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Goodwell Nzou, PhD
Goodwell Nzou, PhD
Verifierad e-postadress på pennmedicine.upenn.edu
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Human cortex spheroid with a functional blood brain barrier for high-throughput neurotoxicity screening and disease modeling
G Nzou, RT Wicks, EE Wicks, SA Seale, CH Sane, A Chen, SV Murphy, ...
Scientific reports 8 (1), 1-10, 2018
1672018
Drug compound screening in single and integrated multi-organoid body-on-a-chip systems
A Skardal, J Aleman, S Forsythe, S Rajan, S Murphy, M Devarasetty, ...
Biofabrication 12 (2), 025017, 2020
1582020
Probing prodrug metabolism and reciprocal toxicity with an integrated and humanized multi-tissue organ-on-a-chip platform
SAP Rajan, J Aleman, MM Wan, NP Zarandi, G Nzou, S Murphy, ...
Acta biomaterialia 106, 124-135, 2020
1112020
Ultrasmall gold nanoparticles (2 nm) can penetrate and enter cell nuclei in an in vitro 3D brain spheroid model
V Sokolova, G Nzou, SB van der Meer, T Ruks, M Heggen, K Loza, ...
Acta biomaterialia 111, 349-362, 2020
602020
Multicellular 3D neurovascular unit model for assessing hypoxia and neuroinflammation induced blood-brain barrier dysfunction
G Nzou, RT Wicks, NR VanOstrand, GA Mekky, SA Seale, A El-Taibany, ...
Scientific reports 10 (1), 9766, 2020
582020
Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative …
K Oukoloff, G Nzou, C Varricchio, B Lucero, T Alle, J Kovalevich, L Monti, ...
Journal of medicinal chemistry 64 (2), 1073-1102, 2021
222021
In Zimbabwe, we don't cry for lions.
G Nzou
International New York Times, NA-NA, 2015
182015
Correction of microtubule defects within Aβ plaque‐associated dystrophic axons results in lowered Aβ release and plaque deposition
Y Yao, G Nzou, T Alle, W Tsering, S Maimaiti, JQ Trojanowski, VMY Lee, ...
Alzheimer's & Dementia 16 (10), 1345-1357, 2020
132020
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and …
T Alle, C Varricchio, Y Yao, B Lucero, G Nzou, S Demuro, M Muench, ...
Journal of Medicinal Chemistry 66 (1), 435-459, 2022
82022
Fundamental neurovascular components for the development of complex and dynamic in vitro brain equivalent models
G Nzou, MC Seeds, RT Wicks, AJ Atala
J. Alzheimers Neurodegener. Dis 5, 21, 2019
62019
Multicellular 3D neurovascular unit model for assessing hypoxia and neuroinflammation induced blood-brain barrier dysfunction. Sci Rep 10 (1): 9766
G Nzou, RT Wicks, NR VanOstrand, GA Mekky, SA Seale, A El-Taibany, ...
52020
Author Correction: Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction
G Nzou, RT Wicks, NR VanOstrand, GA Mekky, SA Seale, ELT Aya, ...
Scientific Reports 10, 2020
22020
Blood brain barrier model and methods of making and using the same
RT Wicks, A Atala, G Nzou, EE Wicks
US Patent App. 17/643,441, 2022
2022
Alzheimer’s in Screening Academia: to Disease In From Vivo High-Throughput Testing
KR Brunden, G Nzou, C Ballatore
Alzheimer's Disease Drug Development: Research and Development Ecosystem, 34, 2022
2022
Blood brain barrier model and methods of making and using the same
RT Wicks, A Atala, G Nzou, EE Wicks
US Patent 11,230,702, 2022
2022
3D Neurovascular Spheroid for Assessing Hypoxia Induced Blood-Brain Barrier Dysfunction
RT Wicks, G Nzou, N VanOstrand, G Mekky, S Seale, E Wicks, ...
Neurosurgery 67 (Supplement_1), 2020
2020
The Development of a Multicellular Three-Dimensional Neurovascular Unit Model for Studying Blood-Brain Barrier Integrity in Disease Pathologies
G Nzou
Wake Forest University, 2019
2019
The Development of a Human Cortex Model for High Throughput Neurotoxicity and Drug Screening
G Nzou, SS Seale, EE Wicks, RR Wicks, JD Jackson, AJ Atala
TISSUE ENGINEERING PART A 23, S106-S106, 2017
2017
Adhesive Film Based Multi-organoid Body-on-a-chip Platform For Assessing Drug Efficiency And Toxicity
S Rajan, J Aleman, M Wan, NP Zarandi, U Gandhi, G Nzou, CE Bishop, ...
TISSUE ENGINEERING PART A 23, S116-S116, 2017
2017
Bioprinted Blood Brain Barrier Model for Drug Screening
CH Sane, G Nzou, AJ Atala
TISSUE ENGINEERING PART A 23, S158-S158, 2017
2017
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Artiklar 1–20