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Karl Tryggvason
Karl Tryggvason
Professor, Karolinska Institute, Stockholm & Duke-NUS, Singapore
Verifierad e-postadress på tryggvason.com
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Metastatic potential correlates with enzymatic degradation of basement membrane collagen
LA Liotta, K Tryggvason, S Garbisa, I Hart, CM Foltz, S Shafie
Nature 284, 67-68, 1980
22921980
Positionally cloned gene for a novel glomerular protein—nephrin—is mutated in congenital nephrotic syndrome
M Kestilä, U Lenkkeri, M Männikkö, J Lamerdin, P McCready, H Putaala, ...
Molecular cell 1 (4), 575-582, 1998
22451998
Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma
HK Kleinman, ML McGarvey, LA Liotta, PG Robey, K Tryggvason, ...
Biochemistry 21 (24), 6188-6193, 1982
14961982
Alport's syndrome, Goodpasture's syndrome, and type IV collagen
BG Hudson, K Tryggvason, M Sundaramoorthy, EG Neilson
New England Journal of Medicine 348 (25), 2543-2556, 2003
10912003
A simplified laminin nomenclature
M Aumailley, L Bruckner-Tuderman, WG Carter, R Deutzmann, D Edgar, ...
Matrix biology 24 (5), 326-332, 2005
10192005
Identification of mutations in the COL4A5 collagen gene in Alport syndrome.
DF Barker, SL Hostikka, J Zhou, LT Chow, AR Oliphant, SC Gerken, ...
Science (New York, NY) 248 (4960), 1224, 1990
9941990
A new nomenclature for the laminins
RE Burgeson, M Chiquet, R Deutzmann, P Ekblom, J Engel, H Kleinman, ...
Matrix Biology 14 (3), 209-211, 1994
9231994
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
Z Zhou, SS Apte, R Soininen, R Cao, GY Baaklini, RW Rauser, J Wang, ...
Proceedings of the National Academy of Sciences 97 (8), 4052-4057, 2000
9152000
Nephrin is specifically located at the slit diaphragm of glomerular podocytes
V Ruotsalainen, P Ljungberg, J Wartiovaara, U Lenkkeri, M Kestilä, ...
Proceedings of the National Academy of Sciences 96 (14), 7962-7967, 1999
8801999
X-linked Alport syndrome natural history in 195 families and genotype-phenotype correlations in males
JP JAIS, B KNEBELMANN, I GIATRAS, M DE MARCHI, G RIZZONI, ...
Journal of the American Society of Nephrology 11 (4), 649-657, 2000
778*2000
Mutations in the laminin α2–chain gene (LAMA2) cause merosin–deficient congenital muscular dystrophy
A Helbling-Leclerc, X Zhang, H Topaloglu, C Cruaud, F Tesson, ...
Nature genetics 11 (2), 216-218, 1995
7091995
Hereditary proteinuria syndromes and mechanisms of proteinuria
K Tryggvason, J Patrakka, J Wartiovaara
New England Journal of Medicine 354 (13), 1387-1401, 2006
7082006
Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed
E Morgunova, A Tuuttila, U Bergmann, M Isupov, Y Lindqvist, G Schneider, ...
Science 284 (5420), 1667-1670, 1999
7031999
Genomic instability in laminopathy-based premature aging
B Liu, J Wang, KM Chan, WM Tjia, W Deng, X Guan, J Huang, KM Li, ...
Nature medicine 11 (7), 780-785, 2005
6992005
Proteolytic degradation of extracellular matrix in tumor invasion
K Tryggvason, M Höyhtyä, T Salo
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 907 (3), 191-217, 1987
6751987
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511
S Rodin, A Domogatskaya, S Ström, EM Hansson, KR Chien, J Inzunza, ...
Nature biotechnology 28 (6), 611, 2010
6122010
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase–deficient mice
AM Pendás, Z Zhou, J Cadiñanos, JMP Freije, J Wang, K Hultenby, ...
Nature genetics 31 (1), 94-99, 2002
6042002
The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death
H Putaala, R Soininen, P Kilpeläinen, J Wartiovaara, K Tryggvason
Human molecular genetics 10 (1), 1-8, 2001
5942001
The vascular basement membrane: a niche for insulin gene expression and β cell proliferation
G Nikolova, N Jabs, I Konstantinova, A Domogatskaya, K Tryggvason, ...
Developmental cell 10 (3), 397-405, 2006
5892006
Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages
O Elomaa, M Kangas, C Sahlberg, J Tuukkanen, R Sormunen, A Liakka, ...
Cell 80 (4), 603-609, 1995
5731995
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