Pere Puigserver
Pere Puigserver
Professor of Cell and Cancer Biology, Harvard Medical School
Verifierad e-postadress på dfci.harvard.edu - Startsida
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PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
VK Mootha, CM Lindgren, KF Eriksson, A Subramanian, S Sihag, J Lehar, ...
Nature genetics 34 (3), 267-273, 2003
63582003
Resveratrol improves health and survival of mice on a high-calorie diet
JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ...
Nature 444 (7117), 337-342, 2006
45892006
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
P Puigserver, Z Wu, CW Park, R Graves, M Wright, BM Spiegelman
Cell 92 (6), 829-839, 1998
39041998
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
M Lagouge, C Argmann, Z Gerhart-Hines, H Meziane, C Lerin, F Daussin, ...
Cell 127 (6), 1109-1122, 2006
38832006
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
Z Wu, P Puigserver, U Andersson, C Zhang, G Adelmant, V Mootha, ...
Cell 98 (1), 115-124, 1999
37961999
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers, C Lerin, W Haas, SP Gygi, BM Spiegelman, P Puigserver
Nature 434 (7029), 113-118, 2005
30642005
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
J Lin, H Wu, PT Tarr, CY Zhang, Z Wu, O Boss, LF Michael, P Puigserver, ...
Nature 418 (6899), 797-801, 2002
25402002
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
C Cantó, Z Gerhart-Hines, JN Feige, M Lagouge, L Noriega, JC Milne, ...
Nature 458 (7241), 1056-1060, 2009
24802009
Transcriptional regulation of adipogenesis
ED Rosen, CJ Walkey, P Puigserver, BM Spiegelman
Genes & development 14 (11), 1293-1307, 2000
21722000
Transcriptional regulation of adipogenesis
ED Rosen, CJ Walkey, P Puigserver, BM Spiegelman
Genes & development 14 (11), 1293-1307, 2000
21722000
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α): transcriptional coactivator and metabolic regulator
P Puigserver, BM Spiegelman
Endocrine reviews 24 (1), 78-90, 2003
20872003
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
JC Yoon, P Puigserver, G Chen, J Donovan, Z Wu, J Rhee, G Adelmant, ...
Nature 413 (6852), 131-138, 2001
19542001
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
S Herzig, F Long, US Jhala, S Hedrick, R Quinn, A Bauer, D Rudolph, ...
Nature 413 (6852), 179-183, 2001
14052001
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
P Puigserver, J Rhee, J Donovan, CJ Walkey, JC Yoon, F Oriente, ...
Nature 423 (6939), 550-555, 2003
13082003
mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
JT Cunningham, JT Rodgers, DH Arlow, F Vazquez, VK Mootha, ...
nature 450 (7170), 736-740, 2007
12142007
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
Z Gerhart‐Hines, JT Rodgers, O Bare, C Lerin, SH Kim, R Mostoslavsky, ...
The EMBO journal 26 (7), 1913-1923, 2007
11932007
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
D Kim, MD Nguyen, MM Dobbin, A Fischer, F Sananbenesi, JT Rodgers, ...
The EMBO journal 26 (13), 3169-3179, 2007
10052007
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARγ coactivator-1
P Puigserver, J Rhee, J Lin, Z Wu, JC Yoon, CY Zhang, S Krauss, ...
Molecular cell 8 (5), 971-982, 2001
7942001
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
ZT Schafer, AR Grassian, L Song, Z Jiang, Z Gerhart-Hines, HY Irie, ...
Nature 461 (7260), 109-113, 2009
7832009
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
LF Michael, Z Wu, RB Cheatham, P Puigserver, G Adelmant, JJ Lehman, ...
Proceedings of the National Academy of Sciences 98 (7), 3820-3825, 2001
7562001
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