| Platensimycin is a selective FabF inhibitor with potent antibiotic properties J Wang, SM Soisson, K Young, W Shoop, S Kodali, A Galgoci, R Painter, ... Nature 441 (7091), 358-361, 2006 | 1004 | 2006 |
| Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4 GR Pettit, SB Singh, E Hamel, CM Lin, DS Alberts, D Garcia-Kendal Experientia 45, 209-211, 1989 | 971 | 1989 |
| Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase SJ Darkin-Rattray, AM Gurnett, RW Myers, PM Dulski, TM Crumley, ... Proceedings of the National Academy of Sciences 93 (23), 13143-13147, 1996 | 716 | 1996 |
| Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6 GR Pettit, SB Singh, MR Boyd, E Hamel, RK Pettit, JM Schmidt, F Hogan Journal of medicinal chemistry 38 (10), 1666-1672, 1995 | 567 | 1995 |
| Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties J Wang, S Kodali, SH Lee, A Galgoci, R Painter, K Dorso, F Racine, ... Proceedings of the National Academy of Sciences 104 (18), 7612-7616, 2007 | 450 | 2007 |
| Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum GR Pettit, SB Singh, ML Niven, E Hamel, JM Schmidt Journal of natural products 50 (1), 119-131, 1987 | 445 | 1987 |
| Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. CM Lin, SB Singh, PS Chu, RO Dempcy, JM Schmidt, GR Pettit, E Hamel Molecular pharmacology 34 (2), 200-208, 1988 | 436 | 1988 |
| Empirical antibacterial drug discovery—foundation in natural products SB Singh, JF Barrett Biochemical pharmacology 71 (7), 1006-1015, 2006 | 415 | 2006 |
| Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. JB Gibbs, DL Pompliano, SD Mosser, E Rands, RB Lingham, SB Singh, ... Journal of Biological Chemistry 268 (11), 7617-7620, 1993 | 408 | 1993 |
| Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy SB Singh, H Jayasuriya, JG Ondeyka, KB Herath, C Zhang, DL Zink, ... Journal of the American Chemical Society 128 (36), 11916-11920, 2006 | 297 | 2006 |
| Antineoplastic agents. Part 189. The absolute configuration and synthesis of natural (-)-dolastatin 10 GR Pettit, SB Singh, F Hogan, P Lloyd-Williams, DL Herald, DD Burkett, ... Journal of the American Chemical Society 111 (14), 5463-5465, 1989 | 283 | 1989 |
| Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics J Wang, A Galgoci, S Kodali, KB Herath, H Jayasuriya, K Dorso, F Vicente, ... Journal of Biological Chemistry 278 (45), 44424-44428, 2003 | 271 | 2003 |
| Discovery of FabH/FabF inhibitors from natural products K Young, H Jayasuriya, JG Ondeyka, K Herath, C Zhang, S Kodali, ... Antimicrobial agents and chemotherapy 50 (2), 519-526, 2006 | 256 | 2006 |
| Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad‐spectrum antibiotic activity H Jayasuriya, KB Herath, C Zhang, DL Zink, A Basilio, O Genilloud, ... Angewandte Chemie International Edition 46 (25), 4684-4688, 2007 | 245 | 2007 |
| Antineoplastic agents, 120. Pancratium littorale GR Pettit, V Gaddamidi, DL Herald, SB Singh, GM Cragg, JM Schmidt, ... Journal of natural products 49 (6), 995-1002, 1986 | 242 | 1986 |
| What is an “ideal” antibiotic? Discovery challenges and path forward SB Singh, K Young, LL Silver Biochemical pharmacology 133, 63-73, 2017 | 234 | 2017 |
| Equisetin and a novel opposite stereochemical homolog phomasetin, two fungal metabolites as inhibitors of HIV-1 integrase SB Singh, DL Zink, MA Goetz, AW Dombrowski, JD Polishook, DJ Hazuda Tetrahedron Letters 39 (16), 2243-2246, 1998 | 209 | 1998 |
| Antineoplastic agents, 122. Constituents of Combretum caffrum GR Pettit, GM Cragg, SB Singh Journal of natural products 50 (3), 386-391, 1987 | 206 | 1987 |
| Nodulisporic Acid A, a Novel and Potent Insecticide from a Nodulisporium Sp. Isolation, Structure Determination, and Chemical Transformations JG Ondeyka, GL Helms, OD Hensens, MA Goetz, DL Zink, A Tsipouras, ... Journal of the American Chemical Society 119 (38), 8809-8816, 1997 | 195 | 1997 |
| A novel antiviral agent which inhibits the endonuclease of influenza viruses JE Tomassini, ME Davies, JC Hastings, R Lingham, M Mojena, ... Antimicrobial agents and chemotherapy 40 (5), 1189-1193, 1996 | 180 | 1996 |
Gerald BillsVisiting Scientist, Rutgers University, Department of Plant BiologyVerified email at vt.edu
