Flexible and accessible workflows for improved proteogenomic analysis using the Galaxy framework PD Jagtap, JE Johnson, G Onsongo, FW Sadler, K Murray, Y Wang, ... Journal of proteome research 13 (12), 5898-5908, 2014 | 99 | 2014 |
Conformational plasticity of the intracellular cavity of GPCR− G-protein complexes leads to G-protein promiscuity and selectivity M Sandhu, AM Touma, M Dysthe, F Sadler, S Sivaramakrishnan, ... Proceedings of the National Academy of Sciences 116 (24), 11956-11965, 2019 | 74 | 2019 |
Autoregulation of GPCR signalling through the third intracellular loop F Sadler, N Ma, M Ritt, Y Sharma, N Vaidehi, S Sivaramakrishnan Nature 615 (7953), 734-741, 2023 | 25 | 2023 |
β2-adrenoceptor ligand efficacy is tuned by a two-stage interaction with the Gαs C terminus K Kim, S Paulekas, F Sadler, TM Gupte, M Ritt, M Dysthe, N Vaidehi, ... Proceedings of the National Academy of Sciences 118 (11), e2017201118, 2021 | 19 | 2021 |
RNA thermometers for the PURExpress system FW Sadler, I Dodevski, CA Sarkar ACS synthetic biology 7 (1), 292-296, 2018 | 19 | 2018 |
Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting heads motif and super-relaxed state of myosin DV Rasicci, P Tiwari, R Desetty, F Sadler, S Sivaramakrishnan, RW Craig, ... Biophysical Journal 121 (3), 260a, 2022 | 11 | 2022 |
Multimodal regulation of myosin VI ensemble transport by cargo adaptor protein GIPC A Rai, R Shrivastava, D Vang, M Ritt, F Sadler, S Bhaban, M Salapaka, ... Journal of Biological Chemistry 298 (3), 2022 | 6 | 2022 |
Cellular Lipids Regulate the Conformational Ensembles of the Disordered Intracellular Loop 3 in β2 Adrenergic Receptor E Mukhaleva, T Yang, F Sadler, S Sivaramakrishnan, N Ma, N Vaidehi Biorxiv, 2023 | | 2023 |
Dynamical Basis of GPCR–G Protein Coupling Selectivity and Promiscuity N Vaidehi, F Sadler, S Sivaramakrishnan GPCRs as Therapeutic Targets 1, 373-387, 2022 | | 2022 |