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Fredrik Sadler
Fredrik Sadler
Graduate Student, University of Minnesota
Verifierad e-postadress på umn.edu
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Flexible and accessible workflows for improved proteogenomic analysis using the Galaxy framework
PD Jagtap, JE Johnson, G Onsongo, FW Sadler, K Murray, Y Wang, ...
Journal of proteome research 13 (12), 5898-5908, 2014
992014
Conformational plasticity of the intracellular cavity of GPCR− G-protein complexes leads to G-protein promiscuity and selectivity
M Sandhu, AM Touma, M Dysthe, F Sadler, S Sivaramakrishnan, ...
Proceedings of the National Academy of Sciences 116 (24), 11956-11965, 2019
742019
Autoregulation of GPCR signalling through the third intracellular loop
F Sadler, N Ma, M Ritt, Y Sharma, N Vaidehi, S Sivaramakrishnan
Nature 615 (7953), 734-741, 2023
252023
β2-adrenoceptor ligand efficacy is tuned by a two-stage interaction with the Gαs C terminus
K Kim, S Paulekas, F Sadler, TM Gupte, M Ritt, M Dysthe, N Vaidehi, ...
Proceedings of the National Academy of Sciences 118 (11), e2017201118, 2021
192021
RNA thermometers for the PURExpress system
FW Sadler, I Dodevski, CA Sarkar
ACS synthetic biology 7 (1), 292-296, 2018
192018
Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting heads motif and super-relaxed state of myosin
DV Rasicci, P Tiwari, R Desetty, F Sadler, S Sivaramakrishnan, RW Craig, ...
Biophysical Journal 121 (3), 260a, 2022
112022
Multimodal regulation of myosin VI ensemble transport by cargo adaptor protein GIPC
A Rai, R Shrivastava, D Vang, M Ritt, F Sadler, S Bhaban, M Salapaka, ...
Journal of Biological Chemistry 298 (3), 2022
62022
Cellular Lipids Regulate the Conformational Ensembles of the Disordered Intracellular Loop 3 in β2 Adrenergic Receptor
E Mukhaleva, T Yang, F Sadler, S Sivaramakrishnan, N Ma, N Vaidehi
Biorxiv, 2023
2023
Dynamical Basis of GPCR–G Protein Coupling Selectivity and Promiscuity
N Vaidehi, F Sadler, S Sivaramakrishnan
GPCRs as Therapeutic Targets 1, 373-387, 2022
2022
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Artiklar 1–9