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Keyvin DARNEY
Keyvin DARNEY
Verified email at anses.fr
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Year
Human variability in isoform-specific UDP-glucuronosyltransferases: Markers of acute and chronic exposure, polymorphisms and uncertainty factors
EEJ Kasteel, K Darney, NI Kramer, J Dorne, LS Lautz
Archives of toxicology 94, 2637-2661, 2020
362020
Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment
FM Buratti, K Darney, S Vichi, L Turco, E Di Consiglio, LS Lautz, ...
Toxicology Letters 337, 78-90, 2021
292021
Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics
EEJ Kasteel, SM Nijmeijer, K Darney, LS Lautz, JLCM Dorne, NI Kramer, ...
Archives of Toxicology 94 (12), 4055-4065, 2020
282020
Effect of high-frequency radiations on survival of the honeybee (Apis mellifera L.)
K Darney, A Giraudin, R Joseph, P Abadie, P Aupinel, A Decourtye, ...
Apidologie 47, 703-710, 2016
272016
Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment
K Darney, EEJ Kasteel, FM Buratti, L Turco, S Vichi, C Béchaux, ...
Environment international 138, 105609, 2020
242020
Human variability in polymorphic CYP2D6 metabolism: Implications for the risk assessment of chemicals in food and emerging designer drugs
K Darney, LS Lautz, C Béchaux, W Wiecek, E Testai, B Amzal, J Dorne
Environment International 156, 106760, 2021
232021
Human variability in influx and efflux transporters in relation to uncertainty factors for chemical risk assessment
K Darney, L Turco, FM Buratti, E Di Consiglio, S Vichi, AC Roudot, ...
Food and chemical toxicology 140, 111305, 2020
232020
Modelling human variability in toxicokinetic and toxicodynamic processes using Bayesian meta‐analysis, physiologically‐based modelling and in vitro systems
E Testai, C Bechaux, FM Buratti, K Darney, E Di Consiglio, EEJ Kasteel, ...
EFSA Supporting Publications 18 (4), 6504E, 2021
202021
Risk assessment of chemicals in food and feed: principles, applications and future perspectives
L Ingenbleek, LS Lautz, G Dervilly, K Darney, MC Astuto, J Tarazona, ...
202020
Aggregate exposure of the adult French population to pyrethroids
K Darney, L Bodin, M Bouchard, J Côté, JL Volatier, V Desvignes
Toxicology and Applied Pharmacology 351, 21-31, 2018
202018
Human variability in carboxylesterases and carboxylesterase-related uncertainty factors for chemical risk assessment
E Di Consiglio, K Darney, FM Buratti, L Turco, S Vichi, E Testai, LS Lautz, ...
Toxicology Letters 350, 162-170, 2021
192021
Inter-ethnic differences in CYP3A4 metabolism: A Bayesian meta-analysis for the refinement of uncertainty factors in chemical risk assessment
K Darney, E Testai, FM Buratti, E Di Consiglio, EEJ Kasteel, N Kramer, ...
Computational Toxicology 12, 100092, 2019
172019
OpenCYP: An open source database exploring human variability in activities and frequencies of polymophisms for major cytochrome P-450 isoforms across world populations
S Vichi, FM Buratti, E Di Consiglio, L Turco, LS Lautz, K Darney, ...
Toxicology Letters 350, 267-282, 2021
102021
Reconnecting exposure, toxicokinetics and toxicity in food safety: OpenFoodTox and TKplate for human health, animal health and ecological risk assessment
JL Dorne, B Amzal, N Quignot, W Wiecek, C Bechaux, K Darney, A Grech, ...
54. Congress of the European Societies of Toxicology (EUROTOX 2018) 295 …, 2018
42018
Applications of TKPlate 1.0 for toxicokinetic and toxicodynamic modelling of chemicals: Case Studies
European Food Safety Authority (EFSA), H Bossier, F Spyropoulos, ...
EFSA Supporting Publications 20 (11), 8440E, 2023
32023
TKPlate 1.0: An Open‐access platform for toxicokinetic and toxicodynamic modelling of chemicals to implement new approach methodologies in chemical risk assessment
JLCM Dorne, J Cortiñas‐Abrahantes, F Spyropoulos, K Darney, L Lautz, ...
EFSA Journal 21 (11), e211101, 2023
32023
User Guide for TKPlate 1.0: An open access platform for implementing new approach methodologies in chemical risk assessment through toxicokinetic and toxicodynamic modelling
European Food Safety Authority (EFSA), H Bossier, ...
EFSA Supporting Publications 20 (11), 8441E, 2023
32023
Towards next generation risk assessment of chemicals: bayesian meta-analysis of human variability in metabolism and transporters and application for the derivation of pathway …
K Darney
Université de Bretagne occidentale-Brest, 2020
12020
Hierarchical Bayesian meta-analysis of human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for human risk assessment
K Darney, E Testai, N Kramer, JLCM Dorne, C Bechaux
Toxicology Letters 295, S249, 2018
12018
TKPlate: a web-based open source platform for Toxicokinetic and Toxicodynamic Modelling
H Bossier, JC Abrahantes, K Darney, LS Lautz, S Vergucht, T Verbeke, ...
2023
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