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Kyle LaBella
Kyle LaBella
Verifierad e-postadress på gene.com
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Telomeres: history, health, and hallmarks of aging
D Chakravarti, KA LaBella, RA DePinho
Cell 184 (2), 306-322, 2021
3012021
Estrogen activation of G-protein–coupled estrogen receptor 1 regulates phosphoinositide 3-kinase and mTOR signaling to promote liver growth in zebrafish and proliferation of …
S Chaturantabut, A Shwartz, KJ Evason, AG Cox, K Labella, AG Schepers, ...
Gastroenterology 156 (6), 1788-1804. e13, 2019
872019
Telomere dysfunction activates YAP1 to drive tissue inflammation
D Chakravarti, B Hu, X Mao, A Rashid, J Li, J Li, W Liao, EM Whitley, ...
Nature communications 11 (1), 4766, 2020
582020
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood
O Weeks, GD Bossé, IM Oderberg, S Akle, Y Houvras, PJ Wrighton, ...
The Journal of clinical investigation 130 (5), 2252-2269, 2020
432020
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy
PJ Wrighton, A Shwartz, JM Heo, ED Quenzer, KA LaBella, JW Harper, ...
Journal of cell science 134 (4), jcs256255, 2021
362021
Histone demethylase KDM5D upregulation drives sex differences in colon cancer
J Li, Z Lan, W Liao, JW Horner, X Xu, J Liu, Y Yoshihama, S Jiang, ...
Nature 619 (7970), 632-639, 2023
272023
Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer
R Lee, J Li, J Li, CJ Wu, S Jiang, WH Hsu, D Chakravarti, P Chen, ...
Cancer discovery 12 (7), 1702-1717, 2022
222022
Oncogenic KRAS drives lipofibrogenesis to promote angiogenesis and colon cancer progression
WH Hsu, KA LaBella, Y Lin, P Xu, R Lee, CE Hsieh, L Yang, A Zhou, ...
Cancer discovery 13 (12), 2652-2673, 2023
112023
Estrogen acts through estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development
S Chaturantabut, A Shwartz, MK Garnaas, K LaBella, CC Li, KJ Carroll, ...
Hepatology 72 (5), 1786-1799, 2020
92020
AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase
Y Yoshihama, KA LaBella, E Kim, L Bertolet, M Colic, J Li, X Shang, ...
Proceedings of the National Academy of Sciences 118 (36), e2026324118, 2021
72021
Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer
J Han, J Xu, Y Liu, S Liang, KA LaBella, D Chakravarti, DJ Spring, Y Xia, ...
Genes & Development 37 (17-18), 818-828, 2023
12023
Quantitative intravital imaging reveals in vivo dynamics of physiological-stress induced mitophagy
PJ Wrighton, A Shwartz, J Heo, ED Quenzer, KA LaBella, J Wade
12020
Live imaging defines the dynamics and molecular basis of in vivo mitophagy
PJ Wrighton, A Shwartz, JM Heo, ED Quenzer, KA LaBella, JW Harper, ...
bioRxiv, 2020.03. 26.010405, 2020
12020
Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
KA LaBella, WH Hsu, J Li, Y Qi, Y Liu, J Liu, CC Wu, Y Liu, Z Song, Y Lin, ...
Developmental Cell, 2024
2024
Abstract IA20: Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer
J Han, J Xu, Y Liu, S Liang, KA LaBella, D Chakravarti, DJ Spring, Y Xia, ...
Cancer Research 84 (2_Supplement), IA20-IA20, 2024
2024
PRMT5 inhibition synergizes with a natural small molecule compound to kill MTAP-deleted cells and suppress tumor growth
Y Barekatain, K LaBella, H Sugimoto, K Harris, S Khadka, F Muller, ...
Cancer Research 83 (7_Supplement), 1073-1073, 2023
2023
Histone demethylase KDM5D drives sex-specific differences in colorectal cancer
J Li, Z Lan, W Liao, J Liu, S Jiang, HS Shim, M Slotnik, KA LaBella, ...
Cancer Research 83 (7_Supplement), 3515-3515, 2023
2023
Telomeric Regulation of Chromosomal Instability in Colorectal Cancer
KA LaBella
2023
Synthetic essentiality identifies TDO2 as a key target in APC-deficient CRC
R Lee, J Li, J Li, CJ Wu, S Jiang, WH Hsu, D Chakravarti, P Chen, ...
CANCER RESEARCH 82 (23), 5-6, 2022
2022
Abstract IA014: Synthetic essentiality identifies TDO2 as a key target in APC-deficient CRC
R Lee, J Li, J Li, CJ Wu, S Jiang, WH Hsu, D Chakravarti, P Chen, ...
Cancer Research 82 (23_Supplement_1), IA014-IA014, 2022
2022
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Artiklar 1–20