| Politics and society in contemporary Africa N Chazan, RA Mortimer, D Rothchild, P Lewis, SJ Stedman Bloomsbury Publishing, 1999 | 1357 | 1999 |
| Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes PL Roach, IJ Clifton, V Fülöp, K Harlos, GJ Barton, J Hajdu, I Andersson, ... Nature 375 (6533), 700-704, 1995 | 537 | 1995 |
| Structure of isopenicillinN synthase complexed with substrate and the mechanism ofpenicillin formation PL Roach, IJ Clifton, CMH Hensgens, N Shibata, CJ Schofield, J Hajdu, ... Nature 387 (6635), 827-830, 1997 | 525 | 1997 |
| X-ray Crystal Structure of Escherichia coli Taurine/α-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates, JM Elkins, MJ Ryle, IJ Clifton, JC Dunning Hotopp, JS Lloyd, NI Burzlaff, ... Biochemistry 41 (16), 5185-5192, 2002 | 296 | 2002 |
| The reaction cycle of isopenicillin N synthase observed by X-ray diffraction NI Burzlaff, PJ Rutledge, IJ Clifton, CMH Hensgens, M Pickford, ... Nature 401 (6754), 721-724, 1999 | 227 | 1999 |
| [FeFe]-hydrogenase cyanide ligands derived from S-adenosylmethionine-dependent cleavage of tyrosine RC Driesener, MR Challand, PL Roach, SE McGlynn, EM Shepard, ... Angewandte Chemie International Edition 49 (9), 1687-1690, 2010 | 192 | 2010 |
| [FeFe]-hydrogenase maturation: HydG-catalyzed synthesis of carbon monoxide EM Shepard, BR Duffus, SJ George, SE McGlynn, MR Challand, ... Journal of the American Chemical Society 132 (27), 9247-9249, 2010 | 178 | 2010 |
| An analysis of the feasibility of short read sequencing N Whiteford, N Haslam, G Weber, A Prügel-Bennett, JW Essex, PL Roach, ... Nucleic acids research 33 (19), e171-e171, 2005 | 178 | 2005 |
| Thin film polycrystalline silicon nanowire biosensors MMA Hakim, M Lombardini, K Sun, F Giustiniano, PL Roach, DE Davies, ... Nano letters 12 (4), 1868-1872, 2012 | 136 | 2012 |
| Bead-based immunoassays using a micro-chip flow cytometer D Holmes, JK She, PL Roach, H Morgan Lab on a Chip 7 (8), 1048-1056, 2007 | 132 | 2007 |
| Iron-sulfur center of biotin synthase and lipoate synthase S Ollagnier-de Choudens, Y Sanakis, KS Hewitson, P Roach, JE Baldwin, ... Biochemistry 39 (14), 4165-4173, 2000 | 129 | 2000 |
| Thiamine Biosynthesis in Escherichia coli: Identification of the Intermediate and By‐Product Derived from Tyrosine M Kriek, F Martins, MR Challand, A Croft, PL Roach Angewandte Chemie International Edition 46 (48), 9223-9226, 2007 | 124 | 2007 |
| X-ray crystallographic and EPR spectroscopic analysis of HydG, a maturase in [FeFe]-hydrogenase H-cluster assembly P Dinis, DLM Suess, SJ Fox, JE Harmer, RC Driesener, L De La Paz, ... Proceedings of the National Academy of Sciences 112 (5), 1362-1367, 2015 | 115 | 2015 |
| Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro M Kriek, F Martins, R Leonardi, SA Fairhurst, DJ Lowe, PL Roach Journal of Biological Chemistry 282 (24), 17413-17423, 2007 | 100 | 2007 |
| Proteins of the penicillin biosynthesis pathway CJ Schofield, JE Baldwin, MF Byford, I Clifton, J Hajdu, C Hensgens, ... Current Opinion in Structural Biology 7 (6), 857-864, 1997 | 94 | 1997 |
| Lipoyl synthase inserts sulfur atoms into an octanoyl substrate in a stepwise manner P Douglas, M Kriek, P Bryant, PL Roach Angewandte Chemie International Edition 45 (31), 5197-5199, 2006 | 93 | 2006 |
| Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli S Ollagnier-de Choudens, Y Sanakis, KS Hewitson, P Roach, E Munck, ... Journal of Biological Chemistry 277 (16), 13449-13454, 2002 | 88 | 2002 |
| Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity R Leonardi, PL Roach Journal of Biological Chemistry 279 (17), 17054-17062, 2004 | 84 | 2004 |
| Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions. RPL Harmer JE, Hiscox MJ, Dinis PC, Fox SJ, Iliopoulos A, Hussey JE, Sandy J ... Biochemical Journal 464, 123-133, 2014 | 81 | 2014 |
| Structure of a specific acyl-enzyme complex formed between β-casomorphin-7 and porcine pancreatic elastase RC Wilmouth, IJ Clifton, CV Robinson, PL Roach, RT Aplin, NJ Westwood, ... Nature structural biology 4 (6), 456-462, 1997 | 81 | 1997 |
