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Nikhil R Gandasi
Nikhil R Gandasi
Assistant Professor, Indian Institute of Science (IISc), India and Visiting researcher, Gothenburg
Verifierad e-postadress på mcb.uu.se - Startsida
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Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site
NR Gandasi, S Barg
Nature communications 5 (1), 1-14, 2014
1132014
Ca2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetes
NR Gandasi, P Yin, M Riz, MV Chibalina, G Cortese, PE Lund, V Matveev, ...
The Journal of clinical investigation 127 (6), 2353-2364, 2017
722017
Glucose-dependent granule docking limits insulin secretion and is decreased in human type 2 diabetes
NR Gandasi, P Yin, M Omar-Hmeadi, EO Laakso, P Vikman, S Barg
Cell metabolism 27 (2), 470-478. e4, 2018
632018
In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis
V Petrenko, NR Gandasi, D Sage, A Tengholm, S Barg, C Dibner
Proceedings of the National Academy of Sciences 117 (5), 2484-2495, 2020
522020
The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events
U Krus, BC King, V Nagaraj, NR Gandasi, J Sjölander, P Buda, ...
Cell metabolism 19 (5), 883-890, 2014
512014
Functional characterization of native, high-affinity GABAA receptors in human pancreatic β cells
SV Korol, Z Jin, Y Jin, AK Bhandage, A Tengholm, NR Gandasi, S Barg, ...
EBioMedicine 30, 273-282, 2018
392018
Survey of red fluorescence proteins as markers for secretory granule exocytosis
NR Gandasi, K Vestö, M Helou, P Yin, J Saras, S Barg
PLoS One 10 (6), e0127801, 2015
382015
Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes
M Omar-Hmeadi, PE Lund, NR Gandasi, A Tengholm, S Barg
Nature communications 11 (1), 1-11, 2020
342020
Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis
A Guček, NR Gandasi, M Omar-Hmeadi, M Bakke, SO Døskeland, ...
Elife 8, e41711, 2019
332019
Recruitment of Epac2A to insulin granule docking sites regulates priming for exocytosis
I Alenkvist, NR Gandasi, S Barg, A Tengholm
Diabetes 66 (10), 2610-2622, 2017
292017
MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles
VA Salunkhe, JK Ofori, NR Gandasi, SA Salö, S Hansson, ME Andersson, ...
Physiological reports 5 (21), e13493, 2017
212017
The PI (4) P phosphatase Sac2 controls insulin granule docking and release
PM Nguyen, NR Gandasi, B Xie, S Sugahara, Y Xu, O Idevall-Hagren
Journal of Cell Biology 218 (11), 3714-3729, 2019
132019
Nanoscale Amperometry Reveals that Only a Fraction of Vesicular Serotonin Content is Released During Exocytosis from Beta Cells
A Hatamie, L Ren, H Dou, NR Gandasi, P Rorsman, A Ewing
Angewandte Chemie 133 (14), 7671-7674, 2021
122021
Syntaxin clusters at secretory granules in a munc18-bound conformation
P Yin, NR Gandasi, S Arora, M Omar-Hmeadi, J Saras, S Barg
Molecular biology of the cell 29 (22), 2700-2708, 2018
122018
PtdIns(4,5)P2 is not required for secretory granule docking
M Omar‐Hmeadi, NR Gandasi, S Barg
Traffic 19 (6), 436-445, 2018
92018
Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine–Glutamate Cycle
NR Gandasi, V Arapi, ME Mickael, PA Belekar, L Granlund, L Kothegala, ...
International journal of molecular sciences 22 (3), 1167, 2021
72021
MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells
VA Salunkhe, J Ofori, NR Gandasi, SA Salö, A Wendt, S Barg, ...
Diabetologia 58 (Suppl. 1), 128-128, 2015
52015
Fusion pore regulation by Epac2/cAMP controls cargo release during insulin exocytosis
A Gucek, NR Gandasi, M Omar-Hmeadi, M Bakke, S Doskeland, ...
Biophysical Journal 116 (3), 314a, 2019
32019
Statistical frailty modeling for quantitative analysis of exocytotic events recorded by live cell imaging: rapid release of insulin-containing granules is impaired in human …
G Cortese, NR Gandasi, S Barg, MG Pedersen
Plos one 11 (12), e0167282, 2016
32016
Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis
A Gucek, NR Gandasi, M Omar-Hmeadi, M Bakke, SO Doskeland, ...
Elife 8, 2019
22019
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Artiklar 1–20