 510 (1), 135-143, 1998
1491998
Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
P Li, D Rial, PM Canas, JH Yoo, W Li, X Zhou, Y Wang, GJP van Westen, ...
Molecular psychiatry 20 (11), 1339-1349, 2015
1432015
Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease
D Rial, AA Castro, N Machado, P Garção, FQ Gonçalves, HB Silva, ...
PloS one 9 (12), e114216, 2014
1232014
Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models
W Li, HB Silva, J Real, YM Wang, D Rial, P Li, MP Payen, Y Zhou, ...
Neurobiology of disease 79, 70-80, 2015
1002015
Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine
FQ Gonçalves, JP Lopes, HB Silva, C Lemos, AC Silva, N Gonçalves, ...
Neurobiology of Disease 132, 104570, 2019
892019
Cell-specific Purinergic Receptors Coupled to Ca2+ Entry and Ca2+ Release from Internal Stores in Adrenal Chromaffin Cells: DIFFERENTIAL SENSITIVITY TO UTP AND SURAMIN (∗)
E Castro, J Mateo, AR Tomé, RM Barbosa, MT Miras-Portugal, ...
Journal of Biological Chemistry 270 (10), 5098-5106, 1995
781995
Single-cell fura-2 microfluorometry reveals different purinoceptor subtypes coupled to Ca2+ influx and intracellular Ca2+ release in bovine adrenal chromaffin and …
E Castro, AR Tomé, MT Miras-Portugal, LM Rosário
Pflügers Archiv 426, 524-533, 1994
631994
Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway
AP Simões, JA Duarte, F Agasse, PM Canas, AR Tomé, P Agostinho, ...
Journal of neuroinflammation 9, 1-16, 2012
622012
Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage
R Boia, F Elvas, MH Madeira, ID Aires, AC Rodrigues-Neves, P Tralhão, ...
Cell death & disease 8 (10), e3065-e3065, 2017
582017
Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate …
NJ Machado, AP Simões, HB Silva, AP Ardais, MP Kaster, P Garção, ...
Molecular neurobiology 54, 1552-1563, 2017
552017
Presynaptic adenosine A2A receptors dampen cannabinoid CB1 receptor‐mediated inhibition of corticostriatal glutamatergic transmission
SG Ferreira, FQ Gonçalves, JM Marques, ÂR Tomé, RJ Rodrigues, ...
British Journal of Pharmacology 172 (4), 1074-1086, 2015
552015
Convergence of adenosine and GABA signaling for synapse stabilization during development
F Gomez-Castro, S Zappettini, JC Pressey, CG Silva, M Russeau, ...
Science 374 (6568), eabk2055, 2021
532021
Role of adenosine in epilepsy and seizures
FC Tescarollo, DM Rombo, LK DeLiberto, DE Fedele, E Alharfoush, ...
Journal of caffeine and adenosine research 10 (2), 45-60, 2020
522020
Electrophysiological and immunocytochemical evidence for P2X purinergic receptors in pancreatic β cells
AM Silva, RJ Rodrigues, AR Tomé, RA Cunha, S Misler, LM Rosário, ...
Pancreas 36 (3), 279-283, 2008
522008
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Artiklar 1–20