Följ
Virginia del Solar Fernández
Virginia del Solar Fernández
Senior Scientist at AstraZeneca
Verifierad e-postadress på astrazeneca.com
Titel
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Differential Regulation of Specific Sphingolipids in Colon Cancer Cells during Staurosporine-Induced Apoptosis
V del Solar, DY Lizardo, N Li, JJ Hurst, CJ Brais, GE Atilla-Gokcumen
Chemistry and Biology 22 (12), 1662-1670, 2015
602015
Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media
J Aleman, V del Solar, C Navarro-Ranninger
Chemical communications 46 (3), 454-456, 2010
432010
Metal-based antibody drug conjugates. Potential and challenges in their application as targeted therapies in cancer
V del Solar, M Contel
Journal of Inoranic Biochemistry 199, 2019
402019
Regioselective Ring Opening of Amino Epoxides with Nitriles:  An Easy Synthesis of (2R,3S)- and (2S,3S)-1,3-Diaminoalkan-2-ols with Differently Protected …
JM Concellón, JR Suárez, V Del Solar
The Journal of Organic Chemistry 70 (18), 7447-7450, 2005
332005
Evaluation of novel trans-sulfonamide platinum complexes against tumor cell lines
C Perez, CV Díaz-García, A Agudo-Lopez, V del Solar, S Cabrera, ...
European Journal of Medicinal Chemistry 76, 360-368, 2014
302014
Thioglycosides are efficient metabolic decoys of glycosylation that reduce selectin dependent leukocyte adhesion
SS Wang, X Gao, V Del Solar, X Yu, A Antonopoulos, AE Friedman, ...
Cell chemical biology 25 (12), 1519-1532. e5, 2018
292018
Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation
J Alemán, V del Solar, A Alvarez-Valdés, C Ríos-Luci, JM Padrón, ...
MedChemComm 2 (8), 789-793, 2011
272011
New reactions of anticancer-platinum complexes and their intriguing behaviour under various experimental conditions
J Alemán, V del Solar, L Cubo, AG Quiroga, CN Ranninger
Dalton Transactions 39 (44), 10601-10607, 2010
272010
Tandem Cyclization–Michael Reaction by Combination of Metal-and Organocatalysis
J Aleman, V del Solar, C Martín-Santos, L Cubo, CN Ranninger
The Journal of Organic Chemistry 76 (17), 7287-7293, 2011
242011
Expanding the synthesis of new trans-sulfonamide platinum complexes: cytotoxicity, SAR, fluorescent cell assays and stability studies
V Del Solar, A Quinones-Lombrana, S Cabrera, JM Padron, C Rios-Luci, ...
Journal of Inorganic Biochemistry 127, 128-140, 2013
232013
Total Selective Synthesis of Enantiopure O1-Acyl-3-aminoalkane-1,2-diols by Ring Opening of Aminoepoxides with Carboxylic Acids
JM Concellón, JR Suárez, V del Solar, R Llavona
The Journal of Organic Chemistry 70 (25), 10348-10353, 2005
212005
Synthesis of enantiopure allylamines by reductive alkylation of amino epoxides with organolithium reagents
JM Concellón, JR Suárez, V Del Solar
Organic Letters 8 (2), 349-351, 2006
192006
Robustness in glycosylation systems: Effect of modified monosaccharides, acceptor decoys and azido sugars on cellular nucleotide-sugar levels and the pattern of N-linked …
V del Solar, R Gupta, Y Zhou, G Pawlowski, KL Matta, S Neelamegham
Molecular omics, 2020
172020
Synthesis of Enantiopure (α S, β S)-or (α R, β S)-β-Amino Alcohols by Complete Regioselective Opening of Aminoepoxides by Organolithium Reagents LiAlH4 or LiAlD4
JM Concellón, PL Bernad, V del Solar, JR Suárez, S García-Granda, ...
The Journal of Organic Chemistry 71 (17), 6420-6426, 2006
172006
Encapsulation of Gold-Based Anticancer Agents in Protease-Degradable Peptide Nanofilaments Enhances Their Potency
Y Marciano, V Del Solar, N Nayeem, D Dave, J Son, M Contel, RV Ulijn
Journal of the American Chemical Society 145 (1), 234-246, 2022
152022
Intracellular localization studies of the luminescent analogue of an anticancer ruthenium iminophosphorane with high efficacy in a triple-negative breast cancer mouse model
K Miachin, V Del Solar, E El Khoury, N Nayeem, A Khrystenko, P Appelt, ...
Inorganic chemistry 60 (24), 19152-19164, 2021
142021
Unusual Totally Selective Cyclodimerization of Epoxides: Synthesis of a Pair of Diastereoisomers of Enantiopure 2,5‐Disubstituted‐1,4‐Dioxanes with C2 Symmetry
JM Concellon, PL Bernad, V del Solar, S García‐Granda, MR Diaz
Advanced Synthesis & Catalysis 350 (3), 477-481, 2008
142008
Ring opening of chiral 2-(1-aminoalkyl) epoxides by aliphatic thiols with total selectivity: synthesis of enantiopure 3-amino-1-(alkylthio) alkan-2-ols
JM Concellón, V del Solar, JR Suárez, EG Blanco
Tetrahedron 63 (13), 2805-2810, 2007
142007
Mass spectrometry-based metabolomics of value-added biochemicals from Ettlia oleoabundans
EK Matich, DM Butryn, M Ghafari, V del Solar, E Camgoz, BA Pfeifer, ...
Algal research 19, 146-154, 2016
132016
Efficient and Highly Selective Synthesis of Enantiopure cis- or trans-3,4-Disubstituted 1,2,3,4-Tetrahydroisoquinolines
JM Concellon, P Tuya, V del Solar, S Garcia-Granda, MR Díaz
Organic Letters 11 (16), 3750-3753, 2009
132009
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Artiklar 1–20