| Insights into coupled folding and binding mechanisms from kinetic studies SL Shammas, MD Crabtree, L Dahal, BIM Wicky, J Clarke Journal of Biological Chemistry 291 (13), 6689-6695, 2016 | 154 | 2016 |
| Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations F Paul, C Wehmeyer, ET Abualrous, H Wu, MD Crabtree, J Schöneberg, ... Nature Communications 8, 1095, 2017 | 142 | 2017 |
| Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein: Target Affinity by Altering the Lifetime of the Bound Complex MD Crabtree, W Borcherds, A Poosapati, SL Shammas, GW Daughdrill, ... Biochemistry 56 (18), 2379-2384, 2017 | 46 | 2017 |
| Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins MD Crabtree, CATF Mendonça, QR Bubb, J Clarke Journal of Biological Chemistry 293 (25), 9718-9723, 2018 | 38 | 2018 |
| Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes SJ Bradley, C Molloy, C Bundgaard, AJ Mogg, KJ Thompson, L Dwomoh, ... Molecular pharmacology 93 (6), 645-656, 2018 | 28 | 2018 |
| GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu Protein Engineering, Design and Selection 29 (9), 339-346, 2016 | 23 | 2016 |
| 123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo G Bakker, WA Vingerhoets, JP van Wieringen, K de Bruin, J Eersels, ... J Nucl Med 56 (2), 317-322, 2015 | 19 | 2015 |
| Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates MD Crabtree, J Holland, PS Kompella, L Babl, NN Turner, AJ Baldwin, ... bioRxiv, 2020 | 12 | 2020 |
| In vitro pharmacological characterization and in vivo validation of LSN3172176 a novel M1 selective muscarinic receptor agonist tracer molecule for positron emission tomography … AJ Mogg, T Eessalu, M Johnson, R Wright, HE Sanger, H Xiou, ... The Journal of pharmacology and experimental therapeutics, 2018 | 12 | 2018 |
| Thermodynamic Mapping of Effector Protein Interfaces with RalA and RalB LJ Campbell, M Peppa, MD Crabtree, A Shafiq, NF McGough, HR Mott, ... Biochemistry 54 (6), 1380-1389, 2015 | 6 | 2015 |
| Stopped-Flow Kinetic Techniques for Studying Binding Reactions of Intrinsically Disordered Proteins. MD Crabtree, SL Shammas Methods in enzymology 611, 423-457, 2018 | 5 | 2018 |
| In Vitro Transition Temperature Measurement of Phase-Separating Proteins by Microscopy J Holland, MD Crabtree, TJ Nott Intrinsically Disordered Proteins, 703-714, 2020 | 3 | 2020 |
| Ion binding with charge inversion combined with screening modulates DEAD box helicase phase transitions MD Crabtree, J Holland, AS Pillai, PS Kompella, L Babl, NN Turner, ... Cell Reports 42 (11), 2023 | 1 | 2023 |
| Cellular Droplets Newly discovered liquid dynamics within the cytoplasm and nucleus play critical roles in cell biology M Crabtree, T Nott SCIENTIST 32 (12), 28-35, 2018 | | 2018 |
| Probing Order within Intrinsically Disordered Proteins MD Crabtree University of Cambridge, 2017 | | 2017 |
| What Encodes Coupled Folding and Binding Reactions: IDPS or Partner Proteins? MD Crabtree, CATF Mendonca, Q Bubb, SL Shammas, J Clarke Biophysical Journal 112 (3), 481a, 2017 | | 2017 |
| IDPs that Fold Upon Binding: What is the Role of the Partner Protein? SL Shammas, J Rogers, M Crabtree, J Clarke Biophysical Journal 108 (2), 228a, 2015 | | 2015 |
| Better cloning through expression MD Crabtree Science 346 (6216), 1477-1477, 2014 | | 2014 |
| Handle with Care: An Unusual Butterfly Journey MD Crabtree Science 346 (6214), 1175, 2014 | | 2014 |
| What Makes You YOU? MD Crabtree Science 346 (6214), 1178, 2014 | | 2014 |
Sarah ShammasUniversity of OxfordVerified email at bioch.ox.ac.uk
