| The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ... Nature medicine 23 (5), 631-637, 2017 | 368 | 2017 |
| 12, 13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake KI Stanford, MD Lynes, H Takahashi, LA Baer, PJ Arts, FJ May, AC Lehnig, ... Cell metabolism 27 (5), 1111-1120. e3, 2018 | 290 | 2018 |
| Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes R Xue, MD Lynes, JM Dreyfuss, F Shamsi, TJ Schulz, H Zhang, TL Huang, ... Nature medicine 21 (7), 760-768, 2015 | 265 | 2015 |
| Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts H Gardner, JR Shearstone, R Bandaru, T Crowell, M Lynes, ... Arthritis & Rheumatism 54 (6), 1961-1973, 2006 | 197 | 2006 |
| Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ... Nature medicine 24 (3), 292-303, 2018 | 165 | 2018 |
| TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism H Takahashi, CRR Alves, KI Stanford, RJW Middelbeek, P Nigro, ... Nature metabolism 1 (2), 291-303, 2019 | 161 | 2019 |
| 12-Lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat LO Leiria, CH Wang, MD Lynes, K Yang, F Shamsi, M Sato, S Sugimoto, ... Cell metabolism 30 (4), 768-783. e7, 2019 | 154 | 2019 |
| Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis EG Sustarsic, T Ma, MD Lynes, M Larsen, I Karavaeva, JF Havelund, ... Cell metabolism 28 (1), 159-174. e11, 2018 | 135 | 2018 |
| Deciphering adipose tissue heterogeneity MD Lynes, YH Tseng Annals of the New York Academy of Sciences 1411 (1), 5-20, 2018 | 100 | 2018 |
| CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice CH Wang, M Lundh, A Fu, R Kriszt, TL Huang, MD Lynes, LO Leiria, ... Science translational medicine 12 (558), eaaz8664, 2020 | 99 | 2020 |
| Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1-and CD36-mediated fatty acid uptake KL Townsend, D An, MD Lynes, TL Huang, H Zhang, LJ Goodyear, ... Antioxidants & redox signaling 19 (3), 243-257, 2013 | 97 | 2013 |
| Connexin 43 mediates white adipose tissue beiging by facilitating the propagation of sympathetic neuronal signals Y Zhu, Y Gao, C Tao, M Shao, S Zhao, W Huang, T Yao, JA Johnson, ... Cell metabolism 24 (3), 420-433, 2016 | 94 | 2016 |
| Interactions between CD36 and global intestinal alkaline phosphatase in mouse small intestine and effects of high-fat diet M Lynes, S Narisawa, JL Millán, EP Widmaier American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011 | 86 | 2011 |
| FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis F Shamsi, R Xue, TL Huang, M Lundh, Y Liu, LO Leiria, MD Lynes, ... Nature communications 11 (1), 1421, 2020 | 76 | 2020 |
| Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle A Castiglioni, S Hettmer, MD Lynes, TN Rao, D Tchessalova, I Sinha, ... Stem cell reports 2 (1), 92-106, 2014 | 76 | 2014 |
| Cold-activated lipid dynamics in adipose tissue highlights a role for cardiolipin in thermogenic metabolism MD Lynes, F Shamsi, EG Sustarsic, LO Leiria, CH Wang, SC Su, ... Cell reports 24 (3), 781-790, 2018 | 75 | 2018 |
| Defining the lineage of thermogenic perivascular adipose tissue AR Angueira, AP Sakers, CD Holman, L Cheng, MN Arbocco, F Shamsi, ... Nature metabolism 3 (4), 469-484, 2021 | 70 | 2021 |
| Vascular smooth muscle-derived Trpv1+ progenitors are a source of cold-induced thermogenic adipocytes F Shamsi, M Piper, LL Ho, TL Huang, A Gupta, A Streets, MD Lynes, ... Nature metabolism 3 (4), 485-495, 2021 | 69 | 2021 |
| Involvement of CD36 and intestinal alkaline phosphatases in fatty acid transport in enterocytes, and the response to a high-fat diet MD Lynes, EP Widmaier Life sciences 88 (9-10), 384-391, 2011 | 57 | 2011 |
| Endogenous fatty acid synthesis drives brown adipose tissue involution C Schlein, AW Fischer, F Sass, A Worthmann, K Tödter, MY Jaeckstein, ... Cell reports 34 (2), 2021 | 42 | 2021 |
Yu-Hua TsengJoslin Diabetes Center, Harvard Medical SchoolVerified email at joslin.harvard.edu
