Thomas Philips
Thomas Philips
Verifierad e-postadress på jhmi.edu
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The changing scene of amyotrophic lateral sclerosis
W Robberecht, T Philips
Nature Reviews Neuroscience 14 (4), 248-264, 2013
8982013
Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease
T Philips, W Robberecht
The Lancet Neurology 10 (3), 253-263, 2011
5332011
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ...
Nature medicine 18 (9), 1418-1422, 2012
2752012
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
T Philips, A Bento-Abreu, A Nonneman, W Haeck, K Staats, V Geelen, ...
Brain 136 (2), 471-482, 2013
1922013
Rodent models of amyotrophic lateral sclerosis
T Philips, JD Rothstein
Current protocols in pharmacology 69 (1), 5.67. 1-5.67. 21, 2015
1762015
Glial cells in amyotrophic lateral sclerosis
T Philips, JD Rothstein
Experimental neurology 262, 111-120, 2014
1642014
Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase
G Gowing, T Philips, B Van Wijmeersch, JN Audet, M Dewil, ...
Journal of Neuroscience 28 (41), 10234-10244, 2008
1622008
Oligodendroglia: metabolic supporters of neurons
T Philips, JD Rothstein
The Journal of clinical investigation 127 (9), 3271-3280, 2017
1122017
Microglial upregulation of progranulin as a marker of motor neuron degeneration
T Philips, L De Muynck, H Nguyen Thi Thu, B Weynants, P Vanacker, ...
Journal of Neuropathology & Experimental Neurology 69 (12), 1191-1200, 2010
692010
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS–FTD-linked UBQLN2 mutations
NTT Le, L Chang, I Kovlyagina, P Georgiou, N Safren, KE Braunstein, ...
Proceedings of the National Academy of Sciences 113 (47), E7580-E7589, 2016
632016
Optimizing nervous system-specific gene targeting with Cre driver lines: Prevalence of germline recombination and influencing factors
L Luo, MC Ambrozkiewicz, F Benseler, C Chen, E Dumontier, S Falkner, ...
Neuron 106 (1), 37-65. e5, 2020
312020
Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin
SJ Miller, T Philips, N Kim, R Dastgheyb, Z Chen, YC Hsieh, JG Daigle, ...
Nature neuroscience 22 (5), 741-752, 2019
262019
Preclinical models: needed in translation? A Pro/Con debate
T Philips, JD Rothstein, MA Pouladi
Movement Disorders 29 (11), 1391-1396, 2014
102014
MCT1 deletion in oligodendrocyte lineage cells causes late-onset hypomyelination and axonal degeneration
T Philips, YA Mironova, Y Jouroukhin, J Chew, S Vidensky, MH Farah, ...
Cell reports 34 (2), 108610, 2021
82021
Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin
TR Westergard, SJ Miller, T Philips, N Kim, R Dastgheyb, Z Chen, ...
GLIA 67, E737-E737, 2019
2019
Age related loss of oligodendrocyte metabolic support
T Philips, E Hughes, B Morrison, Y Lee, R Sattler, D Bergles, J Rothstein
Glia 63 (S1), E459-E459, 2015
2015
Identification and Characterization of Distinct Astroglia Subpopulations in Health and Disease
SJ Miller, Z Chen, T Philips, M Robinson, R Sattler, J Rothstein
Glia 63, E101-E102, 2015
2015
The Generation and Characterization of Oligodendroglia-Specific MCT1 Conditional Knockout Mice
Y Lee, T Philips, L Jin, BM Morrison, JD Rothstein
139th Annual Meeting of American Neurological Association (ANA 2014), S117, 2014
2014
Monocarboxylate Transporter 1 Reporter Expression in the Pathogenesis of Amyotrophic Lateral Sclerosis
T Philips, EG Hughes, Y Lee, BE Morrison, R Sattler, DE Bergles, ...
139th Annual Meeting of American Neurological Association (ANA 2014), S119, 2014
2014
Glial Glutamate and Metabolic Transporters as a Target for Neurodegenerative Therapy and Biomarkers
T Philips, R Sattler
Pathological Potential of Neuroglia, 61-88, 2014
2014
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Artiklar 1–20